A5054221861- Cancer Risks and Factors
- Nutritional Studies and Diet
- Cancer survivorship and care
- Obesity, Physical Activity, Diet
- Nutrition and Health in Aging
- Agriculture Sustainability and Environmental Impact
- Child Nutrition and Water Access
- Childhood Cancer Survivors' Quality of Life
- Metabolism, Diabetes, and Cancer
- Cancer-related cognitive impairment studies
- Adipokines, Inflammation, and Metabolic Diseases
- Regulation of Appetite and Obesity
- Food Security and Health in Diverse Populations
- Education and Critical Thinking Development
- Cardiovascular Disease and Adiposity
- Respiratory Support and Mechanisms
- Cancer Diagnosis and Treatment
- Diet and metabolism studies
- Obesity and Health Practices
- Sodium Intake and Health
- Hydraulic flow and structures
- Breast Cancer Treatment Studies
- Hydrology and Sediment Transport Processes
- Dietary Effects on Health
- Soil erosion and sediment transport
Yale University
2021-2024
Tufts University
2020
Nutrition Sciences (Belgium)
2020
Connecticut College
2016
Thomas Jefferson University
2014
Successful completion of chemotherapy is critical to improve breast cancer outcomes. Relative dose intensity (RDI), defined as the ratio delivered prescribed, a measure and associated with mortality. The effect exercise eating healthy diet on RDI unknown. We conducted randomized trial an nutrition intervention pathologic complete response (pCR) in women diagnosed initiating chemotherapy.
Abstract Background Little is known about improving physical activity (PA) and diet during after chemotherapy for breast cancer. This secondary analysis examines changes in PA quality a yearlong intervention patients with cancer undergoing evaluates factors associated these changes. Methods Newly diagnosed ( N = 173) were randomized to year‐long nutrition exercise n 87) or usual care (UC, 86). Mixed models compared 1‐year via the Healthy Eating Index (HEI)‐2015 by study arm. Among group,...
Background: Lifestyle interventions for breast cancer survivors have proved effective at stimulating positive behavior change and promoting healthy weight loss, although integrating these programs into clinical practice is challenging. We evaluated the effect of a 6-month, unsupervised, self-guided, lifestyle intervention using printed materials online videos vs. waitlist group on body survivors. Methods: The Lifestyle, Exercise Nutrition (LEAN) Self-Guided trial randomized with mass index...
Abstract Weight gain after breast cancer diagnosis is associated with adverse health outcomes. Yet, few studies have characterized post-diagnosis weight change in the modern treatment era or populations most at risk for changes. Among women diagnosed stages I–III Smilow Care Network (2013–2019; N = 5441), we abstracted demographic and clinical characteristics from electronic records survival data tumor registries. We assessed if baseline modified trajectories nonlinear multilevel...
Objective Adiponectin (APN) is an anti-inflammatory hormone derived from adipose tissue that attenuates acute lung injury in rodents. In this study, we investigated the association between circulating APN and outcomes among patients with respiratory distress syndrome (ARDS). Methods We performed a retrospective cohort study using data plasma samples participants multicenter ARDS Network Fluid Catheter Treatment Trial. Results Plasma concentrations were measured 816 (81.6%) trial at baseline...
Abstract Obesity among breast cancer survivors is associated with increased risk for recurrence and mortality. The hormone ghrelin plays a role in initiating appetite thus regulating body weight. This study aims to determine the effect of lifestyle intervention on levels mass index (BMI) ≥ 25 kg/m 2 . Lifestyle, Exercise, Nutrition (LEAN) was 6-month randomized trial, examining effectiveness weight loss versus usual care 151 BMI Ghrelin measured fasting baseline blood samples. Baseline...
The relationship between animal source foods (ASF) and growth outcomes is not well characterized, largely due to few studies inconsistencies across study designs. We investigated the associations mean ASF intake, under-5 mortality disability-adjusted life years (DALYs) linked stunting, wasting, underweight overweight/obesity in children aged 6–59 months. Intakes of (unprocessed red meat, processed fish, eggs, milk, yogurt cheese), adjusted 1000 kcal/day, were estimated using individual-level...
Global nutrition research and dietary recommendations have focused on infants/young children or adults with limited attention the crucial ages of adolescents. Diet quality during adolescence is critical to support physical mental development promote healthy behaviors in adulthood. Our objective was estimate consumption plant source foods (PSF) animal (ASF) among adolescents age 11–19 years globally. The Dietary Database 2015 (GDD) includes national subnational individual-level intake survey...
Abstract Background: The association between obesity and breast cancer risk is well documented, but fewer studies have explored the impact of post diagnosis weight changes on survival especially in more contemporary contexts. existing evidence has mainly focused gain, been limited by small sample sizes evaluated prospective cohorts with restrictive eligibility criteria rather than population-based samples. Our study uniquely contributes to literature using a approach recent clinically...
Abstract Background: Neoadjuvant chemotherapy is available to women with locally advanced breast cancer where given prior surgery. By examining resected tissue following neoadjuvant pathological complete response (pCR) can be determined. pCR a favorable prognostic factor associated longer survival compared residual disease after chemotherapy. Physical activity and diet may improve some side effects during treatment, but less known about their effect on completion more specifically in the...
To prioritize dietary factors for reducing the growing burden of type 2 diabetes (T2D) worldwide, we estimated impact suboptimal diet on T2D incidence at global, regional, national, and subnational levels between 1990 2015. A comparative risk assessment framework attributable to in strata jointly stratified by year, nation, age, sex, across 185 countries. We direct (dietary composition) etiologic effects 8 including nuts/seeds, whole grains, yogurt, processed meats, unprocessed red glycemic...
Empirical evidence on the relationship between diet quality metrics and child growth outcomes is sparse. We investigated associations Infant Young Child Minimum Dietary Diversity (IYCMDD) Approaches to Stop Hypertension (DASH) scores, under-5 mortality disability-adjusted life years (DALYs) due stunting, wasting, underweight overweight/obesity in children aged 6–59 months. The Global Database (GDD) uses Bayesian hierarchical modeling methods combine individual-level dietary intake from...
In 2019, the EAT-Lancet Commission proposed global dietary targets for healthy diets and sustainable food production. Actual intakes worldwide, based on individual-level data, in relation to these are uncertain. The Global Dietary Database 2015 (GDD) collected analyzed intake data 55 factors from 1144 nationally- or sub-nationally-representative surveys. A Bayesian hierarchical model combined stratum-specific, with survey-specific characteristics time-varying country-level covariates (GDP,...
Given the major interest in plant-based foods (PF) for global diets, we aimed to characterize inequalities intakes of fruits, vegetables (non-starchy, potatoes, other starchy), legumes, grains (refined, whole), and nuts/seeds by country wealth population socioeconomic status (SES). PF were derived from Global Dietary Database, including 1144 national subnational surveys 1980 through 2015 covering 97.5% world's population. A Bayesian hierarchical prediction model combined stratum-specific...
Assessing the impact of beverage intake on health has been limited by lack reliable and standardized individual-level data a global scale. We provide updated estimates intakes sugar-sweetened beverages (SSBs), fruit juices, milk, as well novel coffee tea, jointly country, age, sex, education, urban-rural residence for adults in 2015. Beverge Global Dietary Database were derived from 1144 national subnational surveys 1980 through 2015, covering 97.5% world's population. Mean 95% uncertainty...
12007 Background: In observational studies, 25%-55% of women with breast cancer (BC) do not complete chemotherapy as initially prescribed, primarily due to toxicity. Relative dose intensity (RDI) is an integrated measure delays and reductions associated mortality. Physical activity (PA) diet may reduce treatment toxicity, but less known about their effect on RDI. We conducted a randomized trial PA intervention RDI (primary endpoint) in newly diagnosed BC initiating chemotherapy. Methods: 173...
Background: Delivering difficult news to patients and families is an essential but challenging communication skill. Currently, little information exists regarding the role that non-physician team members play during disclosure of pediatric patients. Specific Aim: We conducted qualitative interviews examine roles healthcare process delivery families, including before, during, after disclosure. Methods: Design: implemented a research study based in grounded theory. Sample: interviewed members,...