A5026441079- Radiation Therapy and Dosimetry
- Advanced Radiotherapy Techniques
- Nuclear Physics and Applications
- Radiation Detection and Scintillator Technologies
- Radiation Dose and Imaging
- Medical Imaging Techniques and Applications
- Graphite, nuclear technology, radiation studies
- Nuclear reactor physics and engineering
- Advanced X-ray and CT Imaging
- Atomic and Subatomic Physics Research
- Lymphoma Diagnosis and Treatment
- Lung Cancer Diagnosis and Treatment
- Radiation Effects and Dosimetry
- Particle accelerators and beam dynamics
- Radiation Effects in Electronics
- Systemic Sclerosis and Related Diseases
- Breast Cancer Treatment Studies
- Effects of Radiation Exposure
- Cardiovascular and Diving-Related Complications
- Digital Radiography and Breast Imaging
- Supramolecular Self-Assembly in Materials
- Prostate Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Photochromic and Fluorescence Chemistry
- Polydiacetylene-based materials and applications
Hospital Del Mar
2025
Hospital del Mar Research Institute
2025
Karolinska Institutet
2022-2024
Universidad de Sevilla
2011-2023
Instituto de Investigaciones Químicas
2023
Universitat Autònoma de Barcelona
2014-2022
Instituto Tecnológico de Santo Domingo
2020-2021
P. D. Hinduja Hospital and Medical Research Centre
2016
National Hospital
2016
Kyoto University
2016
To characterize stray radiation around the target volume in scanning proton therapy and study performance of active neutron monitors.Working Group 9 European Radiation Dosimetry (EURADOS WG9-Radiation protection medicine) carried out a large measurement campaign at Trento Centro di Protonterapia (Trento, Italy) order to determine spectra near patient using two extended-range Bonner sphere spectrometry (BSS) systems. In addition, work focused on acknowledging different commercial dosimetry...
Neutron peripheral contamination in patients undergoing high-energy photon radiotherapy is considered as a risk factor for secondary cancer induction. Organ-specific neutron-equivalent dose estimation therefore essential reasonable assessment of these associated risks. This work aimed to develop method estimate doses multiple organs patients. The involved the convolution, at 16 reference points an anthropomorphic phantom, normalized Monte Carlo neutron fluence energy spectra with kerma and...
Abstract Objective This study aims to compare the accuracy of digital mammography (DM), breast tomosynthesis (DBT), ultrasound (US), magnetic resonance imaging (MRI), and contrast-enhanced (CEM) in preoperative evaluation cancer size architectural distortions (ADs). Additionally, it assesses whether including thin spicules measurements affects accuracy. Materials methods We planned a retrospective analysis invasive cancers presenting as ADs our screening program between 2018 2022. Tumor was...
The purpose of this study is to characterize the stray neutron radiation field in scanning proton therapy considering a pediatric anthropomorphic phantom and clinically-relevant beam condition.
Systematic 3D mapping of out-of-field doses induced by a therapeutic proton pencil scanning beam in 300 × 600 mm3 water phantom was performed using set thermoluminescence detectors (TLDs): MTS-7 (7LiF:Mg,Ti), MTS-6 (6LiF:Mg,Ti), MTS-N (natLiF:Mg,Ti) and TLD-700 radiophotoluminescent (RPL) GD-352M GD-302M, polyallyldiglycol carbonate (PADC)-based (C12H18O7) track-etched detectors. Neutron gamma-ray doses, as well linear energy transfer distributions, were experimentally determined at 200...
The objective of this work is to evaluate the risk carcinogenesis low dose ionizing radiation therapy (LDRT), for treatment immune-related pneumonia following COVID-19 infection, through estimation effective and lifetime attributable cancer (LAR).LDRT was planned in male female computational phantoms. Equivalent doses organs were estimated using both planning system calculations a peripheral model (based on ionization chamber measurements). Skin radiochromic films. Later, LAR calculated...
This work aims to generate a simple analytical model that allows estimation of peripheral photon equivalent dose organs individual patients, valid for any isocentric technique. Photon radiation scattered in the LINAC head has been simulated as virtual source emitting isotropically so that, before reaching point inside patient, it decreases with square law and attenuation due air tissue. Leakage constant background along patient. Firstly, dose-to-points basic was proposed parameterized by...
Purpose: The evaluation of peripheral dose has become a relevant issue recently, in particular, the contribution secondary neutrons. However, after revision Recommendations International Commission on Radiological Protection, there been lack experimental procedure for its evaluation. Specifically, problem comes from replacement organ equivalent by organ-equivalent dose, being latter "immeasurable" definition. Therefore, to be still used although it needs calculation radiation quality factor...
This study aims to characterize the neutron radiation field inside a scanning proton therapy treatment room including impact of different pediatric patient sizes. Working Group 9 European Radiation Dosimetry (EURADOS) has performed comprehensive measurement campaign measure ambient dose equivalent, H*(10), at eight positions around 1-, 5-, and 10-year-old anthropomorphic phantoms irradiated with simulated brain tumor treatment. Several active detector systems were used. The mapping within...
Since 2010, EURADOS Working Group 9 (Radiation Dosimetry in Radiotherapy) has been involved the investigation of secondary and scattered radiation doses X-ray proton therapy, especially case pediatric patients. The main goal this paper is to analyze compare out-of-field neutron non-neutron organ inside 5- 10-year-old anthropomorphic phantoms for treatment a 5-cm-diameter brain tumor. Proton irradiations were carried out at Cyclotron Centre Bronowice IFJ PAN Krakow Poland using pencil beam...
Proton beam therapy has advantages in comparison to conventional photon radiotherapy due the physical properties of proton beams (e.g. sharp distal fall off, adjustable range and modulation). In therapy, there is possibility sparing healthy tissue close target volume. This especially important when tumours are located next critical organs while treating cancer paediatric patients. On other hand, interactions protons with matter result production secondary radiation, mostly neutrons gamma...
Purpose: Peripheral dose in radiotherapy treatments represents a potential source of secondary neoplasic processes. As the last few years, there has been fast‐growing concern on neutron collateral effects, this work focuses component. A previous established methodology to estimate peripheral equivalent doses relied passive (TLD, CR39) detectors exposed in‐phantom, parallel an active [static random access memory ( SRAMnd )] thermal detector ex‐phantom. newly miniaturized, quick, and reliable...
The HOmogeneous Thermal NEutron Source (HOTNES) is a new type of thermal neutron irradiation assembly developed by the ENEA-INFN collaboration. facility fully characterized in terms field and dosimetric quantities, either computational experimental methods. This paper reports results first "HOTNES users program"", carried out 2016, covering variety active detectors such as scintillators, solid-state, single crystal diamond gaseous detectors.
Out-of-field patient doses in proton therapy are dominated by neutrons. Currently, they not taken into account treatment planning systems. There is an increasing need to include out-of-field the dose calculation, especially when treating children, pregnant patients, and patients with implants. In response this demand, work presents first steps towards a tool for prediction of neutron pencil beam scanning facilities. As step, general Monte Carlo radiation transport model simulation was set up...
Knowing the contribution of neutron to collateral effects in treatments is both a complex and mandatory task. This work aims present an operative procedure for estimates any facility using digital detector.The authors' previous established linear relationship between total second cancer risk due neutrons (TR(n)) number MU treatment. Given that detector also presents linearity with MU, its response can be used determine TR(n) per unit denoted as m, normally associated generic Linac model...
The aim of this work is to present a reproducible methodology for the evaluation total equivalent doses in organs during proton therapy facilities. based on measuring dose representative locations inside an anthropomorphic phantom where photon and neutron dosimeters were inserted. Monte Carlo simulation was needed obtaining energy distribution phantom. implemented head irradiation case passive beam iThemba Labs (South Africa). Thermoluminescent dosimeter (TLD)-600 TLD-700 pairs used as GEANT...
Divergent synthesis of stimuli-responsive biomaterials with varied sizes and topologies for potential applications in cancer theranostics, tissue engineering, catalysis.
Linear accelerators for medical purposes represent a source of photoneutron radiation at high energy photon therapy modalities. In this clinical scenario, measurement the neutron field is demanding task due to in-room fluence and its pulsed time structure. The interaction neutrons with SRAM memory cells can produce upsets in state. This effect has been exploited device composed type memories used as detector. mainly sensitive low neutrons, characterized previously different dedicated...