A5085429355- Graphene research and applications
- Bone Tissue Engineering Materials
- Graphene and Nanomaterials Applications
- Carbon Nanotubes in Composites
- Hydrogels: synthesis, properties, applications
- Supramolecular Self-Assembly in Materials
- Nanoplatforms for cancer theranostics
- Micro and Nano Robotics
- Supercapacitor Materials and Fabrication
- Nanoparticle-Based Drug Delivery
- 3D Printing in Biomedical Research
- Electrospun Nanofibers in Biomedical Applications
- Polymer Nanocomposite Synthesis and Irradiation
- Polymer Nanocomposites and Properties
- Electrochemical sensors and biosensors
- Conducting polymers and applications
- Polymer composites and self-healing
- Click Chemistry and Applications
- Advanced Materials and Mechanics
- Pickering emulsions and particle stabilization
- Glycosylation and Glycoproteins Research
- Block Copolymer Self-Assembly
- Proteoglycans and glycosaminoglycans research
- Carbon and Quantum Dots Applications
- Polydiacetylene-based materials and applications
Universidad de Granada
2018-2023
National Polytechnic School
2022
Pontifical Catholic University of Rio de Janeiro
2017-2020
Consejo Superior de Investigaciones Científicas
2010-2017
Instituto de Ciencia de Materiales de Madrid
2012-2017
Institute of Mechanical Engineering and Industrial Mangement
2013
Sapienza University of Rome
2009-2012
University of L'Aquila
2008
National Agency for New Technologies, Energy and Sustainable Economic Development
2007
A novel procedure for the in situ rapid chemical gelation of aqueous solutions hyaluronan has been employed. In brief, water-soluble polysaccharide derivatives bearing side chains endowed with either azide or alkyne terminal functionality have prepared. When latter two types are mixed together solution they give rise to a 1,3-dipolar cycloaddition reaction resulting fast (in presence catalytic amounts Cu(I)) at room temperature. Gel formation characterized rheologically and could also be...
Gelatin is one of the most commonly used biopolymer for creating cellular scaffolds due to its innocuous nature. To create stable gelatin at physiological temperature (37 degrees C), chemical cross-linking a necessary step. In previous paper (Biomacromolecules 2006, 7, 3059-3068), was carried out by either radical polymerization methacrylated derivative (GMA) or through formation isopeptide bonds catalyzed transglutaminase. The method scaffold production based on emulsion templating in which...
Abstract The treatment of bone lesions, including fractures, tumor resection and osteoporosis, is a common clinical practice where healing repair are pursued. It widely accepted that calcium phosphate‐based materials improve integration biomaterials with surrounding tissue further serve as template for proper function bone‐forming cells. Within this context, mineralization on preformed substrates appears an interesting successful alternative mineral surface functionalization. However, “true”...
The development of blended gelatin and glycosaminoglycan (GAG) scaffolds can potentially be used in many soft tissue engineering applications since these mimic the structure biological function native extracellular matrix (ECM). In this study, we were able to obtain a gelatin–GAG scaffold by using concentrated emulsion templating technique known as high internal phase (HIPE), which prevailing volume organic is dispersed form discrete droplets inside an aqueous solution three biopolymers...
Liquid marbles (LMs) are nonsticky droplets covered by micro- or nanometrically scaled particles and obtained simply rolling small amounts of a liquid in very hydrophobic powder. Since pioneer work Aussillous Quéré, wide palette materials for the preparation LMs, as well potential applications, have been reported. Because bioinspired origin this concept, applicability LMs biomedicine is gaining increasing attention, with remarkable advances their use microbioreactors blood typing, drug...
Recent advances in nanotechnology have permitted the development of a wide repertoire inorganic magnetic nanoparticles (NPs) with extensive promise for biomedical applications. Despite this remarkable potential, many questions still arise concerning biocompatible nature NPs when contact biological systems. Herein, we investigated how controlled changes physicochemical properties iron oxide at their surface (i.e., charge and hydrodynamic size) affect, first, interaction cell media components...
The immobilization of more than one single substance within the structure a biocompatible polymer provides multifunctional biomaterials with attractive and enhanced properties. In context bone tissue engineering, it could be great interest to synthesize biomaterial that simultaneously contains amorphous calcium phosphate (ACP), favor precipitation promote osteogenesis, an antibiotic such as ciprofloxacin (CFX) can, eventually, avoid infections resulting after surgical scaffold implantation....
Microbial diseases have been declared one of the main threats to humanity, which is why, in recent years, great interest has generated development nanocomposites with antimicrobial capacity. The present work studied two magnetic based on graphene oxide (GO) and multiwall carbon nanotubes (MWCNTs). synthesis these consisted three phases: first, iron nanoparticles (MNPs), second, adsorption photosensitizer menthol-Zinc phthalocyanine (ZnMintPc) into MWCNTs GO, third phase, encapsulation poly...
Numerous strategies that are currently used to regenerate bone depend on employing biocompatible materials exhibiting a scaffold structure. These scaffolds can be manufactured containing particular active compounds, such as hydroxyapatite precursors and/or different growth factors enhance regeneration process. Herein, we have immobilized calcium phosphate salts (CPS) and morphogenetic protein 2 (BMP-2) – combined or alone into chitosan using ISISA We analyzed whether the preserved its...
Deep eutectic solvents promoted the stabilization of collapsed state elastin-like recombinamers – and subsequent formation aggregates upon loss structural water molecules involved in hydrophobic hydration. Cryo-etch scanning electron microscopy allowed observation these neat deep solvents. The suppression lower critical solution temperature transition, observed by differential calorimetry dynamic light scattering, confirmed presence their state. Actually, transition from to expanded was...
Carbon nanotubes (CNTs) have lately attracted significant attention in the field of biomedicine. Although a wide repertoire CNT-based composites has been explored as substrates for cell growth, fabrication 3D scaffolds more rarely accomplished. Additionally, concerns referred to CNT biocompatibility make their use biomaterials still controversial. Herein we explore interaction three types - prepared with multi-walled CNTs and processed show different architectural morphological features at...
The use of polyethylene oxide-polypropylene oxide-polyethylene oxide block-copolymers as a mediator in the laccase-induced graft polymerization diacrylic derivate glycols resulted formation PEG-g-F68 hydrogels. proper oxygen content reaction medium to obtain reasonable conversions (i.e., on one hand, laccase needs substrate whereas, other, is strong inhibitor radical polymerizations) was achieved by an enzymatic scavenging system consisting glucose oxidase and glucose. Eventually,...
Microbial diseases have been declared one of the main threats to humanity, which is why, in recent years, great interest has generated development nanocomposites with antimicrobial capacity. In present work, two magnetic nanocomposites, based on Graphene Oxide (GO) and Multiwall Carbon Nanotubes (MWCNTs) were studied. The synthesis these consisted three phases: first, Iron Magnetic Nanoparticles (MNPs) was carried out presence MWCNTs GO using Co-precipitation method. second phase adsorption...
Divergent synthesis of stimuli-responsive biomaterials with varied sizes and topologies for potential applications in cancer theranostics, tissue engineering, catalysis.
RESUMO Neste trabalho foram preparadas dispersões aquosas de óxido grafeno (GO) e reduzido (rGO), em diferentes tempos oxidação, com o objetivo verificar a influência do tempo oxidação relação às características das folhas (flakes) finais. As GO pelo método Hummers modificado utilizando os seguintes oxidação: 4 h; 1 dia; 3 dias; 7 dias 10 dias. Em seguida, as submetidas ao tratamento redução ácido ascórbico, obtendo-se rGO. caracterizações amostras realizadas por meio análises espectroscopia...