Pre-implantation development arrest poses a significant challenge in infertility treatment cycles. This study aims to evaluate the effect of Insulin, Transferrin, Selenium (ITS), and CHIR99021 on arrested human embryos. Arrested embryos were obtained from Embryology Department Royan Institute. After determining optimal concentrations, assigned control, CHIR99021, ITS groups cultured for 48–72 h. The rate significantly decreased compared control group (P < 0.05). developmental up pre-morula...

Introduction Thyroid diseases are associated with skin-related chronic and autoimmune complications. Among these disorders, vitiligo is considered a problem affecting individuals' quality of life. In this study, we investigated the frequency among patients thyroid diseases. Methods This cross-sectional study was conducted on 724 dysfunction referred to Razi Clinic in Rasht, Iran, 2022. Dermatologists endocrinologists diagnosed diseases, respectively. Patients' demographic clinical data were...

Female sex workers (FSWs) in most societies run a high risk of health problems, including sexually transmitted infections (STIs) such as viral and syphilis. The present study examines the prevalence syphilis among FSWs.

One of the shortcomings available treatments for major depressive disorder (MDD) is time delay between starting treatment and achieving an antidepressant response.We aimed to determine effect Ketamine as a synergistic anesthetic agent on MDD in electroconvulsive therapy (ECT).Twenty-two patients with received Propofol agents compared 20 control group who double-blind randomized clinical trial. The Hamilton rating scale depression was used changes symptoms severity during ECT 2-week...

Permethrin, a pyrethroid insecticide, is not yet available in Iran and may be useful substitute for the control of scabies Iran.To compare efficacy topical lindane with permethrin treatment population Iran.In double-blind, randomized study, all consecutive patients were into two groups. One group their family contacts received 1% cream, other treated 5% cream. Subsequently, followed up at 2- 4-week post-treatment.Of 99 enrolled 47 52 topically Permethrin provided an improvement rate 84.6%...

Aim Effects of vitamin D supplementation on the glycaemic indices and insulin resistance in diabetic non-diabetic patients were studied. In this study, effects stress-induced hyperglycaemia evaluated surgical critically ill patients. Methods Adult with within first 24 h admission to ICU recruited. The randomly assigned receive either or placebo. Patients group received a single dose 600,000 IU D3 as intramuscular injection at time recruitment. Besides demographic clinical characteristics...

Background: Hirsutism can have negative impacts on psychosocial aspects of women's lives and reduce their quality life (QOL). The aim this study was to assess the QOL these women during laser treatment. Patients methods: Eighty-eight with unwanted facial hair underwent therapy. Each patient completed a questionnaire consisting modified Dermatology Life Quality Index (DLQI) visual analog scale (VAS) before first, third, fifth sessions Interval between 4–6 weeks. Statistical analyses were done...

Background. Topical agents can be unpleasant due to long-term therapies in patients with moderate severe seborrheic dermatitis. Systemic antifungal therapy is another alternative treatment. Aim. This study was conducted compare the efficacy of oral fluconazole and terbinafine treatment Methods. 64 dermatitis (SD) were enrolled a randomized, parallel-group study. One group took 250 mg daily (n = 32) other one 300 weekly for four weeks. Seborrheic area severity index (SDASI) intensity itching...

Pruritus is among the most common complaints in field of dermatology. It also a disturbing symptom many systemic disorders. Chronic pruritus (CP) refers to cases which last longer than 6 weeks. We conducted prospective analysis patients with generalized without primary skin lesions. All underwent evaluations and then were followed from 12 18 months for further evaluations. Of 5,127 referred our dermatology clinic, 49 lesions evaluated. Most (44%) age group 40–60 years female (58%). The...

Abstract Background Dermoscopy can be helpful in assessing nonpigmented lesions and inflammatory processes like lichen planopilaris (LPP). Material &amp; Methods In this observational prospective study, 81 patients with a cicatricial alopecic patch on their scalp were included underwent dermatologic examination. A biopsy was taken from the active part of lesion based dermoscopy evaluation. Results Analysis 44 definite diagnosis LPP revealed that mean age at time presentation 44.05 ± 12.62...

Dermoscopy has emerged as a useful diagnostic tool to evaluate skin lesions, including psoriasis. We aimed compare the clinical examination and digital dermoscopy findings of nail involvement in patients with psoriatic nails.

Isolated distant cutaneous metastasis of breast carcinoma is uncommon. Furthermore, isolated the scalp seems to be very rare in cancer.A 44-year-old woman was referred our dermatology department with concerns a firm, painless, immobile, hardened, skin-colored mass fixed underlying tissues. The lesion measured 2 3 cm on frontalis without regional or lymphadenopathy. patient had history benign right biopsy test results.Immunohistochemistry results were positive for cytokeratin (AE1/AE3), 7,...

Geriatric health care has become a worldwide concern, but few statistical studies were carried out about skin diseases in this age group the nursing home of Iran.In study, we set to determine frequency as well and gender distribution dermatological old residents.In cross-sectional all patients over 60 years who living charity complex Rasht 2017 participated study. Baseline information on sociodemographic variables, past medical history, medication gathered by staff during face-to-face...

Background Chronic telogen effluvium (CTE) is a form of diffuse hair loss in middle-aged women whom continues more than 6 months without obvious etiology. Disturbance growth cycle may result increased hairs the phase. Micronutrient deficiency, such as iron, zinc, and vitamin D, has been incriminated acute but its role chronic phases challenging. Objective To measure levels serum ferritin, 25-hydroxy D (25OH D) females with CTE controls to verify their hair-loss pathogenesis. Patients methods...

Background &amp; Objective: The present study was conducted to determine testosterone and ferritin levels in women with polycystic ovary syndrome (PCOS) investigate its relationship body mass index (BMI)&#x0D; Materials Methods: In this case-control study, 104 PCOS cases 99 controls were included. concentration of testosterone, ferritin, lipid profile, insulin, glucose, androgen measured fasting blood samples.&#x0D; Results: Testosterone level equal 1.08 ± 0.50 0.85 0.42 the case control...