- Medical Imaging and Pathology Studies
- Lung Cancer Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Transplantation: Methods and Outcomes
- Tracheal and airway disorders
- Neuroblastoma Research and Treatments
- Neurofibromatosis and Schwannoma Cases
- Congenital Diaphragmatic Hernia Studies
- Pleural and Pulmonary Diseases
- Lung Cancer Treatments and Mutations
- Cancer Diagnosis and Treatment
- Organ Transplantation Techniques and Outcomes
- Airway Management and Intubation Techniques
- Myasthenia Gravis and Thymoma
- Gastrointestinal Tumor Research and Treatment
- MicroRNA in disease regulation
- Mesenchymal stem cell research
- Cutaneous Melanoma Detection and Management
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Venous Thromboembolism Diagnosis and Management
- Vascular Malformations and Hemangiomas
- Angiogenesis and VEGF in Cancer
- Neurological and metabolic disorders
- Adenosine and Purinergic Signaling
- Influenza Virus Research Studies
Kōchi University
2023
Ohta Nishinouchi Hospital
2018-2020
Tohoku University Hospital
2013-2020
Cleveland Clinic
2020
Cleveland Clinic Lerner College of Medicine
2020
Tohoku University
1993-2019
St Thomas' Hospital
2018
Tohoku Medical and Pharmaceutical University Hospital
2012-2014
Iwate Prefectural Central Hospital
2014
Tohoku Medical and Pharmaceutical University
2013
Preparation of hydroxyapatite was carried out by a homogeneous precipitation technique using hydrothermal reactions Ca(EDTA)2- and PO4(3-) at 130-250 degrees C pH 4-10. Hydroxyapatite monetite were formed above 6 below 4, respectively. Needle-like high temperatures 130 C. The length the needle-like crystal increased with increasing working solution temperature.
Posttransplantation lung ischemia–reperfusion (IR) injuries affect both patient survival and graft function. In this study, we evaluated the protective effects of infused human multilineage-differentiating stress-enduring (Muse) cells, a novel, easily harvested type nontumorigenic endogenous reparative stem cell, against acute IR injury in rat model. After 2-h warm induction left lung, Muse mesenchymal cells (MSCs), vehicle were injected via pulmonary artery after reperfusion. Functionality,...
F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) has become an important staging tool for patients with lung cancer, and determination of the standardized uptake value (SUV) is probably most widely used method evaluating patients. Although SUV recognized as a powerful surrogate marker cancer outcomes, standardization reproducibility in clinical practice remain major concerns. The aim this study was to evaluate corrected universal recurrence.We conducted case-control our...
Abstract Background and Aim Vasohibin‐1 (VASH1) is an angiogenesis inhibitor synthesized secreted by endothelial cells, whose expression induced angiogenic stimuli such as vascular growth factor. We have previously demonstrated that VASH1 immunohistochemically evident in cells the tumor microenvironment of patients with non–small cell lung cancer (NSCLC) positively correlated factor cells. Here, we determined preoperative plasma concentration NSCLC evaluated association between levels...
A 74-year-old man presented with chest pain and high-grade fever. Chest radiography revealed a consolidation in the right lower lung lobe, computed tomography demonstrated atelectasis infiltration of pleural effusion. Bronchoscopy tumor occluding inlet lateral/posterior basal segmental bronchus lung, but bronchoscopic biopsy did not lead to definitive diagnosis. Considering possibility obstructive pneumonia pleuritis, we performed lobectomy, decortication, pleuroclysis. Pathological...
Abstract Background The therapeutic drug monitoring of mycophenolic acid (MPA) has been investigated for renal and heart transplantations; however, its usefulness in lung transplantation is unclear. Methods MPA area under the plasma concentration–time curve (AUC) was calculated 59 adult transplant recipients. AUC 0‐12 s were compared among three groups determined by presence adverse events (no events, infection, chronic allograft dysfunction [CLAD]). Next, thresholds identified receiver...
Thymic carcinomas are a rare type of malignant mediastinal tumor. have rapid progression, and recurrence metastasis usually occur in the early phase after surgical resection. To best our knowledge, more than 10 years resection has been reported only one case neuroendocrine cell carcinoma. We report resected thymic squamous carcinoma recurring years, which indicates that require long-term follow-up
症例は28歳,男性.2010年6月末に心窩部痛を訴え当科紹介になった.CTで上腹部に約5cmの腫瘤を認めたため,精査を行った.上部消化管内視鏡では十二指腸球部前壁に粘膜下腫瘍様の隆起を認めた.MRIではT1強調で低信号,T2強調で不均一な高信号を示す腫瘤で,内部は不均一に造影された.FDG(18F-fluoro-2-deoxy-D-glucose)-PET(positron emission tomography)では腫瘤に一致してmax SUV 7.4/10.6と集積の亢進を認めた.確定診断をつけるため施行したEUS(endoscopic ultrasound)-FNAB(guided fine-needle aspiration biopsy)では紡錘形の細胞の増殖および広範囲の壊死を認め,免疫染色でS-100が陽性であったことから悪性末梢神経鞘腫瘍が否定できなかった.手術は腫瘍摘出術を施行した.摘出標本での病理組織診断では壊死は虚血性と考えらえ,MIB-1...
症例は81歳,男性.2002年5月に上行結腸癌で右半結腸切除術を施行された.病理病期はStageIIIAであった.術後化学療法としてドキシフルリジン800mg/日を2年間内服していた.2007年3月CTにて右肺S4に内部に石灰化を伴う腫瘤を指摘された.2007年4月右中葉切除術を施行した.病理組織学的所見は大腸癌肺転移であり,一部に骨形成を認めた.原発巣に骨形成を認めず,肺転移巣にのみ骨形成を認めた.このような例は非常にまれであり,文献的考察を加えて報告する.