Abstract Background Accumulating data point to a potential role of prolactin in the pathogenesis psoriasis. Methods We initiated study including psoriasis patients ( n = 15) and healthy volunteers as controls. Psoriasis area severity index (PASI) score was evaluated, levels serum blister fluid were assessed by enzyme‐linked immunosorbent assay (ELISA). Results Prolactin significantly P < 0.01) elevated psoriatic lesional skin. Correlations between PASI different non‐lesional skin...

Abstract Objectives Information on prevalences of pediatric dermatoses in Egypt is scanty. This study aimed to supplement existing data. Methods A cross‐sectional was conducted Damietta, between October 2011 and March 2012. It involved 6162 pupils randomly selected from 30 primary schools. The sample equally divided (3081 pupils/15 schools) urban rural areas. Each participant interviewed for age, gender, residence complaint. Hygiene status evaluated a clinical examination carried out skin...

Information on patterns of skin diseases in Egypt is scanty.The medical records patients attending dermatology outpatient clinics at Ain Shams University Hospitals from January 2001 to December were retrieved. Valid data 7528 included the study. Demographic (age and sex) diagnoses disease extracted, coded, analyzed.Patients' attendance revealed mean age 23.5 ± 15.6 years female predominance a male ratio 1.6:1. Most presented summer (40.7%). Infections constituted most dermatoses (45.4%),...

Background/purpose: The value of psoriatic plaques pretreatment with specific topical preparations in the setting NB‐ultraviolet‐B (UVB) therapy is debatable. It may be clarified through a comparative assessment between crude coal tar and petrolatum as candidates. Methods: A prospective study included 40 patients plaque psoriasis undergoing NB‐UVB therapy. We compared among three treatment regimens: alone (control group; n =20) well preceded by 3% on one side other (cases group I II; =20)....

Summary Background Striae distensae ( SD ), a type of dermal scarring, are psychologically disappointing. To date, information and scientific research behind the role hormonal factors in development still unclear. It is vital to understand striae offer patients best therapeutic options. Objectives investigate early alterations regarding expression estrogen, androgen, glucocorticoid receptors (estrogen receptor ER androgen AR GR ) skin samples multigravida MG nulligravida NG cases compare...

Abstract Not only macrophages, T‐helper (Th)1 and Th2 , but also CD 4 + 25 high FoxP3 regulatory T cells (T‐regs) are involved in immune response to Mycobacterium leprae . We aimed evaluate serum interleukin ( IL )‐1 β ‐12p70 (macrophage cytokines), interferon‐ γ IFN ‐ ) (Th1 cytokine), ‐4 (Th2 cytokine) circulating T‐regs, untreated leprosy patients. Forty three patients 40 controls were assessed for the mentioned cytokines using ELISA Patients T‐regs flow cytometry. subgrouped into...

Abstract: There are several reports of an association between ichthyosis and rickets based mainly on a causative relationship through the impaired ability ichthyotic skin to synthesize vitamin D. Hypocalcemic D‐resistant represents specific type that is attributed D receptor defect rather than deficiency. Nevertheless, extremely rare bullous congenital ichthyosiform erythroderma hypocalcemic presented.

Recent accumulating data in the literature have indicated a complex photoprotective role of epidermis, and melanin as major epidermal mechanism has become debatable.Comparative assessment roles played by different structures compounds.In total, 64 participants, comprising patients with vitiligo (n = 32) healthy volunteers 32), skin phototypes (SPTs) II to V, were enrolled study. Areas delineated; for both lesional nonlesional skin, stratum corneum (the SC) was stripped, followed 24 h later...

S100B protein was reported to be elevated in psoriatic patients' serum, with no previous evaluation of its skin expression, contrast the extensively studied S100 protein.To evaluate serum level and expression psoriasis assess possible involvement pathogenesis.Serum estimated 40 patients different clinical varieties 10 healthy controls. assessed immunohistochemically lesional non-lesional normal Relation disease severity also evaluated.Serum significantly higher (0.15±0.03 µg/l) than controls...

Journal Article Endothelin‐1 is significantly elevated in plasma of patients with vitiligo treated psoralen plus ultraviolet A Get access M. B. Abdel‐Naser, Abdel‐Naser Departments Dermatology, Venereology and Andrology, Clinical Pathology, Ain Shams University, Cairo, Egypt Dr med. Badawy MD, 4 Al Rahman Tower, El Sawah Sq. 11281 Egypt. E‐mail: abdelnasermb@yahoo.com Search for other works by this author on: Oxford Academic Google Scholar E. A. El‐Khateeb, El‐Khateeb T. H. Sallam, Sallam...

Abstract Background Leprosy is a chronic, infectious disease caused by Mycobacterium leprae. It mainly affects the skin, peripheral nerves, mucosa of upper respiratory tract, and eyes. Nerve damage may result in lack ability to feel pain, which can lead loss parts person's extremities from repeated injuries or infection due unnoticed wounds. Egypt one first countries region achieve elimination target at national level as early 1994, However still endemic certain foci Egypt. Thus, our study...

Abstract Background Introduction: The COVID-19 pandemic, declared by the World Health Organization in 2020, prompted numerous restrictions and changes healthcare practices globally. In Egypt, measures such as curfews, closure of public places, suspension schools universities were implemented. These had significant implications for delivery, including dermatology services. Aim Work This study aimed to investigate effect pandemic on pattern skin diseases Egypt. Patients Methods Data from...

Abstract Background Male factor plays a role in about 50% of infertility cases world-wide. This may be attributed to pretesticular, testicular, post testicular causes or it idiopathic. Psychological disorders including depression are being investigated as one the risk factors responsible for idiopathic with contradicting reports. Aim The aim this study is assess potential impact on semen parameters and evaluate improving score these parameters. Patients Methods prospective observational...

Abstract Background Vitiligo is a common autoimmune disease of skin depigmentation. The presents with many challenges, such as progression, resistance to treatment and recurrence. Recent studies reported possible role IL-15 in the pathogenesis, activity recurrence disease. Objective Evaluation tissue serum levels non-segmental vitiligo patients. Methods This Case-control study included 31 participants; 20 patients 11 controls. In patient group, we took samples three punch biopsies (3mm) from...

Abstract Background Capillaroscopy is a non-invasive technique which allows direct, in vivo imaging of skin microcirculation to detect microvascular abnormalities. An important association psoriasis metabolic syndrome, with prevalence 40% psoriatic patients. Metabolic syndrome multiplex risk factor that arises from insulin resistance accompanying abnormal adipose deposition and function. Patients have an increased for cardiovascular diseases atherosclerosis. Aim the Work Describe morphology,...

Summary Background Natural ultraviolet exposure induces hair damage, which is difficult to avoid. Most of the research work focused on effect epidermis, dermis as well immune system, whereas long‐term has not been investigated. Aim: we performed our experiment find out changes induced in follicle and shaft those patients exposed high doses (A B) during treatment other skin conditions. Patients Methods Light transmission electron microscopy examination scalp follicles shafts 10 with vitiligo...

Genital warts caused by human papillomavirus (HPV) are one of the most common sexually transmitted infections. Long latency, lesions' multiplicity, high recurrence rate, and tendency to malignant transformation essential challenges during management. Traditional treatment modalities known be lesion-directed while intralesional immunotherapy was introduced act beyond individual lesions confront previous through injection antigens, such as measles, mumps rubella (MMR) vaccine, stimulate immune...

Abstract Background Up to 30% of male infertility may be idiopathic. Researchers are looking into psychological problems, particularly depression, as possible risk factors for such idiopathic etiology. We aimed assess how depression affects Egyptian patients’ semen parameters and its indicators fertility evaluate the potential positive influence improving score on these parameters. A prospective observational pilot clinical study included twenty-one patients with moderate, severe, or very...

Background. Recent accumulating data in the literature indicates a complex photoprotective role of epidermis where melanin as major mechanism has become debatable. Aim. To make comparative assessment roles played by different epidermal structures. Methods. 40 patients with vitiligo, skin phototypes (SPTs) II to V, were enrolled study. Areas (lesional and nonlesional) delineated stratum corneum (SC) was stripped from half each area obtain 4 models: lesional, lesional stripped, nonlesional,...

Abstract Background Genital warts caused by human papillomavirus (HPV) are one of the most common sexually transmitted infections, especially among women. HPV infection has a relatively long incubation period up to 8 months. It is known have high recurrence rate, and certain high-risk strains be associated with malignancies cervix, penis, vulva, vagina, anus. Thus, factors such as latency, lesions’ multiplicity, tendency malignant transformation, essential challenges during management...

Abstract Background Teledermatology (TD) is one of the most rapidly evolving branches telemedicine. It uses information and communications technologies to diagnose, monitor, treat, prevent, research, educate over a distance. was demonstrated be more efficient cost effective in certain settings, such as travel times. reported reliable diagnostically accurate for variety dermatologic complaints shown reduce wait times, increase access, improve patient satisfaction quality life. Aim Work...