A5049149933- Physiological and biochemical adaptations
- Fish Ecology and Management Studies
- Ocean Acidification Effects and Responses
- Aquaculture Nutrition and Growth
- High Altitude and Hypoxia
- Aquaculture disease management and microbiota
- Mitochondrial Function and Pathology
- Coral and Marine Ecosystems Studies
- Adipose Tissue and Metabolism
- Marine Bivalve and Aquaculture Studies
- Zebrafish Biomedical Research Applications
- Environmental Toxicology and Ecotoxicology
- Fish biology, ecology, and behavior
- Cancer-related molecular mechanisms research
- Marine and fisheries research
- Cancer, Hypoxia, and Metabolism
- Identification and Quantification in Food
- Metabolomics and Mass Spectrometry Studies
- Water Quality Monitoring Technologies
- Climate Change and Health Impacts
- MicroRNA in disease regulation
- Nitric Oxide and Endothelin Effects
- Climate variability and models
- Genomics and Phylogenetic Studies
- Neuroscience of respiration and sleep
University of Oslo
2014-2025
Can Tho University
2010-2015
Aarhus University
2008-2014
University of Washington
2014
With the occurrence of global change, research aimed at estimating performance marine ectotherms in a warmer and acidified future has intensified. The concept oxygen- capacity-limited thermal tolerance, which is inspired by Fry paradigm bell-shaped increase–optimum–decrease-type response aerobic scope to increasing temperature, but also includes proposed negative synergistic effects elevated CO2 levels, been suggested as unifying framework. objectives this meta-analysis were assess...
Some recent modelling papers projecting smaller fish sizes and catches in a warmer future are based on erroneous assumptions regarding (i) the scaling of gills with body mass (ii) energetic cost 'maintenance'. Assumption posits that insurmountable geometric constraints prevent respiratory surface areas from growing as fast volume. It is argued these explain allometric energy metabolism, whereby larger fishes have relatively lower mass-specific metabolic rates. concludes when reach certain...
Ocean acidification poses a range of threats to marine invertebrates; however, the potential effects rising carbon dioxide (CO2) on invertebrate behaviour are largely unknown. Marine gastropod conch snails have modified foot and operculum allowing them leap backwards rapidly when faced with predator, such as venomous cone shell. Here, we show that projected near-future seawater CO2 levels (961 µatm) impair this escape during predator-prey interaction. Elevated-CO2 halved number jumped from...
Abstract To address how capacity for oxygen transport influences tolerance of acute warming in fishes, we investigated whether a reduction haematocrit, by means intra-peritoneal injection the haemolytic agent phenylhydrazine, lowered upper critical temperature sea bass. A haematocrit from 42±2 to 20±3% (mean ± s.e.m.) caused significant but minor temperature, 35.8 0.1 35.1±0.2°C, with no correlation between individual values and thermal limit. Anaemia did not influence rise uptake 25 33°C,...
ABSTRACT Recent studies suggest that projected rises of aquatic CO2 levels cause acid–base regulatory responses in fishes lead to altered GABAergic neurotransmission and disrupted behaviour, threatening fitness population survival. It is thought changes Cl− HCO3− gradients across neural membranes interfere with the function GABA-gated anion channels (GABAA receptors). So far, such alterations have been revealed experimentally by exposing species living low-CO2 environments, like many oceanic...
Connectivity of coral reef fish populations relies on successful dispersal a pelagic larval phase. Pelagic larvae must exhibit high swimming abilities to overcome ocean and currents, but once settling onto the reef, transition endure habitats that become hypoxic at night. Therefore, rapidly dramatically shift their physiology over short period time. Taking an integrative, physiological approach, using respirometry, examining hypoxia tolerance transcriptomics, we show cinnamon anemonefish (...
The anoxia-tolerant crucian carp (Carassius carassius) has been studied in detail for numerous years, with particular focus on unravelling the underlying physiological mechanisms of anoxia tolerance. However, relatively little work focused what occurs beyond anoxia, and often is a single organ or tissue type. In this study, we quantified more than 100 metabolites by capillary electrophoresis-mass spectrometry (CE-MS) brain, heart, liver, blood plasma from four experimental groups, being...
Abstract Crucian carp ( Carassius carassius ), a member of the family (Cyprinidae), is known for its remarkable anoxia tolerance. The physiological responses and adaptations to are well documented, but there need better understanding molecular regulation evolutionary mechanisms behind these adaptations. Here we present high-quality, functionally annotated, chromosome-level genome assembly that can facilitate such further studies. Genomic DNA was obtained from wild-caught crucian specimen...
Background: Extreme anoxia tolerance requires a metabolic depression whose modulation could involve small non-coding RNAs (small ncRNAs), which are specific, rapid, and reversible regulators of gene expression. A previous study sncRNA expression in embryos the annual killifish Austrofundulus limnaeus, most anoxia-tolerant vertebrate known, revealed specific pattern sncRNAs that play important roles tolerance. Here, we conduct comparative on presence ncRNAs representatives several major...
Crucian carp (Carassius carassius) survive without oxygen for several months, but it is unknown whether they are able to protect themselves from cell death normally caused by the absence, and particularly return, of oxygen. Here, we quantified in brain tissue crucian exposed anoxia re-oxygenation using terminal deoxy-nucleotidyl transferase dUTP nick-end labelling (TUNEL) assay, proliferation immunohistochemical staining proliferating nuclear antigen (PCNA) as well PCNA mRNA expression. We...
ABSTRACT Just over two decades ago, Bob Boutilier published a much-cited Review in this journal on the mechanisms of cell survival hypoxia and hypothermia. Here, we celebrate important by describing how our knowledge behind anoxia tolerance have progressed since 2001, including new key roles mitochondria, something had started exploring. Evidence now suggests that, anoxia-tolerant brains, mitochondria initiate responses aimed at suppressing electrical activity energy use. These are largely...
Oxygen uptake ( ) and critical oxygen tension P crit were measured in resting perch Perca fluviatilis that either fasting or digesting. Digestion caused to double (from 61 117 mg O 2 kg −1 h was associated with a rise 3·4 4·9 kPa), showing the animal's digestive state must be considered when assessing effect of hypoxia natural conditions, defining optimal conditions aquaculture.