A5002842847- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Rheumatoid Arthritis Research and Therapies
- Reproductive Biology and Fertility
- Sex work and related issues
- Sperm and Testicular Function
- Ovarian function and disorders
- Chinese history and philosophy
- Hepatitis B Virus Studies
- HIV Research and Treatment
- Hormonal and reproductive studies
- Electrochemical Analysis and Applications
- Analytical chemistry methods development
- Palliative Care and End-of-Life Issues
- Monoclonal and Polyclonal Antibodies Research
- Hepatitis C virus research
- Peroxisome Proliferator-Activated Receptors
- Adolescent Sexual and Reproductive Health
- HIV/AIDS drug development and treatment
- HER2/EGFR in Cancer Research
- Bone Metabolism and Diseases
- Spectroscopy and Quantum Chemical Studies
- Soil erosion and sediment transport
- Patient Dignity and Privacy
- S100 Proteins and Annexins
Nanjing Medical University
2016-2025
Nanjing General Hospital of Nanjing Military Command
2016-2025
Nanjing University
2016-2025
Tsinghua University
2015-2025
Guizhou Normal University
2021-2024
Sichuan University
2022-2023
State Key Laboratory of Reproductive Medicine
2023
Beijing Institute of Graphic Communication
2023
Wuhan Ship Development & Design Institute
2013-2022
Hunan University of Technology
2022
High-fat diet (HFD)-induced metabolic disorders can lead to impaired sperm production. We aim investigate if HFD-induced gut microbiota dysbiosis functionally influence spermatogenesis and motility.Faecal microbes derived from the HFD-fed or normal (ND)-fed male mice were transplanted maintained on ND. The microbes, count motility analysed. Human faecal/semen/blood samples collected assess microbiota, quality endotoxin.Transplantation of HFD into ND-maintained (HFD-FMT) resulted in a...
Anti-malarial drug artesunate can suppress inflammation and prevent cartilage bone destruction in collagen-induced arthritis model rats—suggesting it may be a potent for rheumatoid (RA) therapy. We aimed to investigate its effect on the invasive property of fibroblast-like synoviocytes (FLS) from patients with RA. Synovial tissues were obtained by closed needle biopsy active RA patients, FLS isolated cultured vitro. RA-FLS treated at various concentrations, while methotrexate or...
Aim To investigate the impact of short-course tocilizumab (TCZ) on hepatitis B virus (HBV) reactivation in rheumatoid arthritis (RA) patients. Methods RA patients with moderate to high disease activity, at least one feature poor prognosis and inadequate response conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) were recruited. Three consecutive doses intravenous TCZ given combined csDMARDs. Liver function HBV infection status evaluated baseline, weeks 4, 8 12. Results...
Background: Epidemiological evidence remains equivocal on the associations between environmentally relevant levels of per-/polyfluoroalkyl substances (PFASs) and human semen quality. Objectives: We aimed to test whether potential effects quality could be better observed when seminal PFAS were used as an exposure marker compared with serum levels. Methods: Matched samples from 664 adult men collected a cross-sectional population in China 2015 2016. Multiple parameters assessed, along...
Eight species of tree crickets are reviewed from China including Oecanthus antennalis, O. euryelytra, longicauda, similator, turanicus, zhengi, oceanicus He sp. nov. and Xabea levissima. Calling songs COI genes all compared. Keys to given by morphology songs. New is posited in Museum Biology, East Normal University (ECNU). The state sinensis discussed. latipennis Liu, Yin Xia, 1994 a junior homonym Riley, 1881.
While the world has watched 20 years of unfolding misery in sub-Saharan Africa, Chinese AIDS epidemic been steadily gathering momentum. Because China9s enormous population and growing importance global economy, an could have serious repercussions. Kaufman Jing say that China unique opportunity to learn from mistakes accumulated wisdom last years. The government9s recent willingness tackle HIV problem is encouraging, but authors this Policy Forum argue battle must be fought at local level,...
By September 2016, approximately 653,865 people in China were living with HIV/AIDS (PLWHA) and 492,725 receiving antiretroviral therapy (ART). PLWHA frequently experience discrimination all domains of their personal social lives. The World Health Organization includes its list determinants health factors that have been linked to poor physical psychological health. This paper identifies the family support enjoyed faced by infected HIV examines effect they on patients' quality life (QOL) as...
Cancer is the second leading cause of death globally, causing a substantial economic burden on cancer suffers and their families. The aim this study to explore prevalence, determinants consequences catastrophic health expenditure (CHE) among urban rural end-of-life (EOF) patients in China. Using respondent-driven sampling face-to-face interviews, field research was conducted with specialist questionnaire. Data were collected 792 who died between June 2013 2016 household identified by...
Many factors may lead to sperm DNA damage. However, it is little known that the correlations of damage with obesity-associated markers, and reproductive hormones lipids levels in serum seminal plasma. In our prospective study, a total 1 010 subfertile men, aged from 18 50 years old, were enrolled August 2012 through June 2015. Their semen parameters, acrosomal enzyme activity, plasma biochemical detected. Sperm fragmentation index (DFI) was determined by chromatin structure assay. The...
Vitamin D deficiency is a common health issue around the world. We therefore evaluated associations of semen quality with both serum and seminal plasma vitamin levels studied mechanisms underlying these by incubating spermatozoa 1,25(OH)2D in vitro. Two hundred twenty-two men were included our study. was detected using an electrochemiluminescence method. Spermatozoa used for vitro experiments isolated density gradient centrifugation. Positive relationships 25(OH)D volume fructose identified....
Abstract Abnormal lipid/lipoprotein metabolism induced by obesity may affect spermatogenesis inhibiting testosterone synthesis in Leydig cells. It is crucial to determine which components of lipoproteins inhibit synthesis. Circulating oxidized low-density lipoprotein (oxLDL), the form LDL, has been reported be an independent risk factor for decreased serum levels. However, whether oxLDL a damaging effect on cell function and detailed mechanisms have rarely studied. This study first showed...
Blood-testis barrier (BTB) damage promotes spermatogenesis dysfunction, which is a critical cause of male infertility. Dyslipidemia has been correlated with infertility, but the major hazardous lipid and underlying mechanism remains unclear. In this study, we firstly discovered an elevation palmitic acid (PA) decrease inhibin B in patients severe dyszoospermia, leaded us to explore effects PA on Sertoli cells. We observed BTB by PA. penetration endoplasmic reticulum (ER) its ER structures...
Polycystic ovary syndrome (PCOS) is a common reproductive endocrine disorder that frequently exhibits low-grade inflammation, pro-oxidant activity, and gut dysbiosis. PCOS has become one of the leading causes female infertility worldwide. Recently, omega-3 polyunsaturated fatty acids (PUFAs) have been proven to benefit metabolic disorders in patients. However, its roles regulation endocrinal balances pathophysiology are not clear. In present study, we aimed explore how PUFAs alleviate...
This work presents a revision of genus Xizicus, two new subgenera are described: Xizicus (Zangxizicus) subgen. nov. and (Haploxizicus) Three species described, namely (Paraxizicus) fallax sp. nov., tibeticus quadrifascipes nov.. Keys to provided.