A5020934529- Nutrition and Health in Aging
- Cystic Fibrosis Research Advances
- Frailty in Older Adults
- Clinical Nutrition and Gastroenterology
- Alkaline Phosphatase Research Studies
- Esophageal and GI Pathology
- Vitamin D Research Studies
- Heterotopic Ossification and Related Conditions
- Parathyroid Disorders and Treatments
- Nutritional Studies and Diet
- Child Nutrition and Water Access
- Body Composition Measurement Techniques
- Diet and metabolism studies
- Biochemical and Molecular Research
- Genomics, phytochemicals, and oxidative stress
- Bone health and osteoporosis research
- Childhood Cancer Survivors' Quality of Life
- Dietary Effects on Health
- Child Nutrition and Feeding Issues
- Selenium in Biological Systems
- Pancreatitis Pathology and Treatment
- Gut microbiota and health
- Folate and B Vitamins Research
- Bone and Joint Diseases
- Obesity, Physical Activity, Diet
Instituto de Investigación Biosanitaria de Granada
2021-2024
Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable
2023-2024
Instituto de Salud Carlos III
2023-2024
Hospital Regional Universitario de Málaga
2015-2021
Instituto de Investigación Biomédica de Málaga
2015-2021
Universidad de Málaga
2015-2021
Protein-calorie malnutrition is very frequent in cancer patients and associated with an increase morbidity mortality. Recently, the Global Leadership Initiative on Malnutrition (GLIM) criteria were proposed to standardize diagnosis of malnutrition. Nevertheless, these not validated prospective studies. Our objective determine prevalence inpatients using different diagnostic classifications, including GLIM criteria, establish their association length stay Hence, we designed a study. Within...
Anxiety and depression are a common issue in patients with cancer, yet understudied among hospitalized patients. The aim of this study was to estimate the prevalence anxiety symptomatology cancer inpatients its relationship malnutrition.Cross-sectional A nutritional assessment done using Global Leadership Initiative on Malnutrition (GLIM) criteria diagnose malnutrition. Data regarding obtained Hospital Depression Scale (HADS).A total 282 were assessed. GLIM found 20% (66) well-nourished 80%...
Our objective was to evaluate the clinical application of third lumbar vertebra (L3)-computer tomography (CT)-determined sarcopenia as a marker muscle mass in cancer inpatients diagnosed with malnutrition according Global Leadership Initiative on Malnutrition (GLIM) criteria and establish its association 6-month mortality.This an observational, prospective study patients from inpatient oncology unit. We performed nutritional assessment GLIM criteria, including cross-sectional area at L3 by...
Since the prevalence of hypophosphatasia (HPP), a rare genetic disease, seems to be underestimated in clinical practice, this study, new diagnostic algorithm identify missed cases HPP was developed and implemented.
Hypophosphatasia (HPP) is an inborn metabolic error caused by mutations in the ALPL gene encoding tissue non-specific alkaline phosphatase (TNSALP) and leading to decreased (ALP) activity. Although main characteristic of this disease bone involvement, it presents a great genetic clinical variability, which makes systemic disease. Patients were recruited based on biochemical assessments. Diagnosis was made measuring serum ALP pyridoxal 5-phosphate levels finally Sanger sequencing from...
Background: The use of oral nutritional supplements (ONS) is common practice in patients suffering from cystic fibrosis (CF). We aimed to describe the rate ONS assess their contribution dietary intake and determine if they are associated with respiratory status, body composition, muscle strength, bone mineral density (BMD), remodeling biomarkers, plasmatic levels vitamins. Methods: Cross-sectional study. Patients were clinically stable adults recruited CF unit. A 4-day prospective...
Sarcopenia has recently been recognized as a complication of diabetes. However, there are few results about the prevalence sarcopenia and dynapenia related clinical outcomes in type 1 diabetes mellitus (T1DM). Our objectives were to evaluate determine whether any associations with disease-related factors people T1DM. A cross-sectional study was conducted We assessed appendicular skeletal mass index (ASMI) using bioimpedance 50 Hz (Nutrilab Akern). Muscle function through handgrip strength...
Loss of fat-free mass (FFM) is associated with an increase in morbidity and mortality cystic fibrosis (CF) patients. Handgrip strength (HGS) measures muscle function may be clinical parameters prognostic value. Our objectives were to evaluate through HGS CF patients determine if there are any associations respiratory variables, FFM, bone mineral density (BMD).A cross-sectional study conducted clinically stable We evaluated HGS, function-forced expiratory volume 1 s (FEV1) (%), forced vital...
Abstract The prevalence of osteopenia/osteoporosis has not been sufficiently studied in people with bronchiectasis due to cystic fibrosis (BC), nor its relationship other variables (clinical, body composition and bone turnover inflammation markers) studied. Our aim was determine the osteopenia osteoporosis related factors patients BC. We did a cross-sectional study BC clinically stable state. Spirometric parameters, annual exacerbations analysis markers (BTM) were evaluated. Densitometry...
Introduction: few studies have evaluated body composition (BC) through different techniques, and the degree of agreement between them in adults with cystic fibrosis (CF). Objectives: to describe BC using techniques assess nutritional status test their concordance CF. Methods: a cross-sectional study CF patients clinically stable situation. Nutritional assessment was performed skinfold measurement (SM) densitometry (DXA). Fat-free mass index (FFMI) also determined. The diagnosis malnutrition...
We present a case of severe acute pancreatitis induced by hypertriglyceridemia secondary to lipoprotein lipase (LPL) deficiency in pregnant patient with gestational diabetes, initially maneged diet but it was later necessary carry out artificial nutricional support measures: total parenteral nutrition. LPL might cause hypertriglyceridemia, repetition which is an unwieldy and situation during pregnancy. Acute familial accounts for 5% cases, including deficiency. The goal treatment reach...
Hypophosphatasia (HPP) a rare disease caused by mutations in the ALPL gene encoding for tissue-nonspecific alkaline phosphatase protein (TNSALP), has been identified as potentially under-diagnosed condition worldwide which may have higher prevalence than currently established. This is largely due to overlapping of its symptomatology with that other more frequent pathologies. Although HPP usually associated deficient bone mineralization, high genetic variability results clinical...