A5030233633- Vasculitis and related conditions
- Lymphoma Diagnosis and Treatment
- Poxvirus research and outbreaks
- Bacillus and Francisella bacterial research
- Systemic Lupus Erythematosus Research
- Herpesvirus Infections and Treatments
- Bladder and Urothelial Cancer Treatments
- COVID-19 and healthcare impacts
- Chronic Lymphocytic Leukemia Research
- Pregnancy and preeclampsia studies
- Urologic and reproductive health conditions
- Multiple Myeloma Research and Treatments
- Medical Imaging and Pathology Studies
- Cell Adhesion Molecules Research
- Cancer-related gene regulation
- Hedgehog Signaling Pathway Studies
- Lung Cancer Diagnosis and Treatment
- Prenatal Screening and Diagnostics
- Renal cell carcinoma treatment
- Cancer Research and Treatments
- COVID-19 Clinical Research Studies
- Colorectal Cancer Surgical Treatments
- Radiomics and Machine Learning in Medical Imaging
- Viral-associated cancers and disorders
- Birth, Development, and Health
NorthShore University HealthSystem
2022-2024
University of Chicago
2022-2024
Cleveland Clinic
2022
The University of Texas Southwestern Medical Center
2022
Indiana University – Purdue University Indianapolis
2022
Aortitis is an uncommon cause of aortic aneurysms. Arterial inflammation can lead to irreversible vascular damage. Early recognition necessary for treatment prevent permanent consequences vessel inflammation.
Background: The histopathology and CD15 expression in large for gestational age (LGA) placentas is not well-documented. Methods: To analyze this, we utilized 2 separate cohorts of from singleton term deliveries. LGA appropriate (AGA) were compared major histopathologies including acute chronic inflammation, maternal fetal vascular malperfusion, delayed villous maturation (DVM), hypervascularity/chorangiosis. We also examined immunohistochemistry AGA placentas. Stained slides reviewed blinded...
The NKX3.1 immunohistochemical stain is widely recognized as a highly sensitive and specific marker for prostate adenocarcinoma. Nevertheless, its expression has been documented in various nonprostatic tissues malignancies. This review aims to provide an overview of diverse tumor types, with focus on aberrant esophageal/gastroesophageal adenocarcinoma (E/GE-ADC). In our investigation, we explored the series E/GE-ADC shed light prevalence this category. A total 50 samples, comprising primary...
Abstract Monkeypox is a rare zoonotic DNA virus with lineage from the Poxviridae family, Chordopoxvirinae subfamily, and Orthopoxvirus genus. (1) With previous history of controlled contained occasional outbreaks virus, currently widely erupted outbreak monkeypox progressively rising numbers has been reported since May 2022 in multiple countries western hemisphere that are not historically endemic for this infection, particularly UK EU countries. The global cessation smallpox vaccination...
In this case, we describe the potential risk of developing an infectious complication leading to a secondary malignancy after short course immunotherapy. We report patient who presented with Epstein-Barr virus (EBV) driven Hodgkin's lymphoma treatment daratumumab along pomalidomide and dexamethasone for relapsed multiple myeloma. Although there have been limited documented cases EBV reactivation, in patients presenting symptoms or neutropenia on daratumumab-based regimen, testing should not...
Abstract Background Tuberculosis (TB) is a communicable disease, transmitted almost exclusively by cough aerosols carrying pathogens of the M. tuberculosis complex. TB continues to be major public health threat, causing an estimated 10.4 million new cases and 1.3 deaths from globally in 2016. Many more people may have latent infection (LTBI), which go undetected without further laboratory investigation. The Quantiferon-TB Gold Plus (QFT-Plus) Interferon Gamma Release Assay (IGRA) for...
Introduction: Epstein Barr Virus (EBV) is a herpesvirus commonly disseminated via oropharyngeal/nasopharyngeal secretions. It classically presents as fever, pharyngitis, lymphadenopathy (LAD), and fatigue. Rarely, patients develop cholestatic/hepatocellular (mixed) liver injury, splenic infarcts (SI) terminal ileitis (TI). We describe such case here. Case Description/Methods: 26 year old woman with no past medical history presented to the hospital (w/) one week of nausea, bilateral upper...
Abstract Introduction/Objective GLI1 encodes a transcription factor that targets cell cycle regulators affecting stem proliferation. Activation of the GLI (glioma-associated oncogene homologue 1). activity in adult tissues is restricted but has been identified various neoplasms, as result mutations PTCH (patched) or SMOH (smoothened) genes, encoding components sonic hedgehog pathway, by amplification GLI. The B-actin (ACTB) gene, an essential cytoskeletal component, under control conserved,...
The pathologic assessment of colorectal carcinoma specimens plays a crucial role in the therapeutic management patients and disease prognostication. TNM staging system is used globally critical component pathology reporting. However, our experience informs us that there are significant variations assignment stage, both between pathologists hospital centers. We identify several potential reasons for this, among them suboptimal gross microscopic resection and, later, nonuniformity applying...