A5100362947- Liver Disease Diagnosis and Treatment
- Diet, Metabolism, and Disease
- Hepatitis B Virus Studies
- Cancer and Skin Lesions
- Dysphagia Assessment and Management
- Pancreatic function and diabetes
- Systemic Lupus Erythematosus Research
- Dermatology and Skin Diseases
- Artificial Intelligence in Healthcare
- Adolescent Sexual and Reproductive Health
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Nail Diseases and Treatments
- Soft tissue tumor case studies
- Gout, Hyperuricemia, Uric Acid
- Liver Diseases and Immunity
- Electroconvulsive Therapy Studies
- Mesenchymal stem cell research
- Tracheal and airway disorders
- Retinoids in leukemia and cellular processes
- Crime Patterns and Interventions
- Cervical Cancer and HPV Research
- Cancer Cells and Metastasis
- Nasal Surgery and Airway Studies
- Obstructive Sleep Apnea Research
- Skin Diseases and Diabetes
West Anhui University
2024
The First Hospital of Changsha
2023
Soochow University
2023
Wuxi Ninth People's Hospital
2023
Liaocheng People's Hospital
2023
Nanjing University of Chinese Medicine
2023
Xuzhou Medical College
2020
Chinese Institute for Brain Research
2019
Beijing Normal University
2019
ShenZhen People’s Hospital
2019
Abstract Tagraxofusp-erzs (Elzonris, Stemline) is a cytotoxin that targets CD123-expressing cells. On December 21, 2018, FDA approved tagraxofusp-erzs for the treatment of blastic plasmacytoid dendritic cell neoplasms (BPDCN) in adult and pediatric patients 2 years older. Approval was based on response rate single-arm trial, Study STML-401-0114; pivotal cohort included 13 with treatment-naïve BPDCN who received monotherapy. The complete or clinical (CR/CRc) 54% (95% CI: 25%–81%), median...
To determine whether the uric acid/high‑density lipoprotein cholesterol ratio (UHR) is associated with visceral fat area (VFA) in patients type 2 diabetes mellitus (T2DM).Participants aged 18-70 years a diagnosis of T2DM were recruited from National Metabolic Management Center January 2020 to July 2022. Medical data collected for all participants included medical history, general measures, carotid intima-media thickness, abdominal VFA, and subcutaneous (SFA). The divided into groups...
<i>Background:</i> Erythema toxicum neonatorum (ETN) is a very common disease, but its predisposing factors are still unknown. <i>Objective:</i> To determine the of ETN. <i>Methods:</i> Seven hundred and eighty-three neonates born in same hospital during period were investigated, to ETN evaluated case-control study. <i>Results:</i> (1) The incidence about 43.68%, it significantly higher males than females (p < 0.001). (2) Term birth 0.05),...
Persistent high-risk human papillomavirus (HPV) infection is correlated with an increased risk of developing intraepithelial lesion or malignancy (NILM). The aims the current study to establish a method named BioPerfectus Multiplex Real Time (BMRT) HPV assay for simultaneous typing and quantifying HPVs, evaluate it by comparison GenoArray test PCR-sequencing method, as well histological status. A total 817 cervical specimens were evaluated BMRT test, using reference standard; simultaneously,...
Objective: Few studies have investigated the effects of dexmedetomidine (DEX) on breastfeeding after cesarean delivery. A randomized double-blind controlled trial was conducted to investigate whether administration DEX, immediately delivery and for patient-controlled intravenous analgesia (PCIA), can be beneficial breastfeeding. Patients Methods: One hundred sixty parturients scheduled elective section under spinal anesthesia were randomly allocated DEX group (a loading dose pumped at 0.5...
C-X-C-chemokine ligand 13 (CXCL13), the for C-X-C chemokine receptor type 5 (CXCR5), is a major regulator of B-cell trafficking and plays an integral role in age-dependent clearance hepatitis B virus (HBV) mouse model. However, expression function CXCL13 patients with chronic (CHB) remain unknown. By use liver cell subpopulations isolated from CHB patients, we found that mRNA was abundantly expressed Kupffer cells (KCs), but not primary hepatocytes, sinusoidal endothelial cells, hepatic...
Abstract Background: Although metabolomic analysis for patients with nonalcoholic fatty liver disease (NAFLD) was a promising approach to identify novel biomarkers as targets the diagnosis of NAFLD, serum metabolomics profile early-stage NAFLD from central China remain unknown. Objective: The aim present study explore metabolic characteristics based on ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) technology, differential metabolites and perform functional...
Many studies have confirmed the positive effects of comprehensive sexuality education on development children’s sexuality, such as acquisition sexual health knowledge. However, little is known about impact social development, although several core aspects approach stress concepts fairness, respect and equality. This study examined whether could weaken effect in-group bias decision-making towards friends strangers. Compared to students in a control group, who never received education, we...
<b><i>Background:</i></b> Multiple cutaneous piloleiomyomas are rare, frequently painful and difficult-to-treat benign tumours originating in the arrectores pilorum muscles of hair follicles. <b><i>Objective:</i></b> The aim this study was to determine efficacy a local injection triamcinolone acetonide relieving piloleiomyoma-related pain. <b><i>Methods:</i></b> A patient with multiple treated weekly injections into...
Our previous work showed that tumor necrosis factor (TNF)-α and FasL induce apoptosis of anterior pituitary cells. To further analyze the effect these proapoptotic factors, we infected primary cultures from rat pituitary, GH3 AtT20 cells with first-generation adenoviral vectors encoding TNF-α, or, as a control, β-galactosidase (β-Gal), under control human cytomegalovirus promoter. Successful expression encoded transgenes was determined by immunocytochemistry. Although observed basal TNF-α in...
Systemic lupus erythematosus (SLE) is an autoimmune disease with abnormal apoptosis and autoantibody production. Calcitonin gene-related peptide (CGRP) a neuropeptide produced by the central peripheral nervous systems endocrine cells. It can influence cell death in thymocytes cultured smooth muscle cells, inhibits production of interleukin (IL)-2, which apoptosis.To investigate effects calcitonin on blood mononuclear cells (PBMCs) from patients SLE.The percentage PBMCs SLE healthy donors...
<b><i>Background:</i></b> No optimal regimen exists for the LPNYL (long-pulsed 1,064-nm neodymium:yttrium-aluminum-garnet laser) treating onychomycosis. <b><i>Objective:</i></b> To establish an treatment onychomycosis caused by <i>Trichophyton rubrum</i> (OCTr). <b><i>Patients and Methods:</i></b> First, 511 infected nails of 177 patients were treated using with orthogonally designed regimens according to...
The present study aimed to examine the neurophysiological mechanisms of 2,6-diisopropylphenol and N-methyl-D-aspartate (NMDA) receptor antagonist against learning memory impairment, induced by electroconvulsive therapy (ECT). A total 48 adult depressed rats without olfactory bulbs were randomly divided into six experimental groups: i) saline; ii) 10 mg/kg MK‑801; iii) MK‑801 a course ECT; iv) 200 2,6‑diisopropylphenol; v) 2,6‑diisopropylphenol vi) saline ECT. abilities assessed using Morris...
Abstract The objective of this study was to investigate the relationships image texture properties with chewing behaviors, and mechanical during mastication bread. Gray-level gradient co-occurrence matrix (GGCM) used process images boluses. behaviors were recorded by electromyography (EMG), measured analyzer. results showed that among features, inverse difference moment (IDM GGCM ) selected as main parameter describe decomposition IDM positively related weight gain ( r = 0.865, p < 0.01),...
The widespread use of antibiotics in poultry breeding has led to drug resistance pathogenic microorganisms. With long-term dependence on antibiotics, immunity decreased, increased susceptibility and seriously affecting the quality protein products consumer health. Chinese medicinal herbs come mainly from nature are natural products, so called green feed additives. It become an important substitute for high-quality livestock products. In this study, Wanxi White Geese were used as research...
At present, there are many reports about the treatment of cricopharyngeal achalasia by injecting botulinum toxin type A (BTX-A) into muscle guided ultrasound, electromyography or CT in China, but is no report BTX-A endoscope. This study aims to evaluate efficacy endoscopic injection combined with balloon dilatation after brainstem stroke, and provide a better method for dysphagia stroke.
To further improve the department information system, and to establish a multi-parameter critical care medicine database, which can provide data for analysis research of big in medicine, references other medical institutions relevant databases.On premise fully understanding needs clinical scientific research, based on Critical Care Medicine Clinical Information System, First Medical Center Chinese PLA General Hospital integrated patients' case hospital system (HIS), electronic records (EMR),...
Mechanical thrombectomy (MT) has become an important treatment method for acute anterior circulation large vessel occlusion. The carotid artery approach is a fast and effective alternative when the transfemoral difficult due to vascular variation. present study reports on seven cases of stroke where direct was used obtain access.Patients with occlusion treated via access between January 2018 2020 were retrospectively analyzed. Brain computed tomography (CT) angiographic imaging results,...