A5101712333- Wound Healing and Treatments
- Phytoestrogen effects and research
- Seaweed-derived Bioactive Compounds
- Phytase and its Applications
- Plant Pathogens and Fungal Diseases
- Advancements in Transdermal Drug Delivery
- Fungal Biology and Applications
- Protein Hydrolysis and Bioactive Peptides
- Proteins in Food Systems
- Edible Oils Quality and Analysis
- Plant Physiology and Cultivation Studies
- Electrospun Nanofibers in Biomedical Applications
- Fermentation and Sensory Analysis
- Virus-based gene therapy research
- Hemostasis and retained surgical items
- Meat and Animal Product Quality
- 3D Printing in Biomedical Research
- Pickering emulsions and particle stabilization
- Probiotics and Fermented Foods
- Proteoglycans and glycosaminoglycans research
- Analytical chemistry methods development
- Leaf Properties and Growth Measurement
- Plant Virus Research Studies
- Planarian Biology and Electrostimulation
- Algal biology and biofuel production
Nanjing Agricultural University
2025
HKUST Shenzhen Research Institute
2024
Army Medical University
2022-2024
Southwest Hospital
2022-2024
Sichuan University
2024
University of Hong Kong
2024
Education Department of Heilongjiang Province
2023
Wuhan University of Science and Technology
2017-2023
Maastricht University
2022-2023
Guiyang Medical University
2023
Abstract Wounds infected with multidrug‐resistant (MDR) bacteria are increasingly threatening public health and challenging clinical treatments because of intensive bacterial colonization, excessive inflammatory responses, superabundant oxidative stress. To overcome this malignant burden promote wound healing, a multifunctional cryogel (HA/TA2/KR2) composed hyaluronic acid (HA), tannic (TA), KR‐12 peptides is designed. The exhibited excellent shape‐memory properties, strong absorption...
Polysaccharides from Morchella esculenta have been proven to be functional and helpful for humans. The purpose of this study was investigate the chemical structure anti-proliferating antitumor activities a polysaccharide (MEP) extracted by pulsed electric field (PEF) in submerged fermentation. endo-polysaccharide separated purified column chromatography Gel permeation chromatography, analyzed gas chromatography. MEP with an average molecular weight 81,835 Da consisted xylose, glucose,...
Interstitial skin fluid (ISF) is an emerging alternative source of blood samples that has attracted great interest from researchers. It a very promising way to use microneedle patches for extracting ISF. However, the recovery ISF still faces challenges, such as long extraction time and low volume, which may affect analysis biomarkers. Traditional centrifugation methods cannot completely recover ISF, leads inaccuracy in detection. In this paper, prepared polyvinyl alcohol/polyvinylpyrrolidone...
As the most common form of dementia in humans, Alzheimer's disease (AD) is linked to misfolding and aggregation amyloid-β (Aβ) peptides. Gold nanoparticles (AuNPs) can encapsulate molecules therapeutic value enhance transport drugs through blood-brain barrier (BBB) neurodegenerative diseases. AuNPs also have antioxidant effect, anti-amyloidosis unique optical properties nano-scaled chirality. They been widely investigated diagnosis AD owing their excellent properties. Recent years, focus on...
Most traditional wound dressings only partially meet the needs of healing because their single function. Patients usually suffer from increasing cost treatment and pain resulting frequent changing dressings. Herein, we have developed a mutifunctional cryogel to promote bacterial infected based on biocompatible polysaccharide.The multifunctional is made up compositive scaffold chitosan (CS), gelatin (Gel) tannic acid (TA) in situ formed silver nanoparticles (Ag NPs). A liver bleeding rat...
Abstract Although near‐infrared (NIR) light‐based photothermal therapies have shown therapeutic potential for infected wounds, the attenuation of NIR light intensity in tissue has severely limited usage deep bacterial infections. Herein, magneto‐thermal responsive bilayer microneedles (Fe‐Se‐HA MNs) consisting functionalized hyaluronic acid (HA), ferro‐ferric oxide (Fe 3 O 4 ), and micelle‐protected selenium nanoparticles (SeNPs@LAS) are constructed to overcome this challenge based on a...
Objective: Resveratrol has been confirmed to improve bone quality and delay osteoporosis, but the mechanisms have not thoroughly elucidated. In this report, we investigated osteogenic differentiation effect of resveratrol on senescent mesenchymal stem cells (BMSCs) involvement AMP-activated protein kinase (AMPK)/ reactive oxygen species (ROS) signaling pathway.Methods: Cell senescence, viability, BMSCs influenced by were ROS production AMPK expression detected.Results: characterized...
Abstract Scar formation seriously affects the repair of damaged skin especially in adults and excessive inflammation has been considered as reason. The self-assembled peptide-hydrogels are ideal biomaterials for wound healing due to their similar nanostructure natural extracellular matrix, hydration environment serving drug delivery systems. In our study, resveratrol, a polyphenol compound with anti-inflammatory effect, is loaded into peptide-hydrogel (Fmoc-FFGGRGD) form dressing (Pep/RES)....
Abstract The traditional way of disease diagnosis is to detect biomarkers in serum, blood, urine, and saliva, but it often faces wound infection pain, usually requires professional medical personnel operate, which unacceptable for most people. As a result, minimally invasive detection has attracted wide attention expected become new method patient monitoring diagnosis. Interstitial fluid (ISF) acts as medium between cells the circulatory system, serving reservoir biomolecules, nutrients,...
Soybean sprouts are a very popular vegetable in Southeast Asian countries and regions. Zinc-rich soybean can help to improve Zn deficiency humans. The aim of this study was prepare Zn-enriched through agronomic biofortification (germination with ZnSO4 solution) order provide consumers dietary material for supplementation.A suitable concentration solution used cultivation found be less than or equal 20 µg mL(-1) . Upon 10 solutions, content (102 163 vs 32 mg kg(-1) dry weight (DW)),...
Abstract The loosening of implants is an important clinical issue, particularly for patients with osteoporosis. In these patients, implant should preferably both promote osteoblast differentiation and repress osteoclastic resorption. the present study, we fabricated coatings containing TiO 2 nanotubes (NTs) incorporated strontium (Sr) on titanium (Ti) surfaces through hydrothermal treatment. amount loaded Sr was controlled by hydrothermally treating samples in a Sr(OH) solution 1 3 h...
Abstract Volatiles of cherry wines were extracted by headspace solid phase microextraction (HS‐SPME) and analyzed gas chromatography mass spectrometry (GC‐MS), multivariate statistical techniques (such as principal component analysis (PCA) cluster (CA) correlation analysis) to differentiate sensory attributes 3 groups the through characterization volatiles wine. Seventy‐five identified in 9 samples, including 29 esters, 22 alcohols, 8 acids, ketones, 5 aldehydes, miscellaneous compounds. The...
Morchella conica Pers. (M. conica) has been used both as a medical and edible mushroom possesses antimicrobial properties antioxidant activities. However, the of polysaccharides purified from M. have not studied. The aim this study was to investigate in vitro polysaccharide NMCP-2 (neutral polysaccharides-2) conica, determined by radical scavenging assay H2O2-induced oxidative stress HEK 293T cells. Results showed that with an average molecular weight 48.3 kDa possessed much stronger...
Phosphatidylethanolamine (PE) and phosphatidylserine (PS) have been shown to increase the antioxidant activity of α-tocopherol. This study investigated ability PE or PS different tocopherol homologues in bulk oil. In addition, a phospholipase-D-modified lecithin (high PE) α-tocopherol was determined. Results showed that much more effective than at increasing homologues. The combination mixed tocopherols with presented greatest activity, hydroperoxides hexanal lag phases 54 53 days compared...
Ultrasonic-microwave synergistic extraction (UMSE) was used to extract from Morchella conica polysaccharide (MCP). The effect of three independent variables (microwave power, ratio water volume raw material weight (W/M ratio), time) on yield optimized using response surface methodology with a Box–Behnken design. high R2 values (>.966) demonstrated the and predicted by polynomial model were fitted. optimal conditions for MCP microwave power 210.61 W, W/M 41.07:1, time 126.98 s. Under these...
Microfluidic chip is a promising platform for studying virus behaviors at the cell level. However, only few chip-based studies on infection have been reported. Here, three-layer microfluidic with low shear stress was designed to monitor process of recombinant Pseudorabies (GFP-PrV) in real time and situ, which could express green fluorescent protein during genome replication. The proliferation characteristics GFP-PrV were measured by monitoring fluorescence intensity GFP determining one-step...
An experimental modal test system was established to extract the natural frequencies of "Golden Delicious" apple, after which elasticity index calculated predict apple quality parameters based on orthogonal polynomials method. The in every vibration mode changed dramatically (P = 0.01) along time revolution. multivariate regression methods were used model predictive relationship between and parameters. models juice pH support vector presented adequate determination coefficients calibration...