- Lung Cancer Diagnosis and Treatment
- Radiology practices and education
- Cardiac Structural Anomalies and Repair
- COVID-19 diagnosis using AI
- Ultrasound in Clinical Applications
- Pulmonary Hypertension Research and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging and Pathology Studies
- Cardiac Imaging and Diagnostics
- Diversity and Career in Medicine
- Kawasaki Disease and Coronary Complications
- Advanced X-ray and CT Imaging
- COVID-19 Clinical Research Studies
- Coronary Artery Anomalies
- Tracheal and airway disorders
- Trauma Management and Diagnosis
- Radiation Dose and Imaging
- Airway Management and Intubation Techniques
- Proteoglycans and glycosaminoglycans research
- Medical Imaging Techniques and Applications
- COVID-19 and healthcare impacts
- Cardiac Arrhythmias and Treatments
- Ectopic Pregnancy Diagnosis and Management
- Congenital Heart Disease Studies
- Cell Adhesion Molecules Research
University of Maryland, Baltimore
2017-2024
University of Maryland Medical Center
2019-2024
Hadassah Medical Center
2021
IPS Research (United States)
2021
Philips (United States)
2021
Mount Sinai Hospital
2020
Staten Island University Hospital
2020
Montefiore Medical Center
2020
Massachusetts General Hospital
2017-2018
Mount Sinai Beth Israel
2015-2016
Heparan sulfate proteoglycans are essential for biological processes regulated by fibroblast growth factors (FGFs). (HS) regulates the activity of FGFs acting as a coreceptor at cell surface, enhancing FGF-FGFR affinity, and being storage reservoir in extracellular matrix (ECM). Here we demonstrate critical role heparanase during mouse submandibular gland (SMG) branching morphogenesis. Heparanase, an endoglycosidase, colocalized with perlecan basement membrane epithelial clefts SMGs....
To evaluate the sensitivity, specificity, and severity of chest x-rays (CXR) CTs over time in confirmed COVID-19+ COVID-19- patients to determinants false negatives.In a retrospective multi-institutional study, 254 RT-PCR verified with at least one CXR or CT were compared age- gender-matched controls. severity, specificity determined respect after onset symptoms; sensitivity for without stratification. Performance serial CXRs against was by comparing area under receiver operating...
Background The American College of Radiology updated Lung Imaging Reporting and Data System (Lung-RADS) version 1.0 to 1.1 in May 2019, with the two key changes involving perifissural nodules (PFNs) ground-glass (GGNs) now designated as a negative screening result. This study examines effects these using National Screening Trial (NLST) data. Purpose To determine frequency PFNs GGNs reclassified from category 3 or 4A more benign 2 Lung-RADS 1.1, compared 1.0, CT scans NLST. Materials Methods...
Background Atypical manifestations of coronavirus disease 2019 (COVID-19) are being encountered as the pandemic unfolds, leading to non-chest CT scans that may uncover unsuspected pulmonary disease. Purpose To investigate patients with primary nonrespiratory symptoms who underwent abdomen or pelvis cervical spine neck findings highly suspicious for COVID-19. Materials and Methods This retrospective study from March 10, 2020, April 6, involved three institutions, two in a region considered...
BACKGROUND. A possible association has been reported between COVID-19 messenger RNA (mRNA) vaccination and myocarditis. OBJECTIVE. The purpose of our study was to describe cardiac MRI findings in patients with myocarditis after mRNA vaccination. METHODS. This retrospective included without known prior SARS-CoV-2 infection who underwent May 14, 2021, June for suspected within 2 weeks Information regarding clinical presentation, hospital course, events discharge were recorded. cardiothoracic...
Abstract Recently, we reported that the laminin α5 synthetic peptide A5G27 (RLVSYNGIIFFLK, residues 2,892-2,904) binds to CD44 receptor of B16-F10 melanoma cells via glycosaminoglycans on and inhibits tumor cell migration, invasion, angiogenesis in a dominant-negative manner. Here, have identified potential mechanism activity using WiDr human colorectal carcinoma cells. bound heparin-like chondroitin sulfate B glycosaminoglycan side chains CD44. Cell binding fibroblast growth factor (FGF2)...
Myocardial calcifications can arise following damage to myocardial tissue or in the setting of disturbances calcium and phosphorus balance. They are associated with a number cardiac sequelae, as well higher mortality. Three cases rapid-onset that developed within course 5 13 weeks patients who had history sepsis renal failure while undergoing hemodialysis described. Baseline imaging from several prior without calcification shown for each three patients, demonstrating rapid onset these...
Neutral lipid storage disease with myopathy is a rare genetic syndrome of abnormal intracellular lipolysis leading to droplet accumulation in skeletal and cardiac muscle. Because variability clinical presentations, multidisciplinary approach essential for diagnosis treatment.
Preprocedure CT Findings of Right Heart Failure as a Predictor Mortality After Transcatheter Aortic Valve ReplacementRydhwana Hossain, MD1, Lydia Chelala, Ghassan Sleilaty, MD2, Sagar Amin, Jenanan Vairavamurthy, MD3, Rong Chen, PhD1, Anuj Gupta, MD4, Jean Jeudy, MD1 and Charles White, MD1Audio Available | Share
Purpose The purpose of this study is to bring attention an atypical form metastatic pulmonary calcification, which conventionally described as a metabolic process with upper lobe predominance in patients specific clinical history, has not been reported distinct entity. Methods Patients calcification (MPC) were first identified mPower keyword search, including MPC or calcifications on computed tomography chest radiological reports. then filtered likelihood based off imaging Images reviewed by...
A few case reports of intracavitary coronary arteries (ICCA) have been reported and only a single series on the computed tomography angiography (CCTA) prevalence rate ICCA right artery (RCA). We describe several cases that were noted incidentally also determine overall anomalous ICCA.A retrospective analysis was performed consisting consecutive CCTA as well group from teaching files. To establish rate, we reviewed 464 referred to our center for transcatheter aortic valve replacement. The...
Purpose: To determine the frequency of malignancy nonperifissural juxtapleural nodules (JPNs) measuring 6 to < 10 mm in a subset low-dose chest computed tomographies from National Lung Cancer Screening Trial and rate down-classification such Lung-Reporting Data System (RADS) 2.0 compared with Lung-RADS 1.1. Materials Methods: A secondary analysis was performed. An exemption granted by Institutional Review Board. The dominant noncalcified nodule <10 identified on all available...