- Analytical Chemistry and Sensors
- Fuel Cells and Related Materials
- Advanced battery technologies research
- Liver Disease Diagnosis and Treatment
- Electrocatalysts for Energy Conversion
- Ginseng Biological Effects and Applications
- Pharmacological Effects of Natural Compounds
- Electrochemical sensors and biosensors
- Endoplasmic Reticulum Stress and Disease
- Molecular Sensors and Ion Detection
- Exercise and Physiological Responses
- Neuroinflammation and Neurodegeneration Mechanisms
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Crystallography and molecular interactions
- Conducting polymers and applications
- Lipid metabolism and disorders
- Seaweed-derived Bioactive Compounds
- Fibroblast Growth Factor Research
- Regulation of Appetite and Obesity
- Polymer Surface Interaction Studies
- Porphyrin Metabolism and Disorders
- Signaling Pathways in Disease
- Cancer-related molecular mechanisms research
- Chemokine receptors and signaling
University of Tasmania
2020-2025
Central Hospital of Wuhan
2024
General Hospital of Central Theater Command
2024
Chongqing Medical University
2017-2024
The Affiliated Yongchuan Hospital of Chongqing Medical University
2017-2024
Southern University of Science and Technology
2018-2020
Shanghai University
2017
Institute of Coal Chemistry
2017
National Yang Ming Chiao Tung University
2010-2013
Alkyl chain grafted AEMs have been demonstrated to be highly alkaline stable, anion conductive and fuel cell operable.
Non-alcoholic fatty liver disease (NAFLD) is increasingly prevalent and represents a growing challenge in terms of prevention treatment. The purpose this study to investigate the protective effects ginsenoside Rg1 (Rg1), an active ingredient natural medicine, further clarify its mechanisms, mouse model NAFLD induced by high-fat diet. significantly reduced weight, serum alanine aminotransferase (ALT), aspartate (AST), triglyceride (TG), free acids (FFAs) malondialdehyde (MDA) levels,...
The fabrication art of the membrane electrode assembly (MEA) in a proton-exchange (PEM) fuel cell strongly correlates to performance. It has been recognized that defects, for example, high interfacial resistance between catalyst layers (CLs) and or cracks CLs, may occur during MEA manufacturing process. These defects could greatly influence electrochemical performance cell. To eliminate those improve performance, this study, novel approach PEM cells is developed. With method, Nafion ionomer,...
Nonalcoholic fatty liver disease (NAFLD) is one of the common diseases in world, and it can progress from simple lipid accumulation to sustained inflammation. The present study was designed investigate effects underlying mechanisms ginsenoside Rg1 (G-Rg1) treatment on NAFLD vitro . HepG2 cells were treated with palmitic acid (PA) induce steatosis inflammation then successively incubated G-Rg1. Lipids analyzed by Oil Red O staining intracellular triglyceride (TG) quantification. Inflammatory...
Undaria pinnatifida fucoidan (UPF), a bioactive sulphated polysaccharide, is widely recognised for its anti-inflammatory, antioxidant, antitumor, anticoagulant, antiviral, and immunomodulatory properties. However, the precise mechanisms by which UPF regulates inflammation neuronal health remain unclear. This study aimed to investigate effects of supplementation on pro-inflammatory cytokines in skeletal muscle, small intestine, hypothalamus, as well plasma cytokine levels. Additionally, brain...
Undaria pinnatifida fucoidan (UPF), a bioactive sulphated polysaccharide, is widely recognised for its anti-inflammatory, antioxidant, antitumor, anticoagulant, antiviral, and immunomodulatory properties. However, the precise mechanisms by which UPF regulates inflammation neuronal health remain unclear. This study aimed to investigate effects of supplementation on pro-inflammatory cytokines in skeletal muscle, small intestine, hypothalamus, as well plasma cytokine levels. Additionally, brain...
Ginsenoside Rg1 (G‑Rg1) is an active ingredient of Panax ginseng, which has previously been reported to attenuate alcohol‑induced hepatic damage; however, the underlying mechanisms remain largely unknown. The present study aimed investigate protective effects G‑Rg1 on cell injury in vitro and a rat model alcoholic hepatitis vivo. For model, L‑O2 cells were incubated with ethanol presence or absence G‑Rg1. vivo rats administered by intragastric injection treated G‑Rg1, dexamethasone as...
Background Allergic disease can be characterized as manifestations of an exaggerated inflammatory response to environmental allergens triggers. Mite allergen Der-p2 is one the major house dust mite, which contributes TLR4 expression and function in B cells allergic patients. However, precise mechanisms on remain obscure. Methodology/Principal Findings We investigated effects proinflammatory cytokines responses Toll-like receptor-4 (TLR4)-related signaling human activation. demonstrated that...
In response to aggravation by activated microglia, IL-13 can significantly enhance ER stress induction, apoptosis, and death via reciprocal signaling through CCAAT/enhancer-binding protein alpha (C/EBP-α) C/EBP-beta (C/EBP-β). This promotes neuronal survival. Since the induction of cyclooxygenase-2 (COX-2) peroxisome proliferator-activated receptor gamma/heme oxygenase 1 (PPAR-γ/HO-1) plays a crucial role in promotion protection from respectively; here, we investigated regulating C/EBPs...
Fucoidans, known for their diverse biological properties such as anti-inflammatory, antiviral, antitumor, and immune-stimulatory effects, have recently gained attention potential benefits in exercise endurance, muscle mass, anti-fatigue. However, the mechanisms by which fucoidans enhance performance are still unclear. To investigate these we administered 400 mg/kg/day of fucoidan extract derived from Undaria pinnatifida to sixty-four C57BL/6J mice over ten weeks. We evaluated changes running...
Asperuloside is an iridoid glycoside found in many medicinal plants that has produced promising anti-obesity results animal models. In previous studies, three months of asperuloside administration reduced food intake, body weight, and adipose masses rats consuming a high fat diet (HFD). However, the mechanisms by which exerts its properties were not clarified. Here, we investigated homeostatic nutrient-sensing regulating intake mice HFD. We confirmed and, importantly, identified some could...
Highly conductive and water-retentive vinylphosphonic acid-modified aminosilicon oxide cross-linked polymer/perfluorosulfonic acid membranes were prepared.
Three four-arm amphiphilic block copolymers with different chain lengths, consisting of a hydrophilic polyethylene glycol (PEG) and hydrophobic segment polycaprolactam (PCL), were synthesized used to encapsulate the high-efficient oxygen probe platinum(II)-5,10,15,20-tetrakis-(2,3,4,5,6-pentafluorophenyl)-porphyrin (PtTFPP) form polymer micelles. This approach enabled use PtTFPP in aqueous solution for biosensing. Experimental results demonstrated that particle sizes these nano-oxygen...
Obesity produces a systemic low-grade inflammation associated with many adverse health conditions and, as we recently learned, complications of COVID-19. Functional studies in animal models have demonstrated that asperuloside, an iridoid glycoside found medicinal plants, has produced promising anti-obesity results. However, the safety profile and anti-inflammatory properties asperuloside remain unknown. Here, confirmed previously reported importantly, performed toxicity assessing cell...