A5101525982- Circular RNAs in diseases
- MicroRNA in disease regulation
- Parasites and Host Interactions
- Cancer-related molecular mechanisms research
- Soil Carbon and Nitrogen Dynamics
- Macrophage Migration Inhibitory Factor
- Agriculture, Plant Science, Crop Management
- Nanoplatforms for cancer theranostics
- Agriculture and Biological Studies
- Cardiac Fibrosis and Remodeling
- Nanoparticle-Based Drug Delivery
- Parasite Biology and Host Interactions
- Extracellular vesicles in disease
- Adipose Tissue and Metabolism
- Legume Nitrogen Fixing Symbiosis
- Microbial Community Ecology and Physiology
- Radiation Therapy and Dosimetry
- Agricultural Productivity and Crop Improvement
- Cancer-related gene regulation
- Muscle Physiology and Disorders
- Liver Disease Diagnosis and Treatment
- Trace Elements in Health
- Liver Disease and Transplantation
Sichuan Agricultural University
2013-2022
Yangtze University
2019-2021
First Affiliated Hospital of Guangdong Pharmaceutical University
2021
Chengdu University
2020
Genistein may regulate lipid metabolism in adipose tissue of obese mice by regulating the expression miR-222 and its target genes, BTG2 adipor1.
Cardiomyocyte hypertrophy, a prevalent clinical condition is deeply associated with many physiological factors. The underlying mechanisms of cardiomyocyte hypertrophy are not yet fully understood. In this study, H9C2 cells were treated genistein, miR-451 mimic, inhibitor and isoproterenol for 24 h, to study the effect genistein on isoproterenol-induced myocardial in vitro. Simultaneously, ICR mice 21 days evaluate effects phytochemical vivo. Results showed that induced cardiac down-regulated...
Effective, targeted therapy for chronic liver disease nonalcoholic steatohepatitis (NASH) is imminent. MicroRNAs (miRNAs) are a potential therapeutic target, and natural products that regulate miRNA expression may be safe effective treatment strategy disease. Here, we investigated the functional role of miR-451 effects genistein in NASH mouse model. MiR-451 was downregulated various types inflammation, subsequent experiments showed regulates inflammation via IL1β. Genistein phytoestrogen...
Skeletal muscle is the most abundant and a highly plastic tissue of mammals, especially when it comes to regenerate after trauma, but there limited information about mechanism repair its regeneration. In present study, we found that miR-204 downregulated skeletal injury. vitro experiments showed over-expression by transfecting with mimics suppressed C2C12 cell proliferation, migration, blocked subsequent differentiation, whereas inhibition inhibitor converse effects. Furthermore, through...
Circular RNA (circRNA) is a type of closed circular molecules formed by reverse splicing, which exists widely in organisms and has become research hotspot non-coding RNAs recent years. Skeletal muscle plays the role coordinating movement maintaining normal metabolism endocrine organisms. With development sequencing bioinformatics analysis technology, functions regulation mechanisms circRNAs skeletal have been gradually revealed. In this review, we summarize types molecular regulatory...
Straw mulching and N fertilization are effective in augmenting crop yields. Since their combined effects on wheat rhizosphere bacterial communities remain largely unknown, our aim was to assess how the respond these agricultural measures. We studied microbiomes a split-plot design experiment with maize straw (0 8,000 kg ha
连续两 年度, 以紧凑型品种川农 27 和半紧凑型品种绵麦 367 为材料, 在带宽 2 m 和 150×10 4 hm -2 固定密度下, 以传统"双三 零"模式(带宽 m, 20 cm 等行距 5 行)为对照, 设置每带 3 行和行距 30 + (F3-1)、每带 35 (F3-2)、每带 40 (F3-3)、每带 (F4-1)、每带 (F4-2)以及每带 (F4-3)等 6 种配置方式, 研究其对田间通风 透光和群体及个体质量的影响。结果表明, 种植行数由 行减少到 或 行, 同时增大行距后, 孕穗期倒三叶位及基 部透光率显著提高, 群体内部空气流通加强。 通风透光条件的改善显著提升了内行群体及个体质量, 但对边行的影响 较小, 边行优势大幅削减, 内行表现为成穗率提高, 有效穗增多, 孕穗到乳熟期叶面积消减速率减缓, 干物质积累量 增多, 穗粒数、单穗重及产量提高。F3-3 F4-3 处理的产量超过对照, 是该地区带状机条播小麦行数与行距的最佳 配置方式; F3-2 F4-2 处理的产量与对照相当, 但内行个体质量指标优于对照, 也可替代传统"双三零"模式。
Abstract Background: This study aimed to explore the role of lncRNA DLGAP1-AS2 in ovarian cancer (OC). Methods: Expression DLGAP1-AS2, mature miR-16 and precursor paired OC tissues non-tumor collected from 62 patients was determined by RT-qPCR. Correlations were analyzed Pearson’s correlation coefficient. Overexpression achieved cell line UWB1.289 effects overexpression on expression Transwell assays performed analyze regulating invasion migration cells. Results: upregulated inversely...