Background/Objectives: Isolated cecum necrosis (ICN) is a rare disease and there are few reports on it in the literature. We retrospectively analyzed patients with acute abdomen who had ICN, terms of etiology, demographic findings, surgery, prognosis to determine best treatment approach. Methods: Seven per-operative diagnosis isolated cecal were included study. Age, gender, comorbidities, symptoms, laboratory data, imaging modalities, time from symptoms surgical procedure, hospital stay,...

Tumor markers have shown little benefit as a method for screening. However, they can be used clinically the monitoring of tumor recurrence and prognostic factors because higher levels been observed in advanced disease. This study aimed to investigate relationship between preoperative marker different clinical aspects gastric cancer.One hundred six consecutive patients with confirmed diagnosis cancer 106 subjects (age sex matched) no malignancy control group were included prospectively this 3...

This study was designed to evaluate the protective effect of cysteinyl leukotriene receptor antagonist montelukast against pancreatic injury during acute pancreatitis.Acute pancreatitis induced in rats by 20-μg/kg (intraperitoneal) cerulein given at 1-hour intervals within 4 hours. Montelukast administered intraperitoneally a dose 10 mg/kg 15 minutes before first injection. Six hours after or saline injections, animals were killed decapitation. Blood samples collected analyze amylase,...

This study aimed to investigate the effects of melatonin on healing colon anastomosis following chemotherapy.32 rats were randomised into four groups: (a) control group, which underwent sigmoid transection and primary anastomosis; (b) received daily (c) 5-fluorouracil (5-FU) 5-FU for five days prior (d) 5-FU+melatonin anastomosis. The sacrificed Postoperative Day 7 anastomotic bursting pressures measured. segment was extracted hydroxyproline, luminol lucigenin measurement histopathological...

Background: Acute appendicitis is a very common surgical emergency. Early and correct diagnosis early intervention are necessary to prevent complications. It often diagnosed on clinical signs certain ratio of negative appendectomy acceptable. For accurate diagnosis, various scoring systems such as Alvarado, Ohmann, Eskelinen more recently Raja Isteri Pengiran Anak Saleha Appendicitis (RIPASA) have been developed. Objective: In this study, we aimed compare the effectiveness accuracy systems....

PURPOSE: To investigate the effect of medical ozone treatment on experimental acute distal colitis in rats. METHODS: Eighteen rats were randomly distributed into three equal groups; control, (ADC) without and with treatment. Rats control group taken saline. ADC was performed by rectal way 4% acetic acid groups 2 3, 3 treated for weeks both rectally intraperitoneally. At twenty second day colons samples obtained malondialdehyde myeloperoxidase, blood to measure levels TNF-α IL-1β levels....

An increased number of tumor infiltrative lymphocytes (TILs) is considered a favorable prognostic factor in various cancers because it marker antitumoral activity the immune system. In this prospective, non-randomized clinical trial, we evaluated impact preoperative immunonutrition on and neoangiogenesis cancerous tissue patients with locoregional resectable gastric adenocarcinoma.Patients adenocarcinoma were divided non-randomly into two study groups. The first (control) group included who...

Fournier's Gangrene (FG) is the necrotizing fasciitis of perineal region.To compare effectiveness debridement alone and with vacuum-assisted closure in treatment gangrene.Twenty-two patients operated for FG were analyzed retrospectively. Debridement-only + VAC groups compared terms age, gender, predisposing factors, comorbid diseases, intensive care unit hospital stay durations, laboratory results, septic shock, methods, Fournier' gangrene severity index (FGSI) mortality.The M/F ratio was...

Objective: Sigmoid volvulus is most commonly seen in patients between 60 and 80 years old. The management of depends on its location clinical presentation. fundamental aspects treatment include evaluating the viability colon, relieving obstruction, preventing possibility recurrence. We aimed to present clinicopathological characteristics geriatric colonic treated a single center. Methods: Patients diagnosed with this hospital were included study. Mortality rates who underwent did not undergo...

To investigate the effects of medical ozone theraphy on colon anastomosis peritonitis model in rats.Eighteen rats were randomly assigned into three equal groups; control, cecal punctuation and theraphy. Sepsis was performed with a groups 2 3. The administered intraperitonealy for weeks group 3 while other received saline injection. At twenty second day serum obtained TNF-α IL-1β, colonic burst pressures measured tissue samples MDA MPO levels. Histolopatological examination evaluated H&E...

Background: The aim of this study was to assess the possible protective effect proanthocyanidin against cerulein-induced acute pancreatic inflammation (AP) and oxidative injury. Methods: Sprague-Dawley rats were pretreated with proanthocyanidine (100 mg/kg, orally) or saline 15 min before cerulein given by 20 µg/kg subcutaneously at 1-h intervals within 4 hours. Six hours after injections, animals killed decapitation. Blood samples collected analyze amylase, lipase, proinflammatory cytokines...

PURPOSE: To determine the effect of grape-seed extract against ischemia/reperfusion injury in cholestatic liver. METHODS: Eighteen Wistar albino rats were divided into three groups. In control and study groups, cholestasis was provided by bile duct ligation. Seven days later, subjected to 30 min hepatic ischemia, followed 60 reperfusion. Oral administration 50 mg/kg/day started 15 before ligation continued second operation group. Serum, plasma liver samples taken. Laboratory analysis, tissue...

Extragastrointestinal stromal tumors that arise in the pancreas are extremely rare and managing them can be difficult, particularly if located head of pancreas. This case report aims to contribute existing data literature regarding extragastrointestinal with unusual locations. We present a 56-year-old man who presented recurrent mild right upper quadrant abdominal pain. Abdominal computed tomography magnetic resonance imaging revealed mass lesion diameter 10 cm localized...

Despite adequate treatment with proton pump inhibitors (PPIs), symptoms of gastroesophageal reflux disease (GERD) may remain persistent as well Barrett's esophagus emerge. It be proposed that the relaxant effect PPIs on smooth muscles lead to resistance symptoms. The aim this study is investigate effects rabeprazole lower esophageal sphincter (LES) pressure a rat model.Sixteen rats were grouped control and groups. After obtaining LES tissues followed by 60 min equilibration period for...

The aim of this study to investigate the effect an immunonutritional (IN) oral formula enriched with arginine, omega-3 fatty acids and nucleotides in methotrexate (MTX)-induced experimental intestinal mucositis model. In study, 32 rats were divided into four groups consisting eight animals each. Control group fed for 5 days only saline gavage, IN three times a day, MTX intraperitoneal single dose (20 mg/kg), followed by MTX-IN MTX, day. blood jejunal tissue sample collected then sacrificed...

This study aimed to investigate the additional effects of perioperative immunonutrition (IMN) compared with preoperative on anthropometric, nutritional, and biochemical parameters, hospital stay postoperative complications in patients colorectal cancer. Oral supplementation enriched arginine, omega-3 fatty acids, dietary nucleotides was given 25 before after operation (Group 2); received same formula surgery standard isocaloric nutrition following 1). Postoperative body weight, mass index...

Hoarseness due to recurrent laryngeal nerve (RLN) injury is the most feared complication of thyroid surgery. Scars and anatomical changes caused by previous surgeries make finding RLN during redo difficult. We aimed analyze results inferior-to-superior dissection technique that we applied find in surgeries.

It has been reported that proton pump inhibitors induce relaxation in different types of smooth muscles. The aim this study is to investigate vitro effects on human pylorus muscle.Pyloric sphincters were studied 10 patients who operated for stomach cancer. In isolated organ bath, control and re-sponse rabeprazole recorded following contraction with carbachol. During the treatment experiment, while distilled wa-ter was applied during experiment every 5 minutes, administered minutes at doses...

Epidural anesthesia is usually preferred as an adjunct to general in patients undergoing intra-abdominal operations. However, preferring epidural solely selected with poor geneal health, severe cardiopulmonary disease or high risk may protect the against possible adverse effects of anesthesia. This type should be performed carefully by experienced anesthetists since it cause effects, including death. In this case report, we would like share technical aspects and follow-up old patient...

We aimed to compare three endoscopy operators who performed colonoscopy in different styles terms of procedure results, quality, and operator comfort during the procedure.A total 246 patients, underwent routine screening for precancerous lesions between May December 2022 Istanbul Haydarpaşa Numune Education Research Hospital, Istanbul, Turkey, were prospectively analyzed. The results (singleoperator sitting, single standing, two standing) compared with each other. following criteria...