A5054799583- Diabetes Treatment and Management
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes Management and Research
- Blood Pressure and Hypertension Studies
- Metabolism, Diabetes, and Cancer
- Medication Adherence and Compliance
- Acute Ischemic Stroke Management
- Lipoproteins and Cardiovascular Health
- Cardiovascular Function and Risk Factors
- Cardiovascular Health and Risk Factors
- Chronic Kidney Disease and Diabetes
- Nutrition and Health in Aging
- Chronic Disease Management Strategies
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Liver Disease Diagnosis and Treatment
- Diet and metabolism studies
- Cardiovascular Health and Disease Prevention
- Diabetes and associated disorders
- Diabetes Management and Education
- Dialysis and Renal Disease Management
- Clinical practice guidelines implementation
- Diabetic Foot Ulcer Assessment and Management
- Hepatitis C virus research
- Cardiovascular Disease and Adiposity
- Skin Diseases and Diabetes
Niigata University
2016-2025
Niigata Institute of Technology
2018-2024
Yamamoto Hospital
2022
Nagaoka Red Cross Hospital
2017
Abstract Purpose To evaluate the accuracy of various claims‐based definitions diabetes‐related complications (coronary artery disease [CAD], heart failure, cerebrovascular and dialysis). Methods We evaluated data on 1379 inpatients who received care at Niigata University Medical & Dental Hospital in September 2018. Manual electronic medical chart reviews were conducted for all patients with regard to used as gold standard. Sensitivity, specificity, positive predictive value (PPV)...
Background Machine learning (ML) algorithms have been widely introduced to diabetes research including those for the identification of hypoglycemia. Objective The objective this meta-analysis is assess current ability ML detect hypoglycemia (ie, alert coinciding with its symptoms) or predict before symptoms occurred). Methods Electronic literature searches (from January 1, 1950, September 14, 2020) were conducted using Dialog platform that covers 96 databases peer-reviewed literature....
To determine the impact of metabolic syndrome (MetS) and/or dysfunction-associated fatty liver disease (MAFLD), which are pathophysiologically similar and include insulin resistance, on development new-onset cardiovascular with without type 2 diabetes according to sex.This study included 570,426 individuals a history who were enrolled in nationwide claims database from 2008 2016 classified by presence or absence MetS MAFLD stratified sex. The index was used that required diagnosis MAFLD....
Although conventional interventions for people at high risk of developing type 2 diabetes are usually conducted face-to-face, such burdensome health care providers. We developed a lifestyle intervention program combining coaching via smartphone application augmented by intermittently scanned continuous glucose monitoring without burdening Its effectiveness glycemic control and body weight reduction in was investigated.
OBJECTIVE To determine associations of systolic blood pressure (SBP) and diastolic (DBP) with new-onset coronary artery disease (CAD) or cerebrovascular (CVD) according to glucose status. RESEARCH DESIGN AND METHODS Examined was a nationwide claims database from 2008 2016 on 593,196 individuals. A Cox proportional hazards model identified risks CAD CVD events among five levels SBP DBP. RESULTS During the study period 2,240 3,207 occurred. Compared ≤119 mmHg, which lowest quintile SBP, hazard...
Abstract Purpose To determine the degree of control multiple risk factors under real-world conditions for coronary artery disease (CAD) according to presence or absence diabetes mellitus (DM) and whether reaching multifactorial targets blood pressure (BP), low-density lipoprotein-cholesterol (LDL-C), HbA1c, current smoking is associated with lower risks CAD. Methods We investigated effects on subsequent CAD number controlled among BP, LDL-C, in a prospective cohort study using nationwide...
Abstract Aim To compare the long‐term efficacy of sodium‐glucose co‐transporter‐2 inhibitors and dipeptidyl peptidase‐4 as second‐line drugs after metformin for patients not at high risk atherosclerotic cardiovascular disease (ASCVD). Materials methods In a 52‐week randomized open‐label trial, we compared ipragliflozin sitagliptin in Japanese diagnosed with type 2 diabetes, without prior ASCVD treated metformin. The primary endpoint was glycated haemoglobin (HbA1c) reduction ≥0.5% (5.5...
Abstract Background The prevalence of diabetes is rising, and develops at a younger age in East Asia. Although lower limb amputation negatively affects quality life increases the risk cardiovascular events, little known about rates predictors among persons with from young adults to those “young‐old” category (50–72 y). Methods We analyzed data nationwide claims database Japan accumulated 2008 2016 involving 17,288 people aged 18–72 y (mean 50.2 y, HbA1c 7.2%). Amputation occurrence was...
Abstract Background Although both a history of cerebrovascular disease (CVD) and glucose abnormality are risk factors for CVD, few large studies have examined their association with subsequent CVD in the same cohort. Thus, we compared impact prior status, combinations on using real-world data. Methods This is retrospective cohort study including 363,627 men aged 18–72 years followed ≥ 3 between 2008 2016. Participants were classified as normoglycemia, borderline glycemia, or diabetes defined...
Objective Declining healthy life expectancy due to functional disability is relevant and urgent because of its association with decreased quality also for enormous socioeconomic impact. The aim this study examine the impact diabetes, hypertension, dyslipidemia physical activity habits on among community-dwelling Japanese adults. Research design methods This a population-based retrospective cohort including 9673 people aged 39–98 years in Japan (4420, men). Functional was defined as condition...
Aims: To investigate the combined effects of blood pressure (BP) and glycemic status on risk heart failure. Methods: Examined was a Japanese claims database from 2008 to 2019 589 621 individuals. Cox proportional hazards model identified incidence failure among five levels SBP/DBP according glucose status. Results: Mean follow-up period 5.6 years. The per 1000 person-years in normoglycemia, borderline glycemia, diabetes groups were 0.10, 0.18, 0.80, respectively. In linear trend observed...
Objectives It has been hypothesised that smoking intensity may be related to occupational stress. This study aimed investigate whether stress, including problems with superiors or co-workers, is a driver of smoking. Design Cross-sectional study. Setting and participants 59 355 employees (34 865 men 24 490 women) across multiple occupations who completed self-reported questionnaire-based stress survey between April 2016 March 2017 in Niigata Prefecture. Main outcome measures Stress scores for...
BMI ≥25.0 and WC ≥90 are components of the International Diabetes Federation (IDF) definition metabolic syndrome for Asians. We have investigated more suitable levels risk CAD using large-scale nationwide claims data on people with without DM in same cohort. The sample included 157,220 Japanese men 18-72 years age a known history at baseline (DM: 15,465 patients, non-DM: 141,755 patients). Multivariate Cox regression model examined association BMI/WC categories their combination CAD. During...
To determine associations between severity of hypertension and risk starting dialysis in the presence or absence diabetes mellitus (DM). A nationwide database with claims data on 258 874 people without DM aged 19-72 years Japan was used to elucidate impact dialysis. Initiation determined from using International Classification Diseases-10 codes medical procedures. Using multivariate Cox modeling, we investigated predict initiation DM. Hypertension significantly associated regardless The...
Although both glucose abnormalities and a history of cardiovascular disease such as coronary artery (CAD) or cerebrovascular (CVD) are risk factors for disease, few studies have examined the association changes in tolerance subsequent CAD CVD those with without same cohort. Thus, we studied impact status over 2 years on either. During 2-year baseline period which there was worsening, no change, improvement according to CAD/CVD, 363,856 people were classified having either normoglycemia...
Abstract Aims/Introduction History of coronary artery disease (CAD), cerebrovascular (CeVD), type 2 diabetes and their combined effect on cardiovascular are essential for risk management. We investigated the association prior CAD, CeVD, combination with disease. Materials Methods This is a historical cohort study including 342,033 participants (aged 18–72 years) followed up ≥5 years between 2008 2016. Participants were classified into eight groups (with or without CeVD diabetes). Type...