A5079550262- Algal biology and biofuel production
- Aquatic Ecosystems and Phytoplankton Dynamics
- Microbial Fuel Cells and Bioremediation
- Marine and coastal ecosystems
- Marine Toxins and Detection Methods
- Liver Disease Diagnosis and Treatment
- Biofuel production and bioconversion
- Biodiesel Production and Applications
- Carbon Dioxide Capture Technologies
- Peroxisome Proliferator-Activated Receptors
- Microbial Metabolic Engineering and Bioproduction
- Fermentation and Sensory Analysis
- Hemoglobinopathies and Related Disorders
- Adipose Tissue and Metabolism
- Effects and risks of endocrine disrupting chemicals
- Biocrusts and Microbial Ecology
- Iron Metabolism and Disorders
- Diet and metabolism studies
- Mass Spectrometry Techniques and Applications
- Phase Equilibria and Thermodynamics
- Biological Control of Invasive Species
- Fungal and yeast genetics research
- Advanced Chemical Sensor Technologies
- Erythrocyte Function and Pathophysiology
- Catalysis for Biomass Conversion
Universidade do Estado de Minas Gerais
2023-2025
Universidade de São Paulo
2018-2024
Pfizer (United States)
2020-2024
Weatherford College
2021
Background & AimsDisordered metabolism, steatosis, hepatic inflammation, and fibrosis contribute to the pathogenesis of nonalcoholic steatohepatitis (NASH). Acetyl-CoA carboxylase (ACC) catalyzes first committed step in de novo lipogenesis (DNL) modulates mitochondrial fatty acid oxidation. Increased DNL flux reduced oxidation are hypothesized steatosis. Some proinflammatory cells also show increased dependency on DNL, suggesting that ACC may regulate aspects inflammatory response NASH....
Branched chain amino acid (BCAA) catabolic defects are implicated to be causal determinates of multiple diseases. This work aimed better understand how enhancing BCAA catabolism affected metabolic homeostasis as well the mechanisms underlying these improvements. The rate limiting step is irreversible decarboxylation by branched ketoacid dehydrogenase (BCKDH) enzyme complex, which post-translationally controlled through phosphorylation BCKDH kinase (BDK). study utilized BT2, a small molecule...
Hydrogen is an abundant element and a non-polluting fuel that can be biologically produced by microalgae. The aim of this research was to investigate biological hydrogen production Chlamydomonas reinhardtii (CC425) moewusii (SAG 24.91) direct biophotolysis in batch cultures. Strains were cultivated TAP growth medium (pH 7.2) two phases: the first stage, cultures maintained aerobic condition until middle exponential phase; second biomass transferred closed anaerobic photobioreactors under...
Efficient co-fermentation of glucose and xylose remains a critical hurdle in second-generation bioethanol production. In this study, we evaluated two non-Saccharomyces yeasts—Wickerhamomyces anomalus UEMG-LF-Y2 Diutina rugosa UEMG-LF-Y4—under mixed-sugar conditions. D. exhibited superior metabolism ethanol productivity, achieving maximum volumetric productivity (QP) 0.55 g/L·h medium containing 20 g/L 40 xylose. Its highest yield (YP/S) reached 0.45 g EtOH/g sugar, comparable to results from...
The search for alternative fuel sources to replace non-renewable energy is a highly relevant topic in current research studies. Both biomethane and biohydrogen can be obtained from several anaerobic biological processes, which have some advantages over traditional supply chains, especially due the ability use various wastes and/or wastewaters as feedstock biogas production, considered renewable fuel. These features combined with low inputs support potential of these processes play key role...
The kidney plays an important role in iron homeostasis and mesangial cells (MCs) are phagocytic for glomerular homeostasis. Sickle hemoglobin (HbS) modulators promising clinical candidates treatment of sickle cell disease. Although they prevent disease pathophysiology HbS polymerization red blood (RBC) sickling by increasing oxygen affinity, higher affinity can also cause transient tissue hypoxia with compensatory increases erythropoiesis subsequent RBC turnover. CD-1 mice treated modulator...
Abstract Hydrogen is a renewable fuel that can be biologically produced by green algae in closed anaerobic photobioreactors with light and organic carbon as energy sources. This research aimed to investigate the influence of sulfur concentration intensity on hydrogen ethanol production, well nutrient removal Chlamydomonas reinhardtii (CC425) batch cultures. The strain was cultivated two phases: first step, cultures were maintained under aerobic conditions obtain biomass; second biomass...
In order to investigate the influence of trophic state from a subtropical reservoir in São Paulo, Brazil, competition between species dominant, Raphidiopsis raciborskii and Monoraphidium contortum, an assay was carried out interaction these microorganisms simulating its current conditions, mesotrophic, another supereutrophic condition, as well detect production saxitoxin by cyanobacteria. The experiments were conducted climate-controlled room for 15days triplicate pure mixed cultures each...