A5028910139- Air Quality and Health Impacts
- Health and Wellbeing Research
- Liver Disease Diagnosis and Treatment
- Climate Change and Health Impacts
- Cardiovascular Health and Risk Factors
- Cardiovascular Disease and Adiposity
- Health Promotion and Cardiovascular Prevention
- Health disparities and outcomes
- Nutrition, Health and Food Behavior
- Obesity, Physical Activity, Diet
- Acute Ischemic Stroke Management
- Primary Care and Health Outcomes
- Cardiovascular Health and Disease Prevention
- Nutrition and Health in Aging
- Gastroesophageal reflux and treatments
- Blood Pressure and Hypertension Studies
- Bone health and osteoporosis research
- Genetic Associations and Epidemiology
- Healthcare Policy and Management
- Chronic Disease Management Strategies
- Nutritional Studies and Diet
- Thyroid Disorders and Treatments
- Intracerebral and Subarachnoid Hemorrhage Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Diabetes, Cardiovascular Risks, and Lipoproteins
Seoul National University Hospital
2016-2025
National University College
2019-2025
New Generation University College
2019-2025
Seoul National University
2015-2025
Samsung Medical Center
2019
CHA Bundang Medical Center
2019
Toyooka Hospital
2019
Advanced Institute of Convergence Technology
2016-2018
Boramae Medical Center
2014-2016
Seoul Metropolitan Government
2014-2016
Lactobacillus gasseri BNR17 is a probiotic strain isolated from human breast milk. Animal studies reported that inhibited increases in body weight and adipose tissue weights. The purpose of this study was to evaluate the antiobesity effects humans. In randomized, double-blind, placebo-controlled trial, 90 volunteers aged 20–75 years with mass index (BMI) 25 35 kg/m2 were randomized receive placebo, low-dose BNR (BNR-L, 109 CFU/day), or high-dose (BNR-H, 1010 CFU/day) for 12 weeks. Body...
The importance of adherence to antihypertensive treatments for the prevention cardiovascular disease has not been well elucidated. This study evaluated effect medication on specific mortality (ischemic heart [IHD], cerebral hemorrhage, and infarction). Our used data from a 3% sample cohort that was randomly extracted enrollees Korean National Health Insurance. Study subjects were aged ≥20 years, diagnosed with hypertension, started newly prescribed in 2003 2004. Adherence estimated as...
Screening for hepatocellular carcinoma (HCC) is clinically important given that its early detection has remarkable survival benefits. We investigated the possible role of FIB-4, a recently developed noninvasive marker liver fibrosis based on routine laboratory tests, as clinical indicator predicting future HCC among hepatitis B surface antigen (HBsAg) carriers. Our retrospective cohort study involved 986 Korean HBsAg carriers 40 years age or older who visited Seoul National University...
A pilot randomized trial assessed the feasibility and effectiveness of an intervention combining Smartcare (activity tracker with a smartphone application) financial incentives.A three-arm, open-label controlled design involving traditional education, Smartcare, incentives was involved in this study. The latter group received depending on achievement daily physical activity goals (process incentive) weight loss targets (outcome incentive). Male university students (N = 105) body mass index...
Elevated neutrophil to lymphocyte ratio (NLR) has been reported as a marker for chronic inflammation, associated with poor prognosis in ischemic stroke patients, but there no study that investigated its association risk. This was conducted investigate elevated NLR an independent risk factor incidence. Our retrospective cohort included 24,708 generally healthy subjects aged 30–75 who received self-referred health screening at Seoul National University Hospital. Data on incidence retrieved...
Few studies have evaluated the association between being underweight and having cardiovascular disease in general population. We investigated incidence of stroke, myocardial infarction (MI), all-cause mortality according to detailed categories a large population cohort.We included 4 164 364 individuals who underwent health examination that was conducted as part Korean National Health Insurance Service January 2009 December 2012 followed them up determine MI, until 31 2016. Based on body mass...
Underrepresentation of non-European (EUR) populations hinders growth global precision medicine. Resources such as imputation reference panels that match the study population are necessary to find low-frequency variants with substantial effects. We created a panel consisting 14,393 whole-genome sequences including more than 11,000 Asian individuals. Genome-wide association studies were conducted using and population-specific genotype array 72,298 subjects for eight phenotypes. This yields...
Adherence to antihypertensive medication is a critical factor control blood pressure and prevent complications. However, cognitive impairment can negatively affect adherence. In this study, we investigated the association between function adherence among elderly hypertensive patients using Korean National Health Insurance Service Sample Cohort Data of Elderly Cohort. The study included 20,071 prevalence poor medications was 16.4%. A multivariate logistic regression analysis showed that lower...
Objective Many thyroid cancer patients are exposed to long-term thyroid-stimulating hormone (TSH) suppression, often as lifetime treatment, and consequently at risk for cardiovascular disease. We investigated the incidence of coronary heart disease (CHD) ischemic stroke among compared with matched control subjects. Design Retrospective cohort study. Methods A total 182 419 subjects who received thyroidectomy during 2004-2012 were selected from Korean National Health Insurance data, which...
Little is known about the disparities in underweight prevalence among general population high-income countries. We investigated trends and across sociodemographic groups Korean adults older adults. A series of cross-sectional data on national health checkups for aged ≥20 years were analyzed from 2005 to 2016. Based body mass index (kg/m2), was graded as mild (17.0-18.49), moderate (16.0-16.9), severe (<16.0). Underweight compared subgroups 2015-2016. Trends examined 2005-2006...
Abstract Aims Salivary amylase gene ( AMY 1 ) copy number variations CNV s) correlate directly with salivary activity and serum levels. Previously, individuals high s exhibited low postprandial glucose levels early insulin surge, suggesting that numbers may play a role in lowering the risk of resistance. Methods We verified relationship between homeostatic model assessment–insulin resistance HOMA ‐ IR cohort 1257 Korean men aged 20–65 years who visited two medical centres for regular health...
This study aims to investigate the association between insulin resistance (IR) and silent lacunar infarction (SLI) in healthy adults.We recruited 2326 Korean adults who took health checkups, including a brain magnetic resonance imaging. SLI was defined as an measuring 0.3 1.5 cm diameter that localized territory of perforating branches cerebral arteries, seen The homeostasis model assessment-estimated index used for IR estimation, cutoff value its diagnosis Koreans 2.56.The mean age...
Abstract Background The timed up and go test (TUG) is one of the most widely used tests mobility. We aimed to examine whether TUG associated with cardiovascular (CV) events, CV mortality, all-cause mortality. Methods Subjects in senior cohort database Korean National Health Insurance Service (2002–2013) who completed as part Screening Program for Transitional Ages (NSPTA) during 2007–2008 were identified. An abnormal result was defined a time ≥ 10 s. Cox proportional hazard models assess...
To examine the associations between allergic triad (asthma, rhinitis, atopic dermatitis) and risk of dementia.Participants comprised 6,785,948 adults aged ≥40 years who participated in a national health examination 2009 without any history dementia before baseline. From to 2017, we prospectively investigated physician-diagnosed diseases incident (all-cause, Alzheimer's disease [AD], vascular [VaD]) ascertained using insurance claims data.During 8.1 follow-up, 260,705 cases (195,739 AD,...
The purpose of this study was to investigate the association between long-term air pollution exposure and Low Urinary Tract Symptoms (LUTS) in Korean men. This included 7,979 adult men who underwent health checkups. Each subject's annual average levels were estimated using Community Multiscale Air Quality model. LUTS evaluated International Prostate Symptom Score (IPSS) questionnaire, IPSS values analyzed for their with severity. population had an age 56.1 years, a prevalence at 39.8%. None...