A5007795249- Multiple Sclerosis Research Studies
- Neurological Disorders and Treatments
- Cerebral Palsy and Movement Disorders
- Epilepsy research and treatment
- Metabolism and Genetic Disorders
- Botulinum Toxin and Related Neurological Disorders
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Diet and metabolism studies
- Vitamin C and Antioxidants Research
- Long-Term Effects of COVID-19
- Genetics and Neurodevelopmental Disorders
- Human Health and Disease
- Vitamin D Research Studies
- Coenzyme Q10 studies and effects
- Acute Lymphoblastic Leukemia research
- Antiplatelet Therapy and Cardiovascular Diseases
- Mitochondrial Function and Pathology
- Neuroscience and Neuropharmacology Research
- Hip disorders and treatments
- Neurological Disease Mechanisms and Treatments
- Pain Mechanisms and Treatments
- Fungal Plant Pathogen Control
- Birth, Development, and Health
- Attention Deficit Hyperactivity Disorder
- Lipoproteins and Cardiovascular Health
Peoples' Friendship University of Russia
2020-2025
Institute of Practical Psychology and Psychoanalysis
2016-2024
Research Center of Neurology
2017
El Paso County Public Health
2017
City Clinical Hospital
2017
Pirogov Russian National Research Medical University
2007-2016
Moscow State University of Medicine and Dentistry
2012-2013
Central Clinical Hospital and Polyclinic
2009
Vladivostok State Medical University
2008
This ar ticle presen t s da ta on the epidemiology, pathogenesis, modern classi f ica tion and main clinical mani festat ions of Gauche r disease i n chi ldr e . The c ia o di ff nt l diag osis wi h he diseases a give I has b ee show at y effecti ve method trea ting Gaucher is pathogenetic enzyme replacemen ther apy, which relieves ma es tat io disease, imp ovi g qua pa ie d hou havi p ou ced side ec s. mai error diagnosis managemen ti en s, as well un justif ied prescriptions for treatment...
The Ministry of Health the Russian Federation jointly with professional association and experts in field pediatrics, infectious diseases resuscitation has revised guidelines “Clinical Features Management Disease Caused by New Coronaviral Infection (COVID-19) Children” order to provide child population effective medical care during pandemic new coronaviral infection. practical experience specialists from various countries was considered development this document. Special attention should be...
To evaluate the efficacy and safety of two dosing regimens Mexidol film-coated tablets, 125 mg («RPC «PHARMASOFT» LLC Russia), compared with placebo in children attention deficit hyperactivity disorder (ADHD) aged 6 to 12 years.A multicenter randomized, double-blind, placebo-controlled study 3 parallel groups was conducted 14 clinical centres Russian Federation assess Russia) treatment 6-12 years old different regimens. The involved 333 boys girls a confirmed diagnosis ADHD established...
Article presents data about the role of central nervous system pathology in structure children's disability. Principles and directions complex rehabilitation are discussed. Goals rehabilitation, basis for formation program implementation children with pathology, presented. Information is presented on methods disorders used practical activities.
To assess the safety and clinical neurophysiological efficacy of xeomin in children with spastic equinus equinovarus foot deformity cerebral palsy.Sixty-four patients forms palsy (levels I-IV on GMFCS) were enrolled into this multi-center open-label comparative randomized trial. The administered or botox once, each drug being to 32 patients. Efficacy was evaluated based characteristics (the modified Ashworth scale, goniometry) electromyography data. subjects observed for 3 months (90±7 days)...
Nowdays, cerebral palsy is a leader in the structure of chronic diseases childhood. The earliest start rehabilitation children with palsy, continuity and phasing their implementation, systematic comprehensive, individual approach provide to attain optimal physical, intellectual, psychological and/or social functional levels support it, thereby giving them tools designed change lives expand independence According latest scientific data Russia today more than 40 % newborns have various health...
To evaluate efficacy and safety of biosimilars interferon beta-1b (Infibeta) in patients aged 14 to 17 years.Interferon beta 1b was appointed 9 children adolescents (4 boys 5 girls) between the ages years (mean age onset therapy 16.22±1.09).In course there a significant decrease annualrelapse rate (ARR) 0.33±0.5 (from 0 1, r≤0,0001) regression neurological deficit on EDSS scale up ±1.94±0.68 (1.5 3, p≤0.05). No cases cancellation not recorded due poor tolerability or inefficiency.Although...
Alpers-Huttenlocher syndrome is a rare mitochondrial disease connected with mutations in the DNA replicase, polymerase gamma (POLG). The reduction of activity within enzymes replications level DNA. manifests itself once reaches critical point. We can also observe debut variability and progression even among patients identical genotypes normal children onset up to moment clinical presentations debut. Seizures, liver degeneration progressive development regression are classical triad disease....
<h3></h3> Глобальные стратегии антиноцицептивной защиты организма от операционного стресса подразумевают отказ опиоидной аналгезии, поскольку, помимо традиционных побочных эффектов этих препаратов (угнетение сознания, избыточная седация, тошнота и т.д.), доказана их способность формировать опиоид-индуцированную гипералгезию оказывать иммуносупрессивное действие. Отказаться применения опиоидных анальгетиков у детей или сократить до минимума дозы в периоперационный период позволяет концепция...
The vast majority of therapies are being evaluated and introduced for the treatment adult multiple sclerosis (MS). A role these drugs in management pediatric MS has yet to be defined both Russia whole world. Despite fact that today study new population have included routine practices big pharmaceutical agencies, such as FDA EMA, recommendations patients with based not so much on a long period systematic clinical research, but professional consensus international expert associations,...
Medicinal plants and their secondary metabolites are increasingly used in the treatment of diseases complex therapy. Inflammation is a pathological condition that includes wide range such as rheumatic immune-mediated conditions, diabetes, cardiovascular diseases, etc. Three presented review: Harpgophytum procumbens, Curcuma longa, Bosswellia serrata, whose anti-inflammatory effects have been evaluated clinical experimental research. The use Harpgophytum, turmeric boswellia shows these...
Neuromyelitis optica spectrum disorders (NMOSD) is a general term for immune-mediated diseases of the central nervous system whose phenotype includes affection optic nerve, brainstem encephalitis and myelitis. NMOSD most commonly associated with class G antibodies against aquaporin-4 (aquaporin-4 immunoglobulin G, AQP4-IgG), less glycoprotein myelin oligodendrocytes. There are also seronegative variants NMOSD. The article describes our own experience in treating two boys resistant AQP4-IgG...
Optimal maternal nutrition plays a critical role in ensuring healthy pregnancy and normal fetal development. Maternal fatty acids are essential for the growth development of fetus, newborn future adult. Humans unable to synthesize polyunsaturated (PUFAs) depend on dietary intake PUFAs. Adequate two major omega‑3 PUFAs, eicosapentaenoic acid (EPA) docosahexaenoic (DHA), during and/or lactation is considered fundamental adulthood.
In the last decade, there has been a rapid increase in incidence of both stress-induced mental disorders and metabolic diseases (obesity, diabetes, etc.). These may be based on common pathogenetic mechanisms, including activation hypothalamic-pituitary-adrenal axis, changes cellular homeostasis energy metabolism. Nutrition can have positive negative effects body’s adaptive reserves Our article is devoted to description role micronutrients rarely used optimize diet, such as tyrosine,...
Aging is a progressive degenerative condition accompanied by an increasing loss of physiological integrity and function. inevitable process that includes, among other things, imbalance between antioxidant defenses reactive oxygen species, changes in protein mitochondrial turnover, telomere attrition, cellular senescence, epigenetic stem cell depletion. These conditions are associated with mild to moderate inflammation, which always accompanies the aging age-related diseases. Skin very...
Optimal nutrition requires complete provision of the human needs not only for energy, macro- and micronutrients, but also minor biologically active substances. Some most promising chemoprotectors are glucosinolates their derivatives, such as 3,3’-diindolylmethane (DIM). DIM has ability to inhibit development progression neoplasia by regulating multiple intracellular signaling pathways. Currently, clinical efficacy is being studied in breast prostate cancer, possibility using DIM’s...
There is now enough knowledge to suggest that vitamin D status critical overall health and balance. Vitamin deficiency a widespread problem difficulties with its adequate replenishment remain, because many factors influence the absorption bioavailability of influenced by at once. Age, diet, genetics, environmental factors, lifestyle, gut microbiome, pharmaceutical formulation all play important roles in modulating body. Future research should continue explore these their interactions develop...
There are many different forms of biologically active food additives, each which has its pros and cons that should be taken into account. The form the supplement directly affects how much at what rate components will released in body. Despite fact some ingredients retain their stability a certain form, most nutrients can used for use various without losing biological value. Whether it’s chewable candies, capsules, powders or tablets, there nuances account order to find optimal meet specific...