A5037884174- Musculoskeletal pain and rehabilitation
- Neurological Disorders and Treatments
- Pain Management and Placebo Effect
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Intensive Care Unit Cognitive Disorders
- Myofascial pain diagnosis and treatment
- Long-Term Effects of COVID-19
- Neurological Disease Mechanisms and Treatments
- Healthcare Systems and Public Health
- Pain Management and Opioid Use
- COVID-19 and healthcare impacts
- Human Health and Disease
- Scoliosis diagnosis and treatment
- Bone and Joint Diseases
- Dementia and Cognitive Impairment Research
- Osteoarthritis Treatment and Mechanisms
- Gut microbiota and health
- Cerebral Palsy and Movement Disorders
- Inflammatory mediators and NSAID effects
- Hematological disorders and diagnostics
- Acute Ischemic Stroke Management
- Cholinesterase and Neurodegenerative Diseases
- Dermatological and COVID-19 studies
- Pain Mechanisms and Treatments
- Chronic Obstructive Pulmonary Disease (COPD) Research
Pirogov Russian National Research Medical University
2007-2022
Ministry of Health of the Russian Federation
2019-2021
A novel coronavirus infection SARS-CoV-2 (COVID19) is especially dangerous for elderly and senile patients. Preventive measures people should cover three areas: 1) direct prevention of the viral infection, 2) preservation functional status geriatric syndromes, including use social support measures, 3) control comorbidities. The clinical pattern COVID-19 in older patients may be atypical, while mildness symptoms (no fever, cough, shortness breath) not correspond to severity prognosis....
The present document developed by the Russian Association of Gerontologists and Geriatricians represents Clinical guidelines on chronic pain in older senile patients. were endorsed Scientific Council Ministry Health Federation December 2020.Clinical are focused geriatricians providing medical care outpatient hospital settings, general practitioners, physiotherapists.The sets out syndrom screening diagnosis principles patients, management treatment approaches patients with pain, as well...
Background. Osteoarthritis (OA) in elderly and senile patients is not only common, but also one of the main diseases affecting duration active life, its quality, appearance addictions loss autonomy. Data on relationship between OA geriatric syndromes (GS) our country are extremely scarce. Aim. To estimate prevalence to analyze associations with HS persons aged 65 years. Materials methods. The study included 4308 people (30% men) 107 years, living 11 regions Russia. were divided into 2...
Background . The prevalence of chronic pain syndrome in general population older adults the Russian Federation is unknown. Aim To study and features subjects aged ≥65 years. Materials methods There were examined 4308 (30% males) from 65 to 107 years (mean age 78±8 years), living 11 regions Federation, who divided into 3 groups (65–74 years, 75– 84 ≥85 years). All participants underwent a comprehensive geriatric assessment consisted two stages: 1) questioning based on specially designed...
To analyze the geriatric status of patients with chronic pain.One hundred and sixteen a unit, aged 75.66±7.98 years (110 women, 94.8%), were studied. All underwent general clinical examination complex assessment, on results which syndromes identified. Characteristics pain syndrome (cause, intensity, localization) are described.Chronic is identified in 85 (73.3%) patients. Most often localized large joints (n=44 (51.76%)) back (n=50 (58.8%)). The intensity was higher moderate dependence daily...
Delirium is an acute, life-threatening condition manifested by disturbance in consciousness, attention and cognition, which has a multifactorial genesis, severe consequences commonly seen older senile people inpatient. Clinical experience domestic practice shows that delirium diagnosis patients often missed, its signs may be considered as manifestations of other diseases, while the state perceived only alcohol withdrawal. The article presents clinical protocol developed based on firsthand...
Chronic pain among the elderly aged 60 years and above is one of «big» geriatric syndromes, has great prognostic significance in relation to cognitive, functional physical status. The loss muscle strength, mass (sarcopenia) important components chronic syndromes patients. Pathological findings were demonstrated by own observation 116 patients unit 75,667.98 (110 women, 94.8%). Most had a combination several an average which accounted for 6.6. Among them, there falls - 72 (62.1%), 85 (73.3%),...
The standard for the treatment of dementia in Alzheimer's disease (AD) is use basic medicines affecting cholinergic and glutamatergic systems. aim study was a comparative evaluation combined with an NMDA receptor antagonist akatinol memantine donepezil — acetylcholinesterase inhibitor, compared monotherapy AD patients mild dementia. Material methods . included 35 (average age 78.51 years old ± 6.08) at stage 35% received (alzepil), 65% treatment. observation period 12 months. During this...
Novel coronavirus SARS-CoV-2 infection (COVID-19) is a dangerous disease for older adults. Preventive measures in this population should involve three groups of measures: 1) prevention infection; 2) functional decline and geriatric syndromes, including social support; 3) control chronic comorbidity. Older adults are common to present with atypical COVID-19 symptoms, mildness symptoms (no fever, cough, shortness breath) does not correspond the severity prognosis. Delirium may be first...
Locomotive syndrome is a geriatric that corresponds to the model of autonomy loss and emergence addictions due pathology musculoskeletal system with heavy medical social burden. Combination diseases, including osteoarthritis, osteoporosis, dorsopathy, sarcopenia, neuropathy, together impaired physical functioning are clinical characteristics locomotive syndrome. Only comprehensive programs, pain treatment, risk osteoporetic fractures, prevention falls, correction training, psychotherapeutic...
Cognitive disturbances are very frequent problems of the aged people. The review is dedicated to modern methods nonpharmacologic treatment predemention stage and mild dementia. There data reviews meta-analysis cognitive rehabilitation neurodegenerative post-stroke disturbances. mechanisms brain neuroplasticity phenomenon cerebral reserve discussed. relationship between effectiveness aerobic exercises training analysed influence hyppocamp blood supply on also
Increasing life expectancy of the world’s population is accompanied by increasing number elderly patients with dementia. According to various studies, prevalence pain syndrome in dementia ranges from 35.3% 63.5%. The review represents data on epidemiology, clinical manifestations, methods diagnosis and treatment Medicinal non-pharmacological relief are discussed.
<h3></h3> В обзоре рассматривается взаимосвязь нарушений состава и функционирования кишечной микробиоты с развитием нейродегенеративных заболеваний хронической боли. Обсуждается роль в функционировании кишечно-мозговой оси, нейроиммунных взаимодействиях, приводятся современные данные о кишечном дисбиозе при болезнях Альцгеймера Паркинсона, остеоартрозе, нейропатической боли коронавируснй инфекции, скелетно-мышечной фибромиалгии, синдроме раздраженного кишечника др. Модификация помощью...
COVID‑19 continues demonstrating possible complications after recovery. One of these is avascular osteonecrosis, which can lead to bone destruction and patient disability. Cases the development osteonecrosis associated with coronavirus infection were widely reported during SARS epidemic in 2003. They also appear be common infection. All patients who have recovered from infection, especially received glucocorticoids, are threaten development. We describe a case necrosis healthy young woman...
Treatment of osteoarthritis, as the most common pathology musculoskeletal system, presents certain clinical difficulties in comorbid patients. The frequent combination osteoarthritis (OA) and cardiovascular diseases (CVD), diabetes mellitus type 2 other cardiometabolic pathologies raises questions about safety pain relievers presence chronic kidney disease (CKD). Safe treatment for syndrome implies an informed decision risks / benefits using any analgesic intervention. Particular attention...
Objective : to assess the structure and influence of chronic pain (CP) on functional status patients with geriatric syndromes. Patients methods . The study included 370 who were divided into two groups. Group A 300 (mean age 75.1±8.25 years) CP, group B – 70 subjects comparable (75.1±7.75 without CP. All participants found have polymorbidity: Charlson index was 5.55±1.59 points in 5.56±1.64 (p=0.963). underwent a comprehensive assessment (CGE) determine diagnose Results discussion According...