A5004481405- Congenital heart defects research
- Paraoxonase enzyme and polymorphisms
- Genomic variations and chromosomal abnormalities
- Genetic Associations and Epidemiology
- Lipid metabolism and biosynthesis
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diet, Metabolism, and Disease
- Cholesterol and Lipid Metabolism
- Lipoproteins and Cardiovascular Health
- Genomics and Rare Diseases
- Adipokines, Inflammation, and Metabolic Diseases
- Microbial Metabolites in Food Biotechnology
Universidad Autónoma de Guerrero
2015-2017
Mexican Social Security Institute
2015-2017
Hospital de Especialidades
2017
Centro Medico Nacional Siglo XXI
2017
To investigate the correlation among pro- or anti-inflammatory cytokines and two main gut microbiota phyla in obese children.Anthropometric data were obtained from 890 children under 14 years old to determine degree of obesity. Serum cytokine concentration was measured by ELISA. Relative abundance feces evaluated quantitative RealTime PCR assays.Anthropometric biochemical parameters statistically higher overweigth/ (OW/O) than lean (NW), Increased TNF-α levels found that also have a high...
Metabolic syndrome (MetS) is a combination of metabolic disorders associated with an increased risk for cardiovascular disease (CVD). Studies in women reported associations between polymorphisms ESR1, LPL and CETP genes MetS. Our aim was to evaluate the association variants MetS its components. Four hundred eighty were analyzed, anthropometric features biochemical profiles evaluated, genotyping performed by real-time PCR. We found elevated glucose levels (odds ratio (OR) = 2.9; p 0.013)...
Introduction: Apolipoprotein E (ApoE) 4 isoform has been associated with elevated levels of cholesterol, low-density lipoprotein cholesterol (LDL-C), and triglycerides (TGs), meanwhile several polymorphisms in the LDL receptor ( LDLR) gene have increased total LDL-C. Material Methods: We studied 400 women from Southwest Mexico. Anthropometric features biochemical profile were evaluated, genotyping single nucleotide rs429358 rs7412 APOE rs688 LDLR was determined by TaqMan assays. Results:...
Introduction. Increase in body weight is a gradual process that usually begins childhood and adolescence as result of multiple interactions among environmental genetic factors. This study aimed to analyze the relationship between copy number variants (CNVs) five genes four intergenic regions with obesity Mexican children. Methods. We studied 1423 children aged 6-12 years. Anthropometric measurements blood levels biochemical parameters were obtained. Identification CNVs was performed by...
Variantes genéticas se han relacionado con enfermedades de rasgos complejos y factores riesgo asociados a éstas. El propósito este estudio fue evaluar la asociación entre diversos polimorfismos un solo nucleótido (SNP, por sus siglas en inglés) el síndrome metabólico (SM) índice aterogénico plasma (IAP). Se estudiaron mujeres guerrerenses, quienes les realizaron mediciones somatométricas, biomarcadores sanguíneos identificaron SNP siete genes reacción cadena polimerasa (PCR, tiempo real....