Objectives To evaluate the value of vascular index (VI) on Superb Microvascular Imaging (SMI; Canon Medical Systems Corporation, Tokyo, Japan) in comparison with grayscale ultrasound (US) alone for assessing breast masses. Methods We evaluated a total 70 masses (36 malignant and 34 benign lesions) consecutive patients using US SMI. Two radiologists analyzed combination They also measured VI based The diagnostic performance SMI was compared. compared between masses, optimal cutoff determined....

Background The role of preoperative MRI for predicting surgical outcomes in patients diagnosed with ductal carcinoma situ (DCIS) remains uncertain. Purpose To investigate the associations between and DCIS confirmed by using US-guided core-needle biopsy (CNB) to evaluate clinical-pathologic variables associated a benefit from MRI. Materials Methods Women CNB January 2012 December 2016 were included this retrospective study. Propensity score matching 18 confounding covariates was used create...

Abstract Background The upgrade rate of biopsy-confirmed ductal carcinoma in situ (DCIS) to invasive is up 50% on final pathology. We investigated MRI and clinicopathologic predictors the components DCIS diagnosed by preoperative biopsy then compared features between patients with DCIS, microinvasive (mIDC), (IDC) Methods Two hundred one 206 lesions were enrolled. used predict either mIDC or IDC via a cumulative logistic regression analysis. For detected MRI, morphologic kinetic analyses...

Our study investigated whether any sonographic findings could be useful for differentiating between small triple-negative breast cancer (TNBC) and fibroadenoma.This retrospective was approved by our Institutional Review Board, which waived the requirement patient consent. From January 2009 to December 2010, features of 181 pathologically proven TNBC tumors 172 fibroadenomas measuring less than or equal 2 cm in longest dimension were reviewed analyzed according fifth edition Breast Imaging...

Background Invasive micropapillary carcinoma (IMPC) is a rare subtype of breast cancer and presumed to have poorer survival outcome than invasive ductal (IDC). However, studies for clinical outcomes including imaging features are still scarce. Purpose To investigate differences in between IMPC IDC determine prognostic factors indicating survival, features. Material Methods This retrospective study was approved by the institutional review board. Between 2007 2012, 308 women diagnosed with...

Abstract We quantitatively evaluated breast tumor movement and volume changes between magnetic resonance imaging (MRI) scans in prone supine positions. Twenty-seven patients who received neoadjuvant systemic therapy (NST) for breast-conserving surgery were studied. Before after NST, MRI positions performed immediately. Tumor segmentation, volume, position of tumors both Average volumes did not significantly differ ( p = 0.877). from to the origin bottom center sternum was strongly correlated...

The purpose of this study was to perform a comprehensive analysis the radiological and clinicopathological factors that could predict recurrence invasive breast cancer who underwent curative surgery without neoadjuvant chemotherapy. Three hundred sixty-four consecutive women preoperative mammography, ultrasound, magnetic resonance imaging for newly diagnosed cancers between January December 2010 were included. We analyzed findings each modality reviewed histopathological features. A Cox...

Background High levels of tumor-infiltrating lymphocytes (TILs) are associated with improved prognosis and response to therapy in patients human epidermal growth factor receptor 2 (HER2)-positive breast cancer. Purpose This study investigated the associations between TIL magnetic resonance imaging (MRI) findings estrogen (ER)-negative HER-2 positive Material Methods included 110 consecutive surgically confirmed ER-negative HER2-positive cancers who underwent preoperative MRI from January...

Background Accurate determination of human epidermal growth factor receptor 2 (HER2) is important for choosing optimal HER2 targeting treatment strategies. HER2‐low currently considered HER2‐negative, but patients may be eligible to receive new anti‐HER2 drug conjugates. Purpose To use breast MRI BI‐RADS features classifying three levels, first distinguish HER2‐zero from HER2‐low/positive (Task‐1), and then HER2‐positive (Task‐2). Study Type Retrospective. Population 621 invasive ductal...

To investigate the chest computed tomography (CT) and F-18 fluoro-2-deoxy-D-glucose positron emission tomographic (FDG-PET) findings of posttransplant lymphoproliferative disorder (PTLD) in thorax. From November 2004 to February 2013, cases 12 adult patients (3 female 9 male, age range 34–68, median 46 years) with proven PTLD were retrospectively reviewed. The transplanted organs included kidney (5/12), liver (4/12), heart (1/12), combined pancreas hematopoietic stem cell (1/12). We...

This study aims to assess the efficacy and safety of geonchildan, a Korean traditional herbal medicine, for patients with active rheumatoid arthritis (RA) evaluate feasibility large-scale confirmatory clinical trial. is randomized, double-blind, placebo-controlled, parallel two-arm pilot trial in Seoul, Korea. Altogether, 30 diagnosed RA at least 3 months Disease Activity Score 28 joints (DAS28) ≥ 3.2 will be enrolled. Participants are randomly assigned one two groups, experimental group or...

Background: Metaplastic breast cancer (MC) is a rare disease, thus it difficult to study its clinical outcomes. Objective: To investigate whether any clinicopathological or imaging features were associated with outcome in MC. Methods: We retrospectively evaluated the and findings, outcomes of seventy-two pathologically confirmed MCs. then compared these parameters between triple-negative (TNMC) non-TNMCs (NTNMC). Results: Oval round shape, not-circumscribed margin most common findings on...

Motivation: Her2-low breast cancers could benefit from new anti-HER2 therapies. Goal(s): To construct a preoperative prediction model of HER2 expression levels using multiparametric MRI and machine learning (ML) algorithms. Approach: 621 patients were investigated. Four ML methods used to build models based on features predict levels. Results: multiple lesions, spiculated margin, peritumoral edema largest diameter selected the models. performed better for predicting HER2-zero vs....

The purpose of this study was to evaluate the feasibility image fusion between US and supine MRI in breast cancer patients, differences tumor location prone positions.This prospective included 88 patients who underwent an additional (MRsup) sequence following routine (MRpro) for May 2016 December 2017. discrepancies distances from nipple lesion (NLD), skin (SLD), chest wall (CLD) were evaluated MRpro MRsup (MRpro-sup), MRsup-navigated (MRpro-USnav), USnav (MRsup-USnav). Associations...

The breast-conserving operation is the established treatment modality for early breast cancer, with a long-term survival equal to radical surgery (1, 2). Early detection of an ipsilateral tumor recurrence (IBTR) and in regional lymph nodes has beneficial impact on local disease control cancer patients when compared late symptomatic (3). risk factors associated IBTR include younger patient age (4-6), larger size, multifocal multi-centric (7), close or positive margins (6, 8), extensive...

To investigate the usefulness of imaging features for differentiating between small lobular carcinoma in situ (LCIS) and invasive (ILC).It included 52 female with LCISs (median 45 years, range 32-67 years) 180 ILCs 49 36-75 years), longest diameter ≤ 2 cm, who were evaluated January 2012 December 2016. All underwent mammography ultrasonography. Twenty LCIS 150 ILC MRI. The clinical compared, multivariate analysis was performed to identify independent predictors LCIS. Female also subgrouped...

9527 Background: Cancer survivors treated with anthracyclines and/or trastuzumab are at risk for cardiotoxicity. Left ventricular (LV) systolic dysfunction (symptomatic or asymptomatic) represents a Class I indication therapy beta-blockers and angiotensin-converting enzyme inhibitors (ACE-I) angiotensin receptor blockers (ARB) according to American College of Cardiology/American Heart Association heart failure guidelines. We designed this study examine treatment practices patients cancer...

Epipericardial fat necrosis (EPFN) is a relatively rare cause of acute chest pain, with only five pediatric cases having been reported in the English-language medical literature to date. EPFN can be diagnosed based on clinical symptoms pleuritic pain and classic CT features typically ovoid fatty lesions surrounded by rim or capsule mediastinal pericardial areas. Previous studies have that contrast-enhanced MRI detect typical signal changes adults EPFN. We report case using...