A5021813368- Cancer Genomics and Diagnostics
- Renal Transplantation Outcomes and Treatments
- Organ Transplantation Techniques and Outcomes
- Cardiac electrophysiology and arrhythmias
- RNA and protein synthesis mechanisms
- Molecular Biology Techniques and Applications
- Cancer-related Molecular Pathways
- Ion channel regulation and function
- Transplantation: Methods and Outcomes
- Cardiomyopathy and Myosin Studies
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
Instituto de Biomedicina de Sevilla
2016-2022
Universidad de Sevilla
2016-2022
Junta de Andalucía
2019-2022
Hospital Universitario Virgen del Rocío
2020-2021
(1) Background: Graft-cell-free DNA (cfDNA) in the circulation of liver transplant recipients has been proposed as a noninvasive biomarker organ rejection. The aim this study was to detect donor-specific cfDNA (ds-cfDNA) recipient’s serum after either damage or rejection using qPCR-based method. (2) Methods: We qPCR method based on amplification 10 specific insertion–deletion (InDel) polymorphisms circulating diluted recipient cfDNA. ds-cfDNA from 67 patients evaluated during first month...
SCN5A gene variants are associated with both Brugada syndrome and conduction disturbances, sometimes expressing an overlapping phenotype. Functional consequences of assessed by patch-clamp electrophysiology particularly beneficial for correct pathogenic classification related to disease penetrance severity. Here, we identify a novel loss function variant, p.1449Y>H, which presented high complete left bundle branch block, totally masking the typical findings on electrocardiogram. We highlight...
SCN5A gene variants are associated with both Brugada syndrome and conduction disturbances, sometimes expressing an overlapping phenotype. Functional consequences of assessed by patch clamp electrophysiology particularly beneficial for a correct pathogenic classification related to disease penetrance severity. Here, we identify novel loss function variant, p.1449Y>H, which presented high complete left bundle branch block, totally masking the typical findings on electrocardiogram. We...