- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Renal Transplantation Outcomes and Treatments
- Liver Disease Diagnosis and Treatment
- Pancreatitis Pathology and Treatment
- Organ Donation and Transplantation
- Hernia repair and management
- Gallbladder and Bile Duct Disorders
- Gastrointestinal disorders and treatments
- Pancreatic and Hepatic Oncology Research
- Transplantation: Methods and Outcomes
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer Genomics and Diagnostics
- Abdominal vascular conditions and treatments
- Polyomavirus and related diseases
- Hepatitis C virus research
- Viral-associated cancers and disorders
- Congenital Anomalies and Fetal Surgery
- Pediatric Hepatobiliary Diseases and Treatments
- Biliary and Gastrointestinal Fistulas
- Vasculitis and related conditions
- Neurological Complications and Syndromes
- Abdominal Trauma and Injuries
- Renal and Vascular Pathologies
- Soft tissue tumor case studies
Hospital Universitario Virgen del Rocío
2015-2024
Instituto de Biomedicina de Sevilla
2015-2024
Universidad de Sevilla
2015-2023
Hospital Universitario Virgen Macarena
2016
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
2015
Colorectal cancer (CRC) has the second-highest tumor incidence and is a leading cause of death by cancer. Nearly 20% patients with CRC will have metastases at time diagnosis, more than 50% develop metastatic disease during course their disease. A group experts from Spanish Society Medical Oncology, Association Surgeons, Radiation Vascular Interventional Radiology, Nuclear Medicine Molecular Imaging met to discuss provide multidisciplinary consensus on management liver in CRC. The defined...
To compare the rates of R0 resection in pancreatoduodenectomy (PD) for pancreatic and periampullary malignant tumors by means standard (ST-PD) versus artery-first approach (AFA-PD).Standardized histological examination PD specimens has shown that most resections thought to be are R1. "Artery-first approach" is a surgical technique characterized meticulous dissection arterial planes clearing retropancreatic tissue an attempt achieve higher rate R0. date, studies comparing AFA-PD ST-PD...
Health assessment of the transplanted organ is very important due to relationship long-term survival transplant recipients and health maintenance. Nowadays, measurement cell-free DNA from grafts in circulation has been considered a potential biomarker rejection or associated complications an attempt replace reduce liver biopsy. However, methods developed date are expensive extremely time-consuming. Our approach was measure SRY gene, as male biomarker, setting sex-mismatched female donor...
Background Many centers implement everolimus-based immunosuppression in liver transplant patients with hepatocellular carcinoma. We aimed to explore the potential impact of early initiated everolimus on tumor recurrence after transplantation. Methods This study included 192 carcinoma undergoing transplantation among who 64 individuals were prospectively enrolled (2012-2015) and received (ie, started between postoperative day 15 21), whereas remaining 128 acted as historical controls without...
Circulating Tumor Cells (CTCs) are considered a prognostic marker in pancreatic cancer. In this study we present new approach for counting CTCs and CTC clusters patients with cancer using the IsofluxTM System Hough transform algorithm (Hough-IsofluxTM). The Hough-IsofluxTM is based on of an array pixels nucleus cytokeratin expression excluding CD45 signal. Total including free were evaluated healthy donor samples mixed cells (PCCs) from ductal adenocarcinoma (PDAC). manual was used blinded...
Nitric oxide (NO) plays a relevant role during cell death regulation in tumor cells. The overexpression of nitric synthase type III (NOS-3) induces oxidative and nitrosative stress, p53 receptor expression apoptosis hepatoblastoma S-nitrosylation modulates apoptosis. Sorafenib is the unique recommended molecular-targeted drug for treatment patients with advanced hepatocellular carcinoma. present study was addressed to elucidate potential NO Sorafenib-induced HepG2 We determined intra-...
The anatomical variants of the hepatic artery may have important implications for pancreatic cancer surgery. aim our study is to compare outcome following a pancreatoduodenectomy (PD) in patients with or without variant arising from superior mesenteric artery.We reviewed 151 periampullary tumoral pathology. All underwent oncological PD between January 2005 and February 2012. Our series was divided into two groups: Group A: Patients artery; B: artery. We expressed results as mean +/- standard...