A5104239153- Plant Stress Responses and Tolerance
- Plant Molecular Biology Research
- Microbial Metabolic Engineering and Bioproduction
- Plant nutrient uptake and metabolism
- Nanoplatforms for cancer theranostics
- Photosynthetic Processes and Mechanisms
- Plant responses to water stress
- Plant responses to elevated CO2
- Advanced biosensing and bioanalysis techniques
- Metabolism and Genetic Disorders
- Plant Micronutrient Interactions and Effects
- Privacy-Preserving Technologies in Data
- Ginseng Biological Effects and Applications
- Wheat and Barley Genetics and Pathology
- melanin and skin pigmentation
- CRISPR and Genetic Engineering
- Advanced Proteomics Techniques and Applications
- Genetics and Neurodevelopmental Disorders
- Greenhouse Technology and Climate Control
- Venomous Animal Envenomation and Studies
- Lipid metabolism and biosynthesis
- Skin Protection and Aging
- Plant Gene Expression Analysis
- Toxin Mechanisms and Immunotoxins
- Pharmacogenetics and Drug Metabolism
Qingdao Municipal Hospital
2023-2025
Qingdao University
2023-2025
First Affiliated Hospital of Hebei Medical University
2024-2025
The Affiliated Hospital to Changchun University of Chinese Medicine
2025
Ningxia Medical University
2024
Northeast Agricultural University
2009-2024
Tianjin Institute of Industrial Biotechnology
2023-2024
Chinese Academy of Sciences
2023-2024
North China University of Science and Technology Affiliated Hospital
2024
First Affiliated Hospital of Anhui Medical University
2024
Abscisic acid (ABA) is an important plant hormone that plays significant roles in cold tolerance regulation. However, whether ABAimproves by increasing the activities of antioxidant enzymes wheat remains unknown. In this study,the winter variety 'dongnongdongmai 1' ('dn1')afterthe application exogenous ABA under low temperature (0°C, -10°C, -20°C, and -25°C) were investigated. Results showed stress significantly increased H2O2 relative conductivity, whileABA reduced effect. enhanced both...
The basic leucine zipper (bZIP) regulates plant growth and responds to stress as a key transcription factor of the Abscisic acid (ABA) signaling pathway. In this study, TabZIP genes were identified in wheat gene structure, physicochemical properties, cis-acting elements, collinearity analyzed. RNA-Seq qRT-PCR analysis showed that ABA abiotic induced most expression. ectopic expression TaABI5 up-regulated several cold-responsive Arabidopsis. Physiological indexes seedlings different lines...
<title>Abstract</title> Objectives This study aims to disclose the distribution characteristics of CYP2D6 polymorphisms among Han population and provide essential data support future development pharmacogenomics. Methods retrospectively analyzed genetic 6,964 patients with mental disorders who received gene testing at First Hospital Hebei Medical University from March 2021 August 2024.The initial phase experiment entailed genotyping copy number determination CYP2D6, which were performed,...
Although copper (Cu) is an essential micronutrient for plants, a slight excess of Cu in soil can be harmful to plants. Unfortunately, contamination growing problem all over the world due human activities, and poses stress plant development. As one most important biological processes, seed germination sensitive stress. However, little known about mechanism Cu-induced inhibition germination. In present study, we investigated relationship between ABA which predominant regulator at concentration...
Two wheat (Triticum aestivum) cultivars, freeze-tolerant Dongnongdongmai 1 and freeze-sensitive Jimai 22, were used in this study. They grown under field conditions, the leaves sprayed with × 10−5 mol/L ABA distilled water as control respectively at three-true-leaf stage. Application of exogenous increased accumulation carbohydrates both mainly sucrose fructose, except that fructose content decreased 22. Exogenous also enhanced expression key enzyme genes, especially above 0 °C 22 below °C....
1. With the increasing prevalence and escalating complexity of mental disorders, precise medication has become critically important. This necessitates an efficient, accurate, convenient method for drug concentration monitoring to support laboratory personnel clinicians. In this study, three liquid chromatography-tandem mass spectrometry methods were developed validated simultaneously determining quantifying 27 antipsychotics related metabolites in human plasma. The plasma samples subjected...
Background Numerous investigations have underscored the causal effect between chronic pain (CP) and gut microbiota, jointly contributing to onset development of widespread CP. Nonetheless, there was still uncertainty about microbiota regional (CRP). Methods Genome-wide association study (GWAS) summary data microbial taxa (MiBioGen Consortium: 211 microbiotas Dutch Microbiome Project: 207 microbiotas) eight types CRP were used reveal persistent in a specific region body microbiota. A...
Although the regulation of Pi homeostasis by miR399 has been studied in various plant species, its underlying molecular mechanism response to freezing stress is still poorly understood. In this work, we found that expression tae-miR399 and target gene TaUBC24 tillering nodes strong cold-resistant winter wheat cultivar Dongnongdongmai1 (Dn1) was not only significantly altered after severe winters but also responsive short-term stress. physically interacted with TaICE1. Enhanced tolerance...
Freezing stress is one of the main factors limiting growth and yield wheat. In this study, we found that TaMYB4 expression was significantly upregulated in tillering nodes strong cold-resistant winter wheat variety Dongnongdongmai1 (Dn1) under freezing stress. Weighted gene co-expression network analysis, qRT-PCR protein-DNA interaction experiments demonstrated monodehydroascorbate reductase (TaMDHAR) a direct target TaMYB4. The results showed overexpression enhanced tolerance transgenic...
In Federated Learning (FL), blockchain has been extensively used to achieve distributed and tamper-resistant data processing. However, typical Blockchain-based (BFL) rarely considers clients' resource computing limits. High-capacity clients may be sacrificed when all train on the same neural network. This paper proposes a Heterogeneous (BlocFL) model address challenges above. BlocFL replaces central server with consortium blockchain, several networks are employed for local training....
Vertical Federated Learning (VFL) effectively addresses the issue of data isolation, which makes mining secure. Most VFL implementations rely on a single server or third party for training, will be terminated if fails. In addition, model accuracy trained by depends quality client's local features; nevertheless, feature is difficult to verify. There exists chance that features owned client are irrelevant intermediate results submitted inaccurate, such model's seriously affected. order solve...
Liver cirrhosis, a common liver disease, currently lacks specific targeted therapies. This study investigates the potential therapeutic effects of serum circulating proteins on cirrhosis from genetic perspective, and identified six associated plasma (SERPINA1, PSG5, NCAN, APOE, ADH1B, GM2A). To search for drugs with proteins, databases such as DrugBank DGIdb are utilized. Phenome-wide Mendelian Randomization analysis significantly revealed that GM2A exhibited no notable side target SERPINA1...
东北农业大学生命科学学院; 2 东北农业大学农学院, 黑龙江哈尔滨 150030)
Monophosphoryl lipid A, derived from Salmonella minnesota R595, has been used in various adjuvant formulations. Escherichia coli can produce but its structure is different. In this study, E. MG1655 engineered to efficiently the monophosphoryl A. First, 126 genes relevant biosynthesis of fimbriae, flagella, and ECA were deleted MG1655, resulting WQM027. Second, pldA, mlaA, mlaC related phospholipid transport system, gene ptsG carbohydrate phosphotransferase eptA encoding phosphoethanolamine...