A5100350049- Circular RNAs in diseases
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- RNA Interference and Gene Delivery
- Extracellular vesicles in disease
- Aquaculture disease management and microbiota
- RNA Research and Splicing
- RNA modifications and cancer
Shanghai Jiao Tong University
2022
Shanghai Ninth People's Hospital
2022
National Medical Research Center of Dentistry and Maxillofacial Surgery
2018
First Affiliated Hospital of Xinjiang Medical University
2018
Stomatology Hospital
2018
Xinjiang Medical University
2018
Lanzhou University
2012
First Hospital of Lanzhou University
2012
Aberrant proliferation and migration of vascular smooth muscle cells (VSMCs) play an important role in the pathogenesis cardiovascular diseases including coronary heart disease (CHD). MicroRNAs has reported critical roles VSMCs function. The present study was to investigate effects microRNA‑23 (miR-23) on uncover its potential mechanism. Cell viability detected by CCK-8 assay. apoptosis measured flow cytometry. Dual luciferase reporter assay conducted verify whether BCL2L11 is a target gene...
Oral carcinoma, one of the most commonly diagnosed cancers, has a poor prognosis and low survival rate with treatment. In recent years, some studies reported upregulation miRNA-16 (miR-16) in oral whereas other confirmed downregulation miR-16. current study, we aimed to investigate function miR-16 carcinoma.Cell proliferation assay was measured by MTT assay, quantitative real time polymerase chain reaction (qRT-PCR) used evaluate expression miR-16, apoptosis analyzed flow cytometry....
Purpose: Hepatocellular carcinoma (HCC) is the most common malignant tumor of liver cells.Researchers have reported that cancer susceptibility candidate 2 (CASC2), a long non-coding RNA, down-regulated in various cancers, including HCC.Our study aimed to investigate molecular mechanism(s) CASC2 HCC.Materials and Methods: Real-time quantitative PCR (RT-qPCR) was used analyze expression miR-183 HCC tissues cells.The viability SMMC-7721 Huh-7 cells detected through MTT assay.Colony formation...
Cellular microRNAs (miRNAs) are pivotal regulators involved in various biological processes through the post-transcriptional regulation of gene expression. Signaling pathways extensively activated during 12-O-Tetradecanoylphorbol-13-acetate (TPA)-induced differentiation human leukemia cells, but modulation miRNA expression and processing this context has yet to be fully explored. In study, we comprehensively analyzed 10 miRNAs that consistently upregulated TPA-induced cell lines by employing...