A5060609738- Electrochemical sensors and biosensors
- Amino Acid Enzymes and Metabolism
- Electrochemical Analysis and Applications
- Lysosomal Storage Disorders Research
- Metabolism and Genetic Disorders
- Analytical Chemistry and Sensors
- Biomedical Research and Pathophysiology
- Advanced Chemical Sensor Technologies
- Neonatal Health and Biochemistry
- Bee Products Chemical Analysis
- Algal biology and biofuel production
- Carbohydrate Chemistry and Synthesis
- Glycogen Storage Diseases and Myoclonus
- Essential Oils and Antimicrobial Activity
- Dye analysis and toxicity
- Healthcare and Venom Research
- Metabolomics and Mass Spectrometry Studies
- Advanced biosensing and bioanalysis techniques
- Cholesterol and Lipid Metabolism
- Rheumatoid Arthritis Research and Therapies
- Research on Leishmaniasis Studies
- Vitamin C and Antioxidants Research
- Studies on Chitinases and Chitosanases
- Conducting polymers and applications
- Salivary Gland Disorders and Functions
Ege University
2013-2024
Ege Üniversitesi Tıp Fakültesi Hastanesi
2023-2024
Abstract A new electrochemical microbial biosensor system based on Candida tropicalis was developed for the fast detecting of dopamine and epinephrine. immobilized in a carbon paste electrode (CPE) with single wall nanotube (SWCNT). Immobilized cells were used as origin polyphenol oxidase (PPO) to develop voltammetric epinephrine biosensor. Voltammetric determination phenolic compounds such simple technique which is available. Direct oxidation phenols can be used, but potentials this are...
Galactosemia is an inherited disease that occurs as a result of insufficient or no synthesis some enzymes (GALT, GALK, and GALE) in galactose metabolism. Failure to make early diagnosis, especially newborns, can lead severe clinical even fatal consequences. The aim this study develop biosensor for measuring free plasma. immobilization components the developed are screen printed carbon electrode (SCPE), Prussian blue (PB), chitosan (CHIT), Nafion (NAF), gold nanoparticle (GNP), oxidase...
Abstract In this study we report the development of an amperometric cholesterol biosensor based on oxidase from Pseudomonas sp . and catalase immobilized in carbon paste electrode (CPE) modified with multiwall nanotubes (MWCNT) ionic liquid (IL). The working (CPE/MWCNT‐IL/Microorganism (MO)‐Catalase) was characterized by impedance spectroscopy cyclic voltammetry at different stages its construction. This proposed performed linear relationship range 5–600 μM a low detection limit 1.52 μM....
Abstract Background Recently, urinary excretion of the tetrasaccharide 6-α-D-glucopyranosyl-maltotriose (Glc4) has been proposed as a marker for diagnosis and monitoring Pompe disease (PD). We aimed to determine reference intervals reliable decision-making levels urine concentrations infantile- late-onset patients in Turkish population. Methods In this study, nine with PD (five them [LOPD]) 226 healthy individuals (aged 0–64 years) were included. Urine Glc4 determined using...
Aim: The aim of this study is to develop a rapid, precise, specific LC MS method for the determination 3-phenylpyruvic acid, which has an important place in diagnosis phenylketonuria, metabolic disease resulting from Phenylalanine Hydroxylase Enzyme deficiency.
 Materials and Methods : Analytical measurements were made with Acqutiy UPLC (Waters Xevo TQD). chromatographic separation was operated on Acquity Phenyl column (50 mm × 2.1 mm, 1.7 μm) gradient elutionusing 0.1% formic acid...
Objectives: Glutathione (GSH, L-γ-glutamyl-L-cysteinyl-glycine), one of the major cellular antioxidants, is an important non-protein intracellular physiological antioxidant with sulphhydryl groups for detoxification reactive oxygen species (ROS) in all living organisms. GSH deficiency has been shown to be associated many human diseases, including cardiovascular, immune and ageing arthritis diabetes. Therefore, development accurate, reliable sensitive method determination biological fluids...
The Sars-CoV-2 virus causes the COVID-19 disease, which is characterized by high mortality rate and symptoms such as severe acute respiratory failure. However, it has been proven that 3-chymotrypsin-like protease (3Clpro) enzyme, plays a key role in replication of virus, can be inhibited certain natural compounds with flavonoid structure. Flavonoids interact active site resulting enzyme inhibition. In this project, aim was to determine inhibitory concentrations molecules on 3Clpro obtain...
Elevated levels of cholesterol in the bloodstream, also referred to as hypercholesterolemia, pose a significant risk for onset cardiovascular and cerebrovascular diseases. Oxysterols, cholesterol-derived oxidized compounds that form enzymatically or non-enzymatically, contribute development atherosclerosis coronary artery disease. This study aimed examine critical oxysterol children adolescents with hypercholesterolemia explore correlation between these levels, oxidative stress, progression....
Aim/Objective: The primary goal of this study is to explore the impact consistent treatment on key disease marker, Lyso-Gb1. Additionally, research aims evaluate influence splenectomy Lyso-gb1 concentrations within patient group. Materials and Methods: 37 patients diagnosed with GD were categorized based compliance into three groups: 28 in regular group, who consistently followed their treatment; 6 irregular inconsistent adherence; 3 untreated A control group 33 healthy individuals without...