A5080051180- Total Knee Arthroplasty Outcomes
- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- Bone health and treatments
- Biomarkers in Disease Mechanisms
- Cancer Diagnosis and Treatment
- Hip and Femur Fractures
- Anesthesia and Pain Management
- Cardiac, Anesthesia and Surgical Outcomes
- Surgical site infection prevention
- Opioid Use Disorder Treatment
- Pain Management and Opioid Use
- COVID-19 and healthcare impacts
- Bone Metabolism and Diseases
- Spine and Intervertebral Disc Pathology
- Pelvic and Acetabular Injuries
- Hip disorders and treatments
- Bone fractures and treatments
- Spinal Fractures and Fixation Techniques
- Medical Imaging Techniques and Applications
- Innovations in Medical Education
- Infectious Diseases and Tuberculosis
- Musculoskeletal Disorders and Rehabilitation
- Shoulder Injury and Treatment
- Knee injuries and reconstruction techniques
University of Arkansas for Medical Sciences
2017-2025
Springer Nature (Germany)
2022
American Academy of Orthopaedic Surgeons
2022
OrthoCarolina Research Institute
2018-2022
OrthoCarolina
2017-2018
Stanford University
2018
Hospital for Special Surgery
2018
Zimmer Biomet (United States)
2018
Washington University in St. Louis
2014-2017
Barnes-Jewish Hospital
2013-2015
The COVID-19 global pandemic has upended nearly every medical discipline, dramatically impacted patient care and had far-reaching effects on surgeon education. In many areas of the country, elective orthopedic surgery completely stopped to ensure that resources are available for critically ill minimize spread disease. is forcing around world re-evaluate existing processes organizations adapt carry out business, which medicine education not immune. Most national international conferences,...
BackgroundIn response to the COVID-19 pandemic, hospitals in United States were recommended stop performing elective procedures. This stoppage has led cancellation of a large number hip and knee arthroplasties. The effect this on patients' physical mental economic health is unknown.MethodsA survey was developed by AAHKS Research Committee assess pain, anxiety, function, ability patients undergo delayed operation. Six institutions conducted 360 who had have arthroplasty cancelled between...
Denosumab is an anti-RANKL Ab that potently suppresses bone resorption, increases mass, and reduces fracture risk. Discontinuation of denosumab causes rapid rebound resorption loss, but the molecular mechanisms are unclear. We generated humanized RANKL mice treated them with to examine cellular conditions associated resorption. suppressed both osteoclast osteoblast numbers in cancellous mice. The decrease number was not changes progenitors marrow. Long-term, short-term, administration...
Introduction PROMIS® Computer Adaptive Testing (CAT) is a testing tool for tracking patient-reported outcome measures (PROM) with goal to improve individual and population outcomes. Patients’ health literacy (HL) may affect how they are able complete PROM. We hypothesized that patients low HL were less likely both surveys do so via online patient portal (OPP). Methods A retrospective cohort study of 3926 orthopaedic in rural state was performed. Completion rate completion method subjected...
Two-stage reimplantation arthroplasty is a commonly used approach for treating chronic periprosthetic joint infections. A prereimplantation threshold value of erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) to determine infection eradication the proper timing remains ill defined. We theorized that rather than specific numeric threshold, percentage improvement in these serology markers might improve diagnostic accuracy determining reimplantation.We investigated if (1)...
Background: Despite known surgical volume reductions in 2020 during the height of COVID-19 pandemic, no study has fully quantified impact pandemic on number elective inpatient total hip (THA) and knee arthroplasty (TKA) cases. The purpose present was to analyze THA TKA case volumes United States pandemic. Methods: Premier Healthcare Database utilized identify adults undergoing primary or from January 2017 December 2020. National Inpatient Sample cross-referenced provide nationwide...
Custom cutting guides (CCGs; sometimes called patient-specific instrumentation [PSI]) in total knee arthroplasty (TKA) use preoperative three-dimensional imaging to fabricate blocks specific a patient's native anatomy.The purposes of this study were determine if CCGs (1) improve clinical outcomes as measured by UCLA activity, SF-12, and Oxford scores; (2) coronal mechanical alignment versus standard guides.This was retrospective cohort patients undergoing primary TKA using the same...
Abstract As we age, our bones undergo a process of loss, often accompanied by muscle weakness and reduced physical activity. This is exacerbated decreased responsiveness to mechanical stimulation in aged skeleton, leading the hypothesis that plays an important role age‐related bone loss. Piezo1, mechanosensitive ion channel, critical for homeostasis mechanotransduction. Here, observed decrease Piezo1 expression with age both murine human cortical bone. Furthermore, loss osteoblasts...
Abstract Background Robotic-assisted TKA continues to see wider clinical use, despite limited knowledge of its impact on patient satisfaction and implant survival. Most studies date have presented small cohorts came from single-surgeon or single-center experiences. Therefore, a population-level comparison revision rates between robotic-assisted conventional in the registry setting may help arthroplasty surgeons better define whether robotic assistance provides meaningful advantage compared...
Breast cancer bone metastases increase fracture risk and are a major cause of morbidity mortality among women. Upon colonization by tumor cells, the microenvironment undergoes profound reprogramming to support progression, which disrupts balance between osteoclasts osteoblasts leads lesions. A deeper understanding processes mediating this could help develop interventions for treating patients with metastases. Here, we demonstrated that osteocytes (Ot) in established breast metastasis...
The aims of this retrospective study were to compare the mid-term outcomes following revision total knee replacement (TKR) in 76 patients (81 knees) < 55 years age with those a matched group primary TKRs based on age, BMI, gender and comorbid conditions. We report activity levels, functional scores, rates complications. Compared undergoing TKR, TKR had less improvement mean Knee Society function scores (8.14 (-55 +60) vs 23.3 points (-40 +80), p 0.001), similar UCLA level (p = 0.52), minor...