John C. Clohisy

ORCID: 0000-0001-7040-616X
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About
Contact & Profiles
Research Areas
  • Orthopaedic implants and arthroplasty
  • Hip disorders and treatments
  • Total Knee Arthroplasty Outcomes
  • Orthopedic Infections and Treatments
  • Cardiac Valve Diseases and Treatments
  • Shoulder Injury and Treatment
  • Hip and Femur Fractures
  • Bone and Joint Diseases
  • Musculoskeletal synovial abnormalities and treatments
  • Pelvic and Acetabular Injuries
  • Sports injuries and prevention
  • Lower Extremity Biomechanics and Pathologies
  • Bone Metabolism and Diseases
  • Osteoarthritis Treatment and Mechanisms
  • Venous Thromboembolism Diagnosis and Management
  • Shoulder and Clavicle Injuries
  • Knee injuries and reconstruction techniques
  • Health Systems, Economic Evaluations, Quality of Life
  • Atrial Fibrillation Management and Outcomes
  • Pharmacogenetics and Drug Metabolism
  • Cardiac, Anesthesia and Surgical Outcomes
  • Musculoskeletal pain and rehabilitation
  • Telemedicine and Telehealth Implementation
  • Surgical site infection prevention
  • Musculoskeletal Disorders and Rehabilitation

Washington University in St. Louis
2016-2025

University of Wisconsin–Madison
2024

Mayo Clinic in Florida
2013-2024

University of Iowa
2024

Hospital for Special Surgery
2023-2024

WinnMed
2024

Twin Cities Orthopedics
2024

Building Engineering and Science Talent
2022

Barnes-Jewish Hospital
2011-2021

Jewish Hospital
2009-2021

Clohisy, John C. MD; Carlisle, Beaulé, Paul E. Kim, Young-Jo Trousdale, Robert T. Sierra, Rafael J. Leunig, Michael Schoenecker, Perry L. Millis, B. MD Author Information

10.2106/jbjs.h.00756 article EN Journal of Bone and Joint Surgery 2008-11-01

The 2016 Warwick Agreement on femoroacetabular impingement (FAI) syndrome was convened to build an international, multidisciplinary consensus the diagnosis and management of patients with FAI syndrome. 22 panel members 1 patient from 9 countries 5 different specialties participated in a 1-day meeting 29 June 2016. Prior meeting, 6 questions were agreed on, recent relevant systematic reviews seminal literature circulated. Panel gave presentations topics at Sports Hip , open held UK 27–29...

10.1136/bjsports-2016-096743 article EN British Journal of Sports Medicine 2016-09-14

Femoroacetabular impingement (FAI) is considered a cause of labrochondral disease and secondary osteoarthritis. Nevertheless, the clinical syndrome associated with FAI not fully characterized. We determined history, functional status, activity physical examination findings that characterize FAI. prospectively evaluated 51 patients (52 hips) symptomatic Evaluation exam, previous treatments was performed. Patients completed demographic validated hip questionnaires (Baecke et al., SF-12,...

10.1007/s11999-008-0680-y article EN Clinical Orthopaedics and Related Research 2009-01-06

Background: The clinical presentation of a labral tear the acetabulum may be variable, and diagnosis is often delayed. We sought to define characteristics associated with symptomatic acetabular tears by reviewing group patients who had an arthroscopically confirmed diagnosis. Methods: retrospectively reviewed records for sixty-six consecutive (sixty-six hips) documented that been hip arthroscopy. prospectively recorded demographic factors, symptoms, physical examination findings, previous...

10.2106/jbjs.d.02806 article EN Journal of Bone and Joint Surgery 2006-07-01

Quality of health care and safety have been emphasized by various professional governmental groups. However, no standardized method exists for grading reporting complications in orthopaedic surgery. Conclusions regarding outcomes are incomplete without a standardized, objective complication scheme applied concurrently. The general surgery literature has the Clavien-Dindo classification that meets above criteria.We asked whether previously reported would show high intraobserver interobserver...

10.1007/s11999-012-2343-2 article EN Clinical Orthopaedics and Related Research 2012-04-18

Radiographic evaluation provides essential information regarding the diagnosis and treatment of musculoskeletal disorders. We evaluated ability hip specialists to reliably identify important radiographic features make a based on plain radiographs alone. Five one fellow performed blinded review 25 control hips, hips with developmental dysplasia (DDH), 27 femoroacetabular impingement (FAI). On two separate occasions, readers assessed acetabular version, inclination depth, position femoral head...

10.1007/s11999-008-0626-4 article EN Clinical Orthopaedics and Related Research 2008-12-01

TKA is among the fastest growing interventions in medicine, with procedure incidence increasing most younger patients. Global knee scores have a ceiling effect and do not capture presence of difficulty or dissatisfaction specific activities important to patients.We quantified degree residual symptoms functional deficits young patients who had undergone TKA.In national multicenter study, we 661 (mean age, 54 years; range, 19-60 61% female) at 1 4 years after primary TKA. To eliminate observer...

10.1007/s11999-013-3229-7 article EN Clinical Orthopaedics and Related Research 2013-09-23

Background: Symptomatic femoroacetabular impingement (FAI) is associated with hip pain, functional limitations, and secondary osteoarthritis. There limited information from large patient cohorts defining the specific population affected by FAI. Establishing a cohort will facilitate identification of “at-risk” patients provide for ongoing clinical research initiatives. The authors have therefore established multicenter, prospective, longitudinal undergoing surgery symptomatic Purpose: To...

10.1177/0363546513488861 article EN The American Journal of Sports Medicine 2013-05-13

Despite the successes of hip arthroscopy, clinical failures do occur, and identifying risk factors for failure may facilitate refinement surgical indications treatment. Knowledge regarding reasons treatment also improve decision making.We (1) characterized patients whose symptoms recurred after arthroscopy necessitating a revision preservation procedure or arthroplasty, (2) determined etiologies failure, (3) reported profile procedures.In prospective database 1724 consecutive surgeries, we...

10.1007/s11999-013-3015-6 article EN Clinical Orthopaedics and Related Research 2013-05-01

Background: Current literature describing the periacetabular osteotomy (PAO) is mostly limited to retrospective case series. Larger, prospective cohort studies are needed provide better clinical evidence regarding this procedure. The goals of current study were (1) report minimum 2-year patient-reported outcomes (pain, hip function, activity, overall health, and quality life), (2) investigate preoperative disease characteristics as predictors outcomes, (3) rate early failures reoperations in...

10.2106/jbjs.15.00798 article EN Journal of Bone and Joint Surgery 2017-01-04

The purpose of this study was to determine the indications for contemporary revision hip surgery in a consecutive series patients. We retrospectively reviewed clinical records and radiographs 439 surgeries done between 1996 2003. Fifty-five percent were aseptic loosening, 14% instability, 13% osteolysis around well-fixed implant, 7% infection, 5% periprosthetic fracture, 3% conversion hemiarthroplasty, 1% psoas impingement, loose recalled implants, implant fracture. As expected, loosening...

10.1097/01.blo.0000150126.73024.42 article EN Clinical Orthopaedics and Related Research 2004-12-01

In this study, we compared magnetic resonance arthrography results with hip arthroscopy findings to assess the diagnostic value of imaging technique in evaluating acetabular labral tears and concurrent articular pathology. One hundred one consecutive patients (102 hips) a clinical diagnosis tear were assessed using had after failing improve nonoperative treatment. Magnetic detected 71 93 (76%) (92 patients) five false positive studies (4.9%). Articular cartilage diagnosed by confirmed 64...

10.1097/01.blo.0000150125.34906.7d article EN Clinical Orthopaedics and Related Research 2004-12-01

Radiographic evaluation of the anterolateral femoral head-neck junction is essential in diagnosing cam femoroacetabular impingement. We hypothesized frog-leg lateral radiograph can accurately assess offset abnormalities associated with reviewed radiographs 61 hips treated for impingement and 24 asymptomatic control hips. To characterize anatomy junction, head sphericity, alpha-angle Nötzli et al, were measured on all radiographs. Asphericity was detected more frequently radiographic views...

10.1097/blo.0b013e3180f60b53 article EN Clinical Orthopaedics and Related Research 2007-06-22

The optimal treatment of severe acetabular dysplasia with subluxation the femoral head or presence a secondary acetabulum remains controversial. purpose this study was to analyze extent surgical correction and early clinical results obtained Bernese periacetabular osteotomy for severely dysplastic hips in adolescent young adult patients.Sixteen thirteen patients an average age 17.6 years (range, 13.0 31.8 years) were classified as having (Group IV V according Severin classification). Eight...

10.2106/jbjs.d.02093 article EN Journal of Bone and Joint Surgery 2005-02-01

Destruction of cartilage in osteoarthritis is a direct effect an imbalance between catabolic and anabolic activities the tissue. While great deal known about catabolism, we sought to determine biochemical basis activity.Cartilage was isolated from normal osteoarthritic patients subjected both cell explant culture. mRNA expression levels growth differentiation factors bone morphogenetic protein-2 (BMP-2), BMP-4, BMP-6, cartilage-derived protein-1 (CDMP-1), connective tissue factor (CTGF),...

10.2106/00004623-200300003-00011 article EN Journal of Bone and Joint Surgery 2003-01-01

Background: Significant controversy exists regarding the causes of premature, natural hip-joint failure. Identification these may guide future investigations targeting prevention this disorder. The aims study were to: (1) determine and characterize structural abnormalities associated with failure, (2) analyze disease progression in contralateral hips patients femoroacetabular impingement deformities. Methods: We analyzed 604 (710 hips) from three different medical centers who underwent...

10.2106/jbjs.j.01734 article EN Journal of Bone and Joint Surgery 2011-05-04

Background: Acetabular dysplasia is recognized as a cause of early degenerative hip osteoarthritis. The purpose this study was to prospectively determine the clinical presentation symptomatic acetabular in skeletally mature patients. Methods: Fifty-seven consecutive patients with total sixty-five hips were diagnosed on basis history, physical examination, and radiographs. These fifty-seven enrolled followed for minimum twenty-four months postoperatively. Results: group included forty-one...

10.2106/jbjs.j.01735 article EN Journal of Bone and Joint Surgery 2011-05-04

Summary Cytochrome P-450 2C9 (CYP2C9) polymorphisms (CYP2C9*2 and CYP2C9*3) reduce the clearance of warfarin, increase risk bleeding, prolong time to stable dosing. Whether prospective use a retrospectively developed algorithm that incorporates CYP2C9 genotype nongenetic factors can ameliorate propensity bleeding delay in achieving warfarin dose is unknown. We initiated therapy 48 orthopedic patients tailored following variables: genotype, age, weight, height, gender, race, simvastatin or...

10.1160/th04-08-0542 article EN Thrombosis and Haemostasis 2005-01-01
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