- HIV/AIDS drug development and treatment
- HIV Research and Treatment
- Pharmaceutical Practices and Patient Outcomes
- Cultural Heritage Materials Analysis
- Ethics in Clinical Research
- Advanced Chemical Sensor Technologies
- HIV/AIDS Research and Interventions
- HIV-related health complications and treatments
- Palliative Care and End-of-Life Issues
- Atrial Fibrillation Management and Outcomes
- Healthcare Systems and Technology
- Meta-analysis and systematic reviews
- Patient Satisfaction in Healthcare
- Breastfeeding Practices and Influences
- Mental Health and Patient Involvement
- Dysphagia Assessment and Management
- Management of metastatic bone disease
- Bone health and osteoporosis research
- Family and Patient Care in Intensive Care Units
- Potassium and Related Disorders
- Treatment of Major Depression
- Takotsubo Cardiomyopathy and Associated Phenomena
- Healthcare professionals’ stress and burnout
- Health Sciences Research and Education
- Spinal Hematomas and Complications
Palmerston North Hospital
2024
Cardiff University
2024
St Vincent's Hospital Sydney
1993-2023
UNSW Sydney
1997-2023
St Vincent's Clinic
2018-2023
The University of Notre Dame Australia
2021
Nottingham University Hospitals NHS Trust
2021
Queen's Medical Centre
2021
St Vincent's Hospital
1997-2018
Prince of Wales Hospital
2001
Objectives To investigate oral health status and abnormalities in older adults admitted acutely to the hospital explore association with common medical comorbidities. Design Cross‐sectional study. Setting Hospital. Participants All individuals aged 70 (mean age 84.4, 61.4% female) a geriatric service over 3 months (N = 202). Measurements In‐person assessment using Oral Health Assessment Tool ( OHAT ) (range 0–2, 2 poorest) for lips, tongue, gums soft tissue, saliva, teeth, dentures,...
Human immunodeficiency virus type 1 (HIV-1) resistant to the nonnucleoside reverse transcriptase inhibitor nevirapine and nucleoside analogue zidovudine was transmitted from a homosexual man his sex partner. The source patient had commenced combination therapy 2.5 years prior partner's primary HIV infection. He received both therapies for 7 months, then discontinued treatment, continuing receive monotherapy further 16 months. ceased 6 months before time of seroconversion. Analysis major...
deprescribing habits among physicians managing older, frailer, cognitively impaired patients have not been well investigated.an anonymised electronic survey was disseminated to all members of an international geriatric society/local advanced trainee network (N = 930). This comprised a Likert-scale analysis factors influencing desprescribing, and five case vignettes, detailing patient with progressive cognitive impairment dependency, on background ischaemic heart disease hypertension.among...
To establish prevalence, sequelae and documentation of potentially inappropriate medication (PIM) use in older hospital in-patients.Notes all patients ≥65 years old, admitted to our tertiary teaching (January 2013), were retrospectively reviewed, the Screening Tool Older Persons' Prescriptions applied.Amongst 534 patients, 54.8% (284) on ≥1 PIM at admission, 26.8% multiple; 60.8% discharged a PIM. Six percent admissions attributable PIM; falls associated with risk therapies commonest...
Accurate population-based data regarding hospital-based care utilisation by older persons during their last year of life are important in health services planning. We investigated patterns acute service use at the end life, amongst decedents New South Wales (NSW), Australia. Data from all aged ≥70 years who died state NSW Australia 2007 were included. Several measures assessed retrospectively linked comprising for registered deaths, cause death, hospital (NSW Admitted Patient Collection...
Objective: To evaluate treatment response, durability and tolerance of a four-drug regimen including saquinavir ritonavir in combination with either zidovudine/lamivudine or stavudine/lamivudine. Design: Observational cohort HIV-positive individuals. Methods: Viral load, CD4+ CD8+ T lymphocyte counts were assessed at intervals 1–3 months subjects commencing therapy between July 1996 November 1996. Adverse events evaluated as well risk factors for therapeutic failures. Results: A group 56...
Objectives: The aim of this paper is to report the use electroconvulsive therapy (ECT) successfully treat depression in a 97-year-old woman, and discuss safety efficacy ECT very old. Methods: A case review literature on old presented. Results: subject recovered fully from her but suffered serious adverse event (fractured femur) during course ECT. Relatively few publications were found. majority articles concerned patients aged between 65 85, with one study including up age 96. Conclusions:...
The roles of clinicians and investigators have been increasingly intertwined over the past 30 years. This study explores tensions performing both in context HIV medicine. Clinicians, who are also investigators, were interviewed Australia during course an intensive phase II clinical trial. Clinicians described positive negative outcomes participating trials. considered it beneficial to be able offer potentially effective therapies at early stage their patients found research broadened work...
Paint samples received at a forensic laboratory usually consist of small chips or smears. Analytical methods, therefore, must be capable producing significant information from microsamples. Infrared (IR) spectroscopy is one the most useful and powerful tools for this purpose. Its microsampling capabilities are well established it provides molecular structure on both organic inorganic constituents multicomponent mixtures such as paint layers. IR can applied to identifying probable sources...
Osteoporosis is underdiagnosed and undertreated in Australia, especially hospitalised patients. We aimed to improve bone health management geriatric inpatients by introducing a mnemonic into discharge summaries.A retrospective review of patients discharged from our unit was performed before after intervention. Outcomes assessed were as follows: vitamin D measurement, protection medication communication general practitioners.Sixty-one included the initial audit, 82 reaudit. There an increase...
Abstract Purpose Older patients are at high risk for poor outcomes after an acute hospital admission. The Transitional Aged Care Programme (TACP) was established by the Australian government to provide a short-term care service aiming optimise functional independence following discharge. We aim investigate association between multimorbidity and readmission amongst on TACP. Methods Retrospective cohort study of all TACP over 12 months. Multimorbidity defined using Charlson Comorbidity Index...
Abstract Objective Neonatal breastfeeding is reported to have advantages for both physical and psychological well-being, including decreased incidence of infections, improved neurodevelopmental outcomes a variety lifelong health benefits. In some cases inadequate can lead malnutrition hypernatraemic dehydration. While the impact on from dehydration well reported, longer neurocognitive quality life (QoL) are rarely documented. Method We present profiles two paediatric where significant brain...
Bacillus Calmette-Guerin (BCG) is a live-attenuated strain of Mycobacterium bovis (M bovis), originally developed as vaccine against tuberculosis.It also used in the treatment bladder cancer.We present case disseminated BCG-osis which was only discovered at post-mortem.An 89-year-old male admitted to tertiary referral centre inner Sydney December 2015 with fevers, night sweats, exertional dyspnoea and 8 kg weight loss.The patient progressive type 1 respiratory failure requiring non-invasive...
Abstract Background Appropriate antibiotic stewardship is of great importance given increasingly high rates microbial resistance and the vulnerability older persons to adverse drug effects. Aim To assess prescriber compliance with Antibiotic Therapeutic Guidelines when prescribing for patients admitted our geriatric service, if deficits were identified in initial audit, conduct an educational intervention, re‐audit planned thereafter. Method Patients Medical Admissions Unit ( MAU ) treated...
<b><i>Background:</i></b> The association between gait and cognition, their combined impact on postural stability may underlie the increased fall risk in older adults with dementia. However, there are few interventions to improve functional mobility reduce risks people cognitive impairment. <b><i>Objectives:</i></b> This study aims investigate feasibility acceptability of a Safe Mobilisation Program for cognitively impaired higher level...
Hyponatremia is a common electrolyte disorder in older people. We investigated management of hyponatremia, and the association between admission fall at admission, other adverse outcomes, in-patients, group less extensively studied to date. This retrospective observational study included consecutive medical patients ≥75 years admitted over six-week period. Primary outcome measure was admission. Secondary outcomes fractures, functional dependence/assistance mobilize discharge, death. Amongst...
Community HIV\AIDS Trial Network, University New South Wales, Level 2, 376 Victoria Street, NSW 2010, Australia.