- Stroke Rehabilitation and Recovery
- Mollusks and Parasites Studies
- Ideological and Political Education
- Child Abuse and Trauma
- Child and Adolescent Psychosocial and Emotional Development
- Cerebral Palsy and Movement Disorders
- Chinese history and philosophy
- Adolescent Sexual and Reproductive Health
- Balance, Gait, and Falls Prevention
- Dialysis and Renal Disease Management
- SARS-CoV-2 and COVID-19 Research
- Atomic and Subatomic Physics Research
- Physical Activity and Health
- Sexual Assault and Victimization Studies
- Migration, Health and Trauma
- Global Health Workforce Issues
- Histone Deacetylase Inhibitors Research
- Neurological Disease Mechanisms and Treatments
- Racial and Ethnic Identity Research
- Hepatitis B Virus Studies
- Osteomyelitis and Bone Disorders Research
- Protein Degradation and Inhibitors
- Transcranial Magnetic Stimulation Studies
- Anesthesia and Neurotoxicity Research
- Blood groups and transfusion
Ghent University
2013-2025
Jiangxi Academy of Agricultural Sciences
2024
Animal Science Research Institute
2024
SK Life Science (United States)
2024
Guangzhou First People's Hospital
2024
Guangzhou Medical University
2024
Zhengzhou University
2010-2023
Université Libre de Bruxelles
2023
Clemson University
2023
Nanjing Medical University
2005-2022
Summary Aims To evaluate the effectiveness of repetitive transcranial magnetic stimulation ( rTMS ) on motor recovery after stroke using a prospective, double‐blind, randomized, sham‐controlled study. Methods Patients with unilateral subcortical infarction in middle cerebral artery territory within 1 week onset were enrolled. The patients randomly divided into an treatment group and sham group. We performed high‐frequency or two groups. Motor functional scores assessed pre‐ post‐ /sham at...
Background Stroke is a major health threat and the leading cause of mortality disability in China. The aims this study were to identify possible influencing factors health-related quality life (HRQoL) its domain-specific contents stroke patients rural areas Methods A total 1,709 aged 36–79 years from baseline data Henan Rural Cohort ( n = 39,259) included cross-sectional study. Chinese version European Quality Life Five Dimension (including mobility, self-care, usual activities,...
Avian leukosis virus subgroup K (ALV-K) is a new of avian (ALV) that was first identified in Chinese native chickens recent years. To further understand the molecular epidemiology and evolutionary diversity ALV-K, this study investigated 73,664 chicken plasma samples collected from Jiangxi flocks. The results showed ALV-J most predominant ALV subtype chickens, with high positivity rate 4.34%. From 2021 to 2023, there gradual upward trend proportion positive numbers ALV-K among ALV-positive...
Most of the individuals infected with SARS coronavirus (SARS-CoV) spontaneously recovered without clinical intervention. However, immunological correlates associated patients' recovery are currently unknown. In this report, we have sequentially monitored 30 patients over a two-year period to characterize temporal changes in SARS-CoV-specific antibody responses as well cytotoxic T cell (CTL) responses. We found persistence robust and CTL all study subjects throughout period, moderate decline...
The aim of this study was to develop a quick and economical method for the diagnosis fungal keratitis. Corneal scrapings were obtained from consecutive patients (n = 165) with clinically suspected keratitis used culture prepare two smears. Potassium hydroxide stain followed by calcofluor white added one smear Giemsa second. In comparison results, sensitivity potassium wet mounts 81.0% following addition 96.6% in diagnosing keratitis, whereas using 39.7% 98.3%. detected 23 cases bacterial...
Our study aimed to figure out brain functional reorganization evidence after repetitive transcranial magnetic stimulation (rTMS) using the resting-state resonance imaging (rsfMRI).Twelve patients with unilateral subcortex lesion in middle cerebral artery territory were recruited. Seven of them received a 10-day rTMS treatment beginning at about 5 days stroke onset. The remaining five sham treatment. RsfMRI and motor scores obtained before or rTMS.The group showed recovery according...
Objectives The caregiving experience includes both caregiver burdens and benefits finding. However, the obtained by family caregivers of stroke survivors in Chinese community dwellings are unknown. objective this study was to explore experienced dwellings. Design A qualitative descriptive design used, fulfilling consolidated criteria for Standards Reporting Qualitative Research reporting guidelines. Semi-structured interviews were conducted with 20 survivors. audiotaped, transcribed...
Inhibition of estrogen receptor alpha (ERα) signaling is an established therapeutic approach for the treatment ER-positive (ER+) breast cancers, but new strategies are urgently needed to overcome clinical resistance. In present study, we describe discovery and extensive evaluation ERD-12310A as exceptionally potent orally efficacious PROTAC degrader ERα. achieved a DC
Objective: The rising rate of suicidal behavior among adolescents is a growing concern, and sex differences may induce differential exposure to prescription drug misuse or behavior. We estimated, Chinese adolescents, (1) the prevalence nonmedical use drugs, ideation suicide attempts; (2) whether drugs was independently associated with (3) there were in associations. Methods: This secondary analysis data drawn from 2015 National School-based Adolescents Health Survey. A total 94,911 students...
Despite the development of highly effective therapies for treatment estrogen receptor α (ERα)-positive human breast cancer, clinical resistance to current requires novel therapeutic strategies. Herein, we report discovery ERD-1233 as a potent and orally efficacious ERα degrader designed using PROTAC technology. was developed based on Lasofoxifene ER binding moiety cereblon ligand through extensive optimization linker. potently effectively reduces protein in vitro achieves excellent oral...
Objective. We evaluated the whole-spine computed tomography (CT) findings in patients with synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome to improve our understanding of this rare disease. Methods. Whole-spine CT images obtained 69 SAPHO were reviewed. For each individual, a total 25 vertebrae for distribution affected vertebrae, manifestations vertebral lesions, symmetry location lesions on involvement pattern, narrowing adjacent intervertebral disc space....
Objective. Stroke survivors with motor deficits often have pyramidal tract atrophy caused by degeneration of corticospinal fibers. The authors hypothesized that the degree correlates severity impairment in patients chronic stroke and predicts response to rehabilitation training. Methods. They performed a post hoc analysis 42 hemiparetic (>6 months) who had been randomized either 6 weeks bilateral arm training rhythmic auditory cueing (BATRAC) or dose-matched therapeutic exercise (DMTE)....
Prehypertension is common in China and associated with an increased risk of cardiovascular disease. The present study estimated the current prevalence prehypertension its association clustering other modifiable factors (CRFs) among adults suburban Beijing.A cross-sectional survey a representative sample 19 003 aged 18 to 76 years was carried out 2007. Questionnaire data information on blood pressure, anthropometric characteristics, laboratory measurements were collected.The age-standardized...
Importance A better understanding of the psychosocial health resettled child and adolescent refugees associated premigration postmigration factors may help this population integrate effectively. Objective To estimate associations multidomain with after resettlement among young different ages. Design, Setting, Participants This cross-sectional study used wave 3 data from Building a New Life in Australia (BNLA) cohort study, as they represented first time BNLA included module targeting...
Abstract Background The differential diagnosis of diffuse cystic lung disease (DCLD) is a clinical challenge. We wish to analyze the distribution etiology DCLD based on data from single lymphangioleiomyomatosis (LAM) clinic. Methods All patients at LAM Clinic Peking Union Medical College Hospital between January 2006 and December 2019 were analyzed. Information demographic, clinical, radiological, pathological features was collected. Results A total 1010 with CT scan evaluated. sum...