A5067299257- Mental Health Treatment and Access
- Mental Health Research Topics
- Digital Mental Health Interventions
- Child and Adolescent Psychosocial and Emotional Development
- COVID-19 and Mental Health
- Hormonal Regulation and Hypertension
- Sleep and related disorders
- Maternal Mental Health During Pregnancy and Postpartum
- Bipolar Disorder and Treatment
- Atherosclerosis and Cardiovascular Diseases
- Tryptophan and brain disorders
- Receptor Mechanisms and Signaling
- Treatment of Major Depression
- Adolescent and Pediatric Healthcare
- Health disparities and outcomes
- Suicide and Self-Harm Studies
- Lipoproteins and Cardiovascular Health
- Cardiac Health and Mental Health
- Fatty Acid Research and Health
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Long-Term Effects of COVID-19
- Psychological Well-being and Life Satisfaction
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Restless Legs Syndrome Research
- Chemokine receptors and signaling
Shenzhen Nanshan Center for Chronic Disease Control
2019-2025
Hainan Medical College Hospital
2025
Sichuan University
2024
Sun Yat-sen University
2021-2023
Bridge University
2020
Huazhong University of Science and Technology
2008-2016
Union Hospital
2008-2016
Union Hospital
2008-2016
Wuhan General Hospital of Guangzhou
2011
To identify the factors influencing pyrotinib-induced severe diarrhea and to establish a risk prediction nomogram model. The clinical data of 226 patients received pyrotinib from two medical institutions January 2019 December 2023 were analysed retrospectively. A training set was made up 167 Hainan Cancer Hospital, external validation 59 West Central Hospital. Univariate multivariate logistic regression analysis used independent diarrhea, model constructed, which verified on in set. History...
Objective The objective of this research was to evaluate the impact federal, public health and social support programs on national suicide rates in Canada. Design Cross-sectional study. Setting Canadian National Database (i.e., Statistics Canada) Statista. Participants Population-level data, economic consumer market data. Main Outcome Measures Suicide mortality population data unemployment were obtained from available statistical databases (e.g. Canada). We quantified rate by dividing total...
The coronavirus disease 2019 (COVID-19) pandemic represents an unprecedented threat to mental health. Herein, we assessed the impact of COVID-19 on subthreshold depressive symptoms and identified potential mitigating factors.Participants were from Depression Cohort in China (ChiCTR registry number 1900022145). Adults (n = 1722) with enrolled between March October a 6-month, community-based interventional study that aimed prevent clinical depression using psychoeducation. A total 1506...
The presence of heterogenous somatic symptoms frequently obscures the recognition depression in primary care. We aimed to explore association between and subthreshold (SD) Major Depressive Disorder (MDD), as well determine predictive potential identifying SD MDD care.Data were derived from Depression Cohort China study (ChiCTR registry number: 1900022145). Patient Health Questionnaire-9 (PHQ-9) was used assess by trained general practitioners (GPs), Mini International Neuropsychiatric...
Small mammals harbor a diverse array of zoonotic pathogens. To date, however, metagenomic surveys these species have primarily focused on viral diversity, with limited attention paid to bacteria and eukaryotic Additionally, the ecological determinants pathogen diversity within not been systematically examined. Herein, we employed metatranscriptomics approach survey infectome 2,408 individual samples, representing lung, liver, gut tissues from 858 animals collected throughout Guangdong...
Major depressive disorder (MDD) is the most prevalent mental health globally. However, association between symptom trajectories in early period and subsequent outcomes remains not fully elucidated. This study aimed to delineate during initial phase of treatment, identify baseline characteristics associated with these trajectories, explore quality life suicidal ideation. Participants were from Depression Cohort China. The diagnosis MDD was assessed using Mini-International Neuropsychiatric...
Suboptimal medication adherence is a major reason for failure in the management of depressive disorder (MDD), childhood trauma might be an essential risk factor suboptimal adherence. This study aimed to comprehensively explore associations between different types and among patients with MDD, test whether resilience has moderating effects on foregoing associations.Participants were from Depression Cohort China (ChiCTR registry number 1900022145), 282 MDD completed both baseline 12-weeks...
Background Depression is associated with significant morbidity and human capital costs globally. Early screening for depressive symptoms timely disorder case identification intervention may improve health outcomes cost-effectiveness among affected individuals. China’s public academic communities have reached a consensus on the need to access early screening, diagnosis, treatment of depression. Objective This study aims estimate prevalence factors subthreshold Chinese residents enrolled in...
Many people living with major depressive disorder (MDD) in China do not receive treatment owing to a lack of mental health services, along significant stigma toward illness. Internet-based cognitive behavioral therapy (ICBT) has been proposed increase access care for MDD.The aims this study were (1) evaluate the efficacy ICBT symptoms patients MDD; (2) effect on anxiety symptoms, nonspecific psychological distress, general self-efficacy, depression stigma, social function, and health-related...
This study sought to assess the differences in mental health conditions among general population, quarantined population and healthcare workers during COVID-19 outbreak China. An online rapid assessment captured depressive anxiety symptoms, sleep quality data. A total of 2689 participants (n=374 n=403 workers, n=1912 population) were included final statistical analysis. The proportion individuals with mild and/or serious depression higher when compared (58.6% vs. 25.1%vs. 48.6%, P<0.001;...
Objective: Angiotensin II (AngII) type 1 receptor (AT1R) blockers have been proved to reduce atherosclerosis. Previously, we invented ATRQβ-001 vaccine which showed a desirable blocking effect for AT1R. The purpose of this study was investigate whether would prevent atherosclerosis in apolipoprotein E-null (ApoE–/–) mice. Methods: Male ApoE–/– mice were administered with vaccine, Qβ virus-like particles, valsartan or vehicle over period 24 weeks. In vitro, human coronary artery endothelial...
This large-scale study aimed to test, among Chinese adolescents, the association between problematic Internet use (PIU), non-medical of prescription drugs (NMUPD), and depressive symptoms, as well mediating effects NMUPD on associations above. used data from 2017 National School-based Adolescents Health Survey, 24,345 students' questionnaires qualified for analyses. Generalized linear mixed models path were performed. In without mediation, PIU was associated with symptoms (unstandardized β...
Genome-wide association studies (GWASs) have identified risk loci for suicide attempt (SA), but deciphering how they confer SA remains largely unknown. This study aims to identify the key proteins and gain insights into pathogenesis. We integrated data from brain proteome (N = 376) blood 35,559) combined it with largest GWAS summary statistics date 518,612). A comprehensive set of methods was employed, including Mendelian randomization (MR), Steiger filtering, Bayesian colocalization,...
To assess the effectiveness of a 6-month Ba Duan Jin exercise program in improving balance community-dwelling older adults.