A5112473908- Pregnancy and preeclampsia studies
- Traditional Chinese Medicine Studies
- Medical Research and Treatments
- Chinese history and philosophy
- Gestational Diabetes Research and Management
- Endometrial and Cervical Cancer Treatments
- Neurological Disease Mechanisms and Treatments
- Traditional Chinese Medicine Analysis
- Birth, Development, and Health
- Orthopedic Infections and Treatments
- Magnetism in coordination complexes
- Assisted Reproductive Technology and Twin Pregnancy
- Acute Ischemic Stroke Management
- Healthcare and Venom Research
- Cytomegalovirus and herpesvirus research
- Organic and Molecular Conductors Research
- Pregnancy-related medical research
- Cervical Cancer and HPV Research
- Drug Transport and Resistance Mechanisms
- Metal complexes synthesis and properties
- Orthopaedic implants and arthroplasty
- China's Ethnic Minorities and Relations
- Medicinal Plants and Bioactive Compounds
- Cell Adhesion Molecules Research
- Lung Cancer Treatments and Mutations
Jiading District Central Hospital
2025
Shanghai University of Medicine and Health Sciences
2020-2025
Shanghai Skin Disease Hospital
2024-2025
Tongji University
2024-2025
Anhui Agricultural University
2025
Southwest Hospital
2025
Sichuan Cancer Hospital
2025
University of Electronic Science and Technology of China
2025
Chang Gung Memorial Hospital
2025
Chang Gung University
2025
The prevalecne of hyperuricemia in polycystic ovary syndrome (PCOS) is still uncertain. We aimed to investigate the prevalence PCOS and determine influence reproductive hormones on uric acid concentration.This retrospective cross-sectional study was performed at a large medicine center. Between March 2007 October 2016, total 1,183 women with 10,772 without were included. diagnosed according Rotterdam criteria. Anthropometric parameters, blood pressure, acid, hormones, glucose lipids measured...
To investigate the effect of transverse tibial bone transport on treatment Wagner Stage 4 diabetic foot.From January 2017 to October 2019, a total 19 patients with foot ulcers were recruited. All treated transport. A detailed follow-up was carried out at 1 week, month, 3 months, 6 and year after surgery. The wound healing rate limb salvage surgery evaluated. Preoperative 3-month postoperative digital subtraction angiography (DSA) obtained. level vascular endothelial growth factor (VEGF),...
Rationale: The antitumor activity of high-dose ascorbate has been re-evaluated recently, but the mechanism underlying cell-specific sensitivity to not yet clarified. Methods: effects on gastric cancer were assessed using cell lines with high and low expression GLUT1 via flow cytometry colony formation assays in vitro patient-derived xenografts vivo. Results: In this study, we demonstrated that cells more sensitive treatment than expression. knockdown significantly reversed therapeutic...
Mesenchymal stem cells (MSCs) are considered to be an ideal source for the cell therapy of end‑stage liver diseases. Umbilical cord (UC)‑MSCs can obtained via a non‑invasive procedure and easily cultured, making them potentially superior candidates transplantation when compared with MSCs from other sources. In present study, UC‑MSCs were induced differentiate into hepatocytes bone marrow (BM)‑MSCs their hepatic differentiation potential. showed significantly higher proliferation than...
Abstract Background Accurate preoperative planning is an important step for accurate reconstruction in total hip arthroplasty (THA). Presently, completed using either a two-dimensional (2D) template or three-dimensional (3D) mimics software. With the development of artificial intelligence (AI) technology, AI HIP, software based on can quickly and automatically identify acetabular femur morphology, match optimal prosthesis size. However, accuracy feasibility its clinical application still...
In emergency warning nursing, the pre-alert system significantly influences biochemical markers and clinical outcomes of patients with Acute Stress Disorder. Therefore, this study applies hierarchical analysis to explore impact early nursing on crucial indicators such as C-reactive protein (CRP), procalcitonin (PCT), tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), assess their efficacy. The selected acute stress disorder who were hospitalized in Southwest Hospital Chongqing from...
Objective: Colorectal Cancer (CRC) has attracted much attention due to its high mortality and morbidity. Cordycepin, also known as 3'-deoxyadenosine (3'-dA), exhibits many biological functions, including antibacterial, anti-inflammatory, antiviral, anti-tumor, immunomodulatory effects. It been proven show anticancer activity in both laboratory research studies living organisms. However, the molecular mechanism of effect cordycepin on CRC remains unclear. Methods: The genes associated with...
Abstract Background Oily skin not only threatens people with aesthetic and hygienic discomfort but also confronts them annoying problems. To explore new care ingredients from herbal or plant extracts understand their underlying mechanism for sebum control would assist in the discovery of desirable sebosuppressive agents, though it is still a deserving challenging task. Aim effect Camellia saponin (CS) on modulating lipogenesis human sebocytes. Moreover, to CS oleic acid/linoleic acid (OL)...
[Ru(II)(hedta)L](n)()(-) complexes (hedta(3)(-) = N-(hydroxyethyl)ethylenediaminetriacetate; L NO(+), n 0; NO, 1; NO(-), 2) have been prepared by the displacement of H(2)O/D(2)O via NO(g) or NO(2)(-). This is first reported entire set and NO(-) as ligands for same metal center in a constant oxidation state with ligand environment (here Ru(II) amino carboxylate hedta(3)(-)). From NO stretching frequencies isolated salts, net influence back-donation its sigma-withdrawal was observed to be that...
A number of miRNAs associated with wound repair have been identified and characterized, but the mechanism has not fully clarified. MiR-21 is one wound-related lncRNAs, study aimed to explore functional involvement miR-21 its concrete in healing. In this study, rat model skin wounds was established. The expression miR-21, PTEN related molecules tissues or cells determined by quantitative real-time PCR Western blot, respectively. regulatory role on examined luciferase reporter gene assay. Flow...
Acute kidney injury occurs frequently in COVID-19 patients infected by the coronavirus SARS-CoV-2, and infection of cells this virus has been reported. However, little is known about direct impact SARS-CoV-2 upon renal tubular cells. We report that activated signal transducer activator transcription 3 (STAT3) signaling caused cellular human cell line. Mechanistically, viral protein ORF3A augmented both NF-κB STAT3 increased expression molecule 1. or alone elevated level tripartite...
Autophagy and apoptosis are two recognized mechanisms of resistance to bacterial invasion. However, bacteria have likewise evolved the ability evade immunity. In this study, we identify ACKR4a, a member an atypical chemokine receptor family, as suppressor NF-κB pathway, which cooperates with Beclin-1 induce autophagy inhibit signaling block apoptosis, facilitating Vibrio harveyi infection. Mechanistically, V. harveyi-induced Ap-1 activates ACKR4a transcription expression. forms complex...
Background Preeclampsia/eclampsia is a severe pregnancy-related disorder associated with hypertension and organ damage. While observational studies have suggested link between maternal iron status preeclampsia/eclampsia, the causal relationship remains unclear. The aim of this study was to investigate genetic causality preeclampsia/eclampsia using large-scale genome-wide association (GWAS) summary data Mendelian randomization (MR) analysis.
Acute liver injury is a life-threatening syndrome that often caused by hepatocyte damage and characterized inflammatory oxidative responses. Helenalin isolated from Centipeda minima (HCM) has been found to have anti-inflammatory anti-oxidative effects. Here, this study aimed investigate the effects underlying mechanisms of HCM on Lipopolysaccharide/D-Galactosamine (LPS/D-GalN)-induced acute injury. Mice were intragastrically administered with various dose for 10 days; 2 h after final...
Abstract Background Eukaryotic translation initiation factor 6 (eIF6) has a crucial function in the maturation of 60S ribosomal subunits, and it controls protein translation. Although emerging studies indicate that eIF6 is aberrantly expressed various types cancers, functions underlying molecular mechanisms pathological progression hepatocellular carcinoma (HCC) remain unclear. This study aimed to evaluate potential diagnostic prognostic value patients with HCC. Methods HCC samples enrolled...