A5101835627- Mathematical and Theoretical Epidemiology and Ecology Models
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Gastric Cancer Management and Outcomes
- Phytochemistry and Biological Activities
- Natural product bioactivities and synthesis
- Colorectal Cancer Screening and Detection
- RNA modifications and cancer
- Phytochemical compounds biological activities
- Advanced Differential Equations and Dynamical Systems
- Plant Gene Expression Analysis
- Gut microbiota and health
- Quantum chaos and dynamical systems
- COVID-19 epidemiological studies
- Advanced Sensor and Control Systems
- Liver Disease Diagnosis and Treatment
- Plant biochemistry and biosynthesis
- Plant-derived Lignans Synthesis and Bioactivity
- Esophageal Cancer Research and Treatment
- Gastrointestinal disorders and treatments
- Traditional and Medicinal Uses of Annonaceae
- Esophageal and GI Pathology
- Cancer-related gene regulation
- Endometrial and Cervical Cancer Treatments
Aerospace Center Hospital
2021-2025
Soochow University
2015-2025
Second Affiliated Hospital of Soochow University
2025
China Medical University
2010-2024
Second Hospital of Shandong University
2016-2024
Beihua University
2012-2024
Beijing Shijingshan Hospital
2024
First Affiliated Hospital of Zhengzhou University
2008-2024
Jilin University
2003-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2017-2024
Objective The effect of colonoscopy on colorectal cancer mortality is limited by several factors, among them a certain miss rate, leading to adenoma detection rates (ADRs). We investigated the an automatic polyp system based deep learning rate and ADR. Design In open, non-blinded trial, consecutive patients were prospectively randomised undergo diagnostic with or without assistance real-time providing simultaneous visual notice sound alarm detection. primary outcome was Results Of 1058...
The autonomous vehicle is a mobile robot integrating multi-sensor navigation and positioning, intelligent decision making control technology. This paper presents the system architecture of vehicle, called “Intelligent Pioneer”, path tracking stability motion to effectively navigate in unknown environments discussed. In this approach, two degree-of-freedom dynamic model developed formulate path-tracking problem state space format. For controlling instantaneous error, traditional controllers...
Recent studies demonstrate that the human microbiota, collection of microorganisms growing on and in individuals, have numerous bidirectional interactions with host, influencing immunity, resistance to infection, inflammation metabolism. Little has been done study potential associations between microbiota composition transplant outcome. Here, we investigated longitudinal changes blood, urinary, oral rectal renal allograft recipients before at 1 6 months after transplantation. The results...
Disturbed balance between microbiota, epithelial cells, and resident immune cells within the intestine contributes to inflammatory bowel disease (IBD) pathogenesis. The Citrobacter rodentium-induced colitis mouse model has been well documented. This allows analysis of host responses enteric bacteria facilitates improved understanding potential mechanisms IBD current study evaluated effects dietary 30 mg/kg quercetin supplementation on C. experimental in C57BL/6 mice. Following...
Mucormycosis is a highly lethal fungal infection especially in immunocompromised individuals.
BACKGROUND The aim of this study was to examine the effects natural flavonoid, quercetin, in a rat model adenine-induced chronic kidney disease. MATERIAL AND METHODS Forty male Wister rats were divided into four groups: normal (no adenine or quercetin) (n=10); untreated (treated withadenine but not quercetin-treated (5 mg/kg/day for 21 days) (10 (n=10). Urine and blood samples collected kidneys examined histologically. RESULTS Comparison findings treated with quercetin (n=20) non-treated...
Colorectal cancer (CRC) is the fourth leading cause of tumor-related deaths worldwide. In this study, we explored in vivo effects quercetin, a plant flavonol from flavonoid group polyphenols with antioxidant effects, on colon carcinogenesis induced by azoxymethane/dextran sodium sulfate (AOM/DSS). Thirty mice were randomly assigned into three groups: control group, AOM/DSS and quercetin+AOM/DSS group. CRC was AOM injection solution 2% DSS drinking water. AOM/DSS-induced model, quercetin...
Accumulating evidence indicates that long non-coding RNAs (lncRNAs) play a crucial role in tumorigenesis. Here, we report novel lncRNA, RP11-436H11.5, regulates renal cell carcinoma (RCC) proliferation and invasion by sponging miR-335-5p. Expression of lncRNA RP11-436H11.5 was determined qRT-PCR assay RCC tissues. were measured transwell assay. BCL-W detected western blot Interactions between miR-335-5p luciferase reporter RNA-pull down In vivo experiments used to detect tumor formation....
Ultraviolet-B (UV-B) promotes anthocyanin accumulation and improves fruit quality in plants. To explore the underlying network of MYB transcription factors that regulates UV-B-induced biosynthesis blueberry (Vaccinium corymbosum), we analyzed response factor genes to UV-B treatment. Transcriptome sequencing analysis revealed VcMYBA2 VcMYB114 expression were upregulated positively correlated with structural under radiation according weighted gene co-expression (WGCNA) data. The...
Abstract Pressure ulcers are persistent skin lesions that have substantial detrimental effects on the physical well‐being of patients. Moreover, their psychological ramifications for both patients and caregivers becoming more widely acknowledged. This research was conducted to examine pressure ascertain efficacious approaches mitigate these improve overall well‐being. A cross‐sectional study from March 2022 December 2023 across tertiary care centres located in Beijing. The cohort consisted...
The aim of this study is to compare the effects propofol and sevoflurane anesthesia on perioperative immune response in patients undergoing laparoscopic radical hysterectomy for cervical cancer. Sixty with cancer scheduled elective under general were randomized into 2 groups. TIVA group received induction maintenance SEVO maintenance. Blood samples collected at 30 min before (T0); end operation (T1); 24 h (T2), 48 (T3), 72 (T4) after operation. T lymphocyte subsets (including CD3+ cells,...
Mesenchymal stem cells (MSCs) are considered to be an ideal source for the cell therapy of end‑stage liver diseases. Umbilical cord (UC)‑MSCs can obtained via a non‑invasive procedure and easily cultured, making them potentially superior candidates transplantation when compared with MSCs from other sources. In present study, UC‑MSCs were induced differentiate into hepatocytes bone marrow (BM)‑MSCs their hepatic differentiation potential. showed significantly higher proliferation than...
Background: Vitamin D (VD) and gut microbiota (GM) are important variables in pediatric hematopoietic stem cell transplantation (HSCT) recipients with bloodstream infections (BSI). Both VD GM play significant roles immune regulation maintaining intestinal barrier function. Methods: This prospective case-control study included 48 consecutive patients who underwent HSCT, as well 20 healthy children from the community. Plasma samples were collected pre- post-HSCT, together post-HSCT fecal...