A5077388232- Advanced MRI Techniques and Applications
- Functional Brain Connectivity Studies
- Advanced Neuroimaging Techniques and Applications
- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Cerebrovascular and Carotid Artery Diseases
- Acute Ischemic Stroke Management
- Advanced Radiotherapy Techniques
- Dementia and Cognitive Impairment Research
- Glioma Diagnosis and Treatment
- MRI in cancer diagnosis
- Epilepsy research and treatment
- Lung Cancer Diagnosis and Treatment
- Alzheimer's disease research and treatments
- Seed Germination and Physiology
- Cardiac Imaging and Diagnostics
- Wheat and Barley Genetics and Pathology
- Neurological disorders and treatments
- Neural dynamics and brain function
- EEG and Brain-Computer Interfaces
- Cardiovascular Health and Disease Prevention
- Traumatic Brain Injury and Neurovascular Disturbances
- Genetics and Plant Breeding
- Parkinson's Disease Mechanisms and Treatments
- Neuroscience and Neuropharmacology Research
Ministry of Agriculture and Rural Affairs
2018-2025
Capital Medical University
2016-2025
Anhui Agricultural University
2016-2025
Chinese Academy of Fishery Sciences
2016-2025
Third Hospital of Hebei Medical University
2025
Hebei Medical University
2025
Ministry of Education of the People's Republic of China
2023-2025
China Medical University
2023-2025
Fourth Affiliated Hospital of China Medical University
2023-2025
Beijing Geriatric Hospital
2025
Abstract We used resting‐state functional MRI to investigate spatial patterns of spontaneous brain activity in 22 healthy elderly subjects, as well 16 mild cognitive impairment (MCI) and Alzheimer's disease (AD) patients. The pattern intrinsic was measured by examining the amplitude low‐frequency fluctuations (ALFF) blood oxygen level dependent signal during rest. There were widespread ALFF differences among three groups throughout frontal, temporal, parietal cortices. Both AD MCI patients...
Prior randomized trials have generally shown harm or no benefit of stenting added to medical therapy for patients with symptomatic severe intracranial atherosclerotic stenosis, but it remains uncertain as whether refined patient selection and more experienced surgeons might result in improved outcomes.To compare plus vs alone stenosis.Multicenter, open-label, randomized, outcome assessor-blinded trial conducted at 8 centers China. A total 380 transient ischemic attack nondisabling,...
Oxidative stress from reactive oxygen species (ROS) is a reperfusion injury factor that can lead to cell damage and death. Here, ultrasmall iron-gallic acid coordination polymer nanodots (Fe-GA CPNs) were developed as antioxidative neuroprotectors for ischemia stroke therapy guided by PET/MR imaging. As proven the electron spin resonance spectrum, Fe-GA CPNs with size, scavenged ROS efficiently. In vitro experiments revealed could protect viability after being treated hydrogen peroxide (H
Background Studies have rarely investigated stenosis detection from head and neck CT angiography scans because accurate interpretation is time consuming labor intensive. Purpose To develop an automated convolutional neural network–based method for plaque classification in images compare its performance with that of radiologists. Materials Methods A deep learning (DL) algorithm was constructed trained use were collected retrospectively four tertiary hospitals between March 2020 July 2021....
Background: Alzheimer's disease (AD) is a common neurodegenerative in which the brain undergoes alterations for decades before symptoms become obvious. Subjective cognitive decline (SCD) have self-complain of persistent function especially memory but perform normally on standard neuropsychological tests. SCD with presence AD pathology transitional stage 2 continuum, earlier than prodromal stage, mild impairment (MCI), seems to be best target research AD. In this study, we aimed detect...
Several studies have found that inappropriate workstations are associated with musculoskeletal disorders. The present cross-sectional study aimed to identify the risk factors of non-specific neck pain (NP) and low back (LBP) among computer-using workers.Observational a sample.This surveyed 15 companies in Zhejiang province, China.After excluding participants missing variables, 417 office workers, including 163 men 254 women, were analyzed.Demographic information was collected by self-report....
Intrinsic functional connectivity detected by MRI (fMRI) provides a useful but indirect approach to study the organization of human brain systems. An unresolved question is whether measured resting-state fMRI reflects anatomical connections. In this study, we used well-characterized anatomy cerebrocerebellar circuits directly test intrinsic associated with an anatomic pathway. Eleven first-episode stroke patients were scanned five times during period 6 months, and 11 healthy control subjects...
Virus infection of plants may induce a variety disease symptoms. However, little is known about the molecular mechanism systemic symptom development in infected plants. Here we performed first next-generation sequencing study to identify gene expression changes associated with tobacco (Nicotiana tabacum cv. Xanthi nc) induced by M strain Cucumber mosaic virus (M-CMV). Analysis transcriptome RNA-Seq identified 95,916 unigenes, 34,408 which were new transcripts database searches. Deep was...
The present study aimed to investigate changes in structural gray matter (GM) volume and functional amplitude of spontaneous low-frequency oscillations (LFO) connectivity density patients with subcortical vascular mild cognitive impairment (svMCI). Structural MRI resting-sate data were collected from 26 svMCI 28 age- gender-matched healthy controls. Structurally, widespread GM atrophy was found the that resided primarily frontal (e.g., superior middle gyri medial prefrontal cortex) temporal...
Functional MRI (fMRI) studies have traditionally relied on intersubject normalization based global brain morphology, which cannot establish proper functional correspondence between subjects due to substantial variability in organization. Here, we reliably identified a set of discrete, homologous regions individuals improve alignment fMRI data. These demonstrated marked size, position, and connectivity. We found that previously reported connectivity maps could be partially explained by size...
The computed tomography angiography (CTA) postprocessing manually recognized by technologists is extremely labor intensive and error prone. We propose an artificial intelligence reconstruction system supported optimized physiological anatomical-based 3D convolutional neural network that can automatically achieve CTA in healthcare services. This trained tested with 18,766 head neck scans from 5 tertiary hospitals China collected between June 2017 November 2018. overall accuracy of the...
Hippocampal morphological change is one of the main hallmarks Alzheimer's disease (AD). However, whether hippocampal radiomic features are robust as predictors progression from mild cognitive impairment (MCI) to AD dementia and these provide any neurobiological foundation remains unclear. The primary aim this study was verify can serve magnetic resonance imaging (MRI) markers for AD. Multivariate classifier-based support vector machine (SVM) analysis provided individual-level predictions...
Abstract Purpose Glioma treatment planning requires precise tumor delineation, which is typically performed with contrast-enhanced (CE) MRI. However, CE MRI fails to reflect the entire extent of glioma. O-(2- 18 F-fluoroethyl)-L-tyrosine ( F-FET) PET may detect volumes missed by We investigated clinical value simultaneous FET-PET and in delineating before planning. Guided stereotactic biopsy was used validate findings. Methods Conventional F-FET were simultaneously on a hybrid PET/MR 33...
Electronic skin (e-skin) is attracting huge attention due to its promising applications in diverse fields, including biomimetic machines, artificial intelligence and smart robotics.
Abstract Precision medicine for Alzheimer's disease (AD) necessitates the development of personalized, reproducible, and neuroscientifically interpretable biomarkers, yet despite remarkable advances, few such biomarkers are available. Also, a comprehensive evaluation neurobiological basis generalizability end‐to‐end machine learning system should be given highest priority. For this reason, deep model (3D attention network, 3DAN) that can simultaneously capture candidate imaging with an...
Significance Strawberry is a very popular fruit. The strawberry genus ( Fragaria ) has emerged as model system for various fundamental and applied research in recent years. Here, by using high-throughput sequencing technologies, we provide de novo whole-genome sequences five wild species genome resequencing data 128 additional accessions of key species. Our analyses resulted robust estimates the evolutionary history most diploid species, discovery new emeiensis Jia J. Lei), construction...
Some cheap and easily used operated indexes of insulin resistance (IR) were currently available. We aimed to evaluate the association six surrogate IR with incident stroke compare their predictive capacity.We analysed data from 14,595 eligible study participants Rural Chinese Cohort Study. Modified Poisson regression models estimate relative risks (RRs) 95% confidence intervals (95% CIs) associated visceral adiposity index (VAI), (CVAI), lipid accumulation product (LAP), triglyceride-glucose...
Abnormal activation of immune system is an important pathogenesis Parkinson's disease, but the relationship between peripheral inflammation, central microglia and dopaminergic degeneration remains unclear.To evaluate brain regional its with clinical severity, presynaptic function, inflammatory biomarkers related to adaptive immunity.In this case-control study, we recruited 23 healthy participants 24 early-stage disease. 18F-PBR06 PET/MR for activation, 18F-FP-DTBZ denervation, total account...
To investigate the perspectives and expectations of faculty radiologists, residents, medical students regarding integration artificial intelligence (AI) in radiology education, a survey was conducted to collect their opinions attitudes on implementing AI education. An online questionnaire used for this survey, participant anonymity ensured. In total, 41 38 120 from authors' institution completed questionnaire. Most residents experience different levels psychological stress during initial...