A5090176604- Intracranial Aneurysms: Treatment and Complications
- Cerebrovascular and Carotid Artery Diseases
- Vascular Malformations Diagnosis and Treatment
- Acute Ischemic Stroke Management
- Radio Wave Propagation Studies
- Neurological Disease Mechanisms and Treatments
- Moyamoya disease diagnosis and treatment
- Intracerebral and Subarachnoid Hemorrhage Research
- Glioma Diagnosis and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Neuroscience and Neuropharmacology Research
- Cardiovascular Health and Disease Prevention
- Advanced Battery Technologies Research
- Simulation and Modeling Applications
- Head and Neck Surgical Oncology
- Precipitation Measurement and Analysis
- Neurosurgical Procedures and Complications
- Traditional Chinese Medicine Analysis
- Geophysics and Gravity Measurements
- CO2 Reduction Techniques and Catalysts
- Inertial Sensor and Navigation
- Seismic and Structural Analysis of Tall Buildings
- Kidney Stones and Urolithiasis Treatments
- Advanced Algorithms and Applications
- GNSS positioning and interference
Air Force Medical University
2014-2025
Tianjin University
2023-2025
Shenzhen Bao'an District People's Hospital
2009-2025
Nanjing Agricultural University
2024
Collaborative Innovation Center of Chemical Science and Engineering Tianjin
2023-2024
Blind and Sight Impaired Society
2024
Tang Du Hospital
2006-2022
The Second Affiliated Hospital of Xiamen Medical College
2022
Qingdao University of Technology
2022
Hengshui University
2021
Prior randomized trials have generally shown harm or no benefit of stenting added to medical therapy for patients with symptomatic severe intracranial atherosclerotic stenosis, but it remains uncertain as whether refined patient selection and more experienced surgeons might result in improved outcomes.To compare plus vs alone stenosis.Multicenter, open-label, randomized, outcome assessor-blinded trial conducted at 8 centers China. A total 380 transient ischemic attack nondisabling,...
Previous randomized clinical trials did not demonstrate the superiority of endovascular stenting over aggressive medical management for patients with symptomatic intracranial atherosclerotic stenosis (sICAS). However, balloon angioplasty has been investigated in a trial.
Stroke has been the leading cause of adult morbidity and mortality over past several years. After an ischemic stroke attack, many dormant or reversibly injured brain cells exist in penumbra area. However, pathological processes unique cell information area acute remain elusive. We applied unbiased single sequencing combination with bulk RNA-seq analysis to investigate heterogeneity each type early stages detect possible therapeutic targets help survival. used these analyses study mouse...
<h3>BACKGROUND AND PURPOSE:</h3> On the basis of high 1-month stroke and/or death (14.7%) rates associated with stent placement in Stenting versus Aggressive Medical Management for Preventing Recurrent Stroke Intracranial Stenosis trial, modifications patient selection and procedural aspects intracranial have been recommended. We performed a multicenter prospective single-arm trial to determine whether such would result lower periprocedural death. <h3>MATERIALS METHODS:</h3> The study...
Background Patients with symptomatic stenosis of intradural arteries are at high risk for subsequent stroke. Since the SAMMPRIS trial, stenting is no longer recommended as primary treatment; however, results this its inclusion criteria and center selection received significant criticism did not appear to reflect our experience regarding natural history nor treatment complications rate. As intracranial atherosclerosis (ICAS) most common cause stroke in Asian countries, we hereby proposing a...
CD24 is overexpressed in glioma cells <i >in vitro</i> and vivo</i>. However, the correlation of its expression with clinicopathological parameters gliomas prognostic significance this tumor remain largely unknown. To address problem, 151 specimens 10 nonneoplastic brain tissues were collected. Quantitative real-time PCR, immunochemistry assay, Western blot analysis carried out to investigate CD24. As per results, was gliomas. Its levels higher grade (<svg...
Abstract Objectives Notch signaling plays a complex role in human malignancy. It can affect cell proliferation, differentiation, and apoptosis either positively or negatively, depending on type. Methods Clinical gliomas from 274 patients who had not received chemotherapy were collected, the expression of Notch1 protein was assessed by immunochemistry assays. Staining evaluation results analyzed statistically relation to various clinicopathological characters. Kaplan–Meier Cox proportional...
Currently, there is no established treatment consensus for craniocervical unruptured dissecting aneurysms (UDAs). This study aimed to assess the safety and efficacy of Surpass Streamline Flow Diverter (SSFD) treating UDAs.
The study aims to compare the efficacy of flexible ureteroscopy (FURS) with holmium laser lithotripsy (HLL, herein collectively referred as FURS-HLL) and percutaneous nephrolithotomy (PCNL) in treatment complex upper urinary tract calculi elderly patients, highlighting advantages FURS-HLL. A total 40 patients (aged ≥ 60) admitted Department Urology, Fuyong People's Hospital from October 2020 2023 were randomly divided into 2 groups on basis they received: FURS-HLL group (preset ureteral...
Objective Blood urea nitrogen (BUN) is a commonly used biomarker for assessing kidney function and neuroendocrine activity. Previous studies have indicated that elevated BUN levels are associated with increased mortality in various critically ill patient populations. The focus of this study was to investigate the relationship between 28-day intensive care patients. Methods This multi-centre retrospective cohort made use data from eICU Collaborative Research Database. primary exposure...
BACKGROUND: Whether the long-term benefit of stroke prevention when stenting is added to medical therapy (MT) over MT alone for symptomatic severe intracranial artery stenosis offsets perioperative risks has not been directly evaluated in a randomized trial. We aimed compare (>3 years) effect versus patients with METHODS: extended follow-up 358 subjects enrolled multicenter, open-label, trial conducted at 8 centers China. Patients transient ischemic attack or attributed (70% 99%) were...
Basigin/CD147, also named extracelluar matrix metalloproteinase inducer (EMMPRIN), has been implicated in playing very important roles several aspects of tumor progression. In this study, we examined the inhibitory effects antisense RNA CD147 on invasion and angiogenesis human glioblastoma U251 cells vitro. The cell line was transfected by a plasmid containing cDNA. Gelatin zymography used to determine effect reducing secretions MMP-2 MMP-9 cells. Boyden chamber employed test We found that...
To examine the expression of SMAD4 at gene and protein levels in glioma samples with different WHO grades its association survival.Two hundreds fifty-two specimens 42 normal control tissues were collected. Immunochemistry assay, quantitative real-time PCR Western blot analysis carried out to investigate SMAD4. Kaplan-Meier method Cox's proportional hazards model used survival analysis.Immunohistochemistry showed that was decreased glioma. mRNA both lower compared on (both P < 0.001). In...
Background A recent trial failed to show any benefit of stenting plus medical therapy over alone in patients with symptomatic intracranial stenosis. We aimed examine whether the qualifying artery modifies effect therapy. Methods This is a post-hoc analysis CASSISS that included stenosis, randomly assigned undergo or alone; 358/380 were included. Multivariable logistic regression was used an interaction term estimate altered treatment by artery. The primary outcome composite stroke death...
Repeat gamma knife radiosurgery (GKRS) is considered to be an effective treatment for refractory or recurrent trigeminal neuralgia (TN).The purpose of this report was demonstrate the relationship between outcome repeat GKRS and prior operative procedures on patients with TN.A retrospective analysis performed 34 TN who had undergone GKRS; 21 other types procedures, 11 whom more than three such radiosurgery. The maximum dose procedure 60 75 Gy. mean follow-up time 21.6 months.The log-rank test...
The aberrant expression of regenerating islet-derived family member, 4 (Reg IV) has been found in various human cancers. However, the roles Reg IV gene and its encoding product glioma have not clearly understood. Therefore, aim this study was to investigate clinicopathological significance glioma.Reg mRNA protein gliomas non-neoplastic brain tissues were respectively detected by real-time quantitative RT-PCR assay, Western blot, immunohistochemistry. association immunostaining with factors...