- Electrospun Nanofibers in Biomedical Applications
- RNA modifications and cancer
- Hepatocellular Carcinoma Treatment and Prognosis
- Pancreatic and Hepatic Oncology Research
- RNA Research and Splicing
- Tissue Engineering and Regenerative Medicine
- Cancer-related molecular mechanisms research
- Extracellular vesicles in disease
- Radiomics and Machine Learning in Medical Imaging
Henan Provincial People's Hospital
2022-2024
Beijing Radiation Center
2024
Zhengzhou University
2022
Abstract Radiotherapy is essential for treating colorectal cancer (CRC), especially in advanced rectal cancer. However, the low radiosensitivity of CRC cells greatly limits radiotherapy efficacy. Small nucleolar RNAs (snoRNAs) are a class noncoding RNA that primarily direct post‐transcriptional modifications ribosomal (rRNAs), small nuclear (snRNAs), and other cellular RNAs. While snoRNAs involved tumor progression chemoresistance, their association with remains largely unknown. Herein,...
Objectives To investigate the ability of ultrasomics to predict Ki‐67 expression in hepatocellular carcinoma (HCC). Methods A total 244 patients from three hospitals were retrospectively recruited (training dataset, n = 168; test 43; and validation 33). Lesion segmentation ultrasound images was performed manually by two radiologists. In total, 1409 features extracted. Feature selection conducted using intra‐class correlation coefficient, variance threshold, mutual information, recursive...