Ayşegül Danış

ORCID: 0000-0003-0962-2116
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About
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Research Areas
  • Epilepsy research and treatment
  • Nerve Injury and Rehabilitation
  • Neonatal and fetal brain pathology
  • Pharmacological Effects and Toxicity Studies
  • Migraine and Headache Studies
  • Bacterial Infections and Vaccines
  • Shoulder and Clavicle Injuries
  • Neuroscience and Neuropharmacology Research
  • Spinal Fractures and Fixation Techniques
  • Histiocytic Disorders and Treatments
  • Infectious Encephalopathies and Encephalitis
  • Vitamin D Research Studies
  • Cerebral Palsy and Movement Disorders
  • Infant Development and Preterm Care
  • Child Nutrition and Feeding Issues
  • Anesthesia and Sedative Agents
  • Shoulder Injury and Treatment
  • Genomics and Rare Diseases
  • Spine and Intervertebral Disc Pathology
  • Medical and Biological Sciences
  • Drug-Induced Hepatotoxicity and Protection
  • Electrospun Nanofibers in Biomedical Applications
  • Hedgehog Signaling Pathway Studies
  • Methemoglobinemia and Tumor Lysis Syndrome
  • Nosocomial Infections in ICU

Bolu Abant İzzet Baysal University
2020-2025

Pediatrics and Genetics
2022

Sağlık Bilimleri Üniversitesi
2020-2021

Dr Sami Ulus Çocuk Sağlığı ve Hastalıkları Eğitim ve Araştırma Hastanesi
2017-2020

Ministry of Health
2020

The purpose of this study was to investigate the serum levels mitochondrial metabolism/reactive oxygen species (ROS)-related peptides (hypoxia inducible factor-1α [HIF-1α], fibroblast growth factor-21 [FGF-21], differentiation factor-15 [GDF-15]) and key migraine-related neuropeptides (calcitonin gene-related peptide [CGRP], pituitary adenylate cyclase-activating peptide-38 [PACAP-38], substance P [SP], vasoactive intestinal [VIP]) during migraine attacks evaluate their diagnostic value in...

10.1111/head.14618 article EN cc-by-nc-nd Headache The Journal of Head and Face Pain 2023-08-19

Abstract The purpose of this study was to enhance understanding CACNA1A gene variants by elucidating the clinical profiles patients with different variants. overlapping features and varying phenotypic characteristics these neurological disorders pose challenges for clinicians. A data collection form utilized gather features, examination details, treatment information associated Thirty-one were included in from 11 clinics Turkey. Cases assessed comparing their existing literature. initially...

10.1007/s00431-025-06062-3 article EN cc-by European Journal of Pediatrics 2025-03-20

Acute necrotizing encephalopathy is a rare type of acute characterized by multi-ocal brain lesions and associated severe neurological findings various organ dysfunctions may accompany it.Patients with childhood diagnosed pediatric neurology intensive care at Sami Ulus Maternity, Child Health Diseases Training Research Hospital between 2007 2020 were included in this study.Nine patients (six females, three males) mean age 4.05 ± 1.94 years (age range 1–6.5) study. The interval fever was 1–4...

10.3906/sag-2102-47 article EN TURKISH JOURNAL OF MEDICAL SCIENCES 2021-03-22

Aim: Type 1 diabetes which is a chronic metabolic disease can affect the quality of life person. The aim this study to evaluate diabetic children and adolescents who are diagnosed with type mellitus compare perceptions through scale before after summer camp. Materials Method: A was applied 31 children/adolescents Diabetes Mellitus between ages 9-16 years in Summer Camp. Results: perceived / were better camp (p< 0.05). When Quality Life Scale scores compared by gender, it found that...

10.5455/jtomc.2017.04.061 article EN Journal of Turgut Ozal Medical Center 2017-01-01

Aim: Perinatal asphyxia affects whole body systems and depending on compensation mechanisms, the central nervous system is primarily protected. In this study, we aimed to evaluate brain electrophysiological activity in cases with postnatal feeding intolerance due perinatal investigate whether mechanism adequate or there a minimal disorder. Methods: This study was conducted prospectively compare amplitude electroencephalography (EEG) recordings of 22 patients who were followed up diagnosis 10...

10.54307/2024.nwmj.135 article EN cc-by Northwestern Medical Journal 2024-07-12

Purpose: This study aimed to identify the predictors of gross motor function in spastic-type Cerebral Palsy (CP) over two years. Methods: 108 children with CP (mean age: 6.43±4.83 years) underwent assessments The outcomes were Gross Motor Function Classification System (GMFCS), Manual Ability (MACS), Communication (CFCS), and Eating Drinking (EDACS). Binary logistic regression analysis was used determine whether factors such as age, sex, topographical distribution, levels GMFCS, MACS, CFCS,...

10.21653/tjpr.1443503 article EN Türk fizyoterapi ve rehabilitasyon dergisi 2024-06-20

Abstract&#x0D; Objective: In this study, it was aimed to analyze the demographic characteristics, mortality rates, hospitalization rates and causes of trauma in pediatric patients admitted emergency department with head trauma.&#x0D; Materials Methods: Pediatric a university hospital (tertiary service) between 01.01.2015 31.12.2020 due were included study. Demographic data patients, computed tomography reports heads, inpatient departments or intensive care units, discharge status, Glasgow...

10.47493/abantmedj.1284334 article EN Bolu Abant Izzet Baysal Universitesi Tip Fakultesi Abant Tip Dergisi 2023-05-24

The purpose of this study was to examine the protective and therapeutic effects okra (Abelmoschus esculentus [AE]) seed extract, with its known antioxidant, immunomodulatory, anti-inflammatory properties, in an acetaminophen (paracetamol, N-acetyl- para-aminophenol)-induced model hepatotoxicity subsequent acute non-traumatic brain damage.Forty male Wistar rats were randomly divided into five equal groups, control, paracetamol (P), extract (AE), + (P AE), N-acetyl cysteine (NAC) AE N)....

10.1080/00207454.2023.2292948 article EN International Journal of Neuroscience 2023-12-07

Mycoplasma pneumonia (M. pneumonia) is a common cause of respiratory tract illness in children (Waites & Talkington, Clinical Microbiology Reviews 2004; 17-4, 697–728). Central nervous system (CNS) complications are the most extrapulmonary manifestations M. infection. CNS involvement has been reported up to 7% patients hospitalized with (Bitnun et al., Pediatric Infectious Diseases, 2003; 14-2, 96–107; Koskiniemi, Diseases 1993; 17-1, 52–57; Pönkä, Scandinavian Journal 1980; 12-3, 175–184)....

10.1055/a-1138-0744 article EN Klinische Pädiatrie 2020-04-27

Aim: Epilepsy frequently accompanies neurocutaneous syndromes. Due to the comorbid conditions that epileptic seizures may cause, their frequency, type, and duration also affect prognosis of diseases. The purpose this study was examine frequency epilepsy drug-resistant in syndromes, factors affecting development epilepsy.Methods: In our clinic, nine 24 patients who were under follow-up due syndromes diagnosed with Tuberous Sclerosis Complex (TSC), six Sturge-Weber syndrome, Neurofibromatosis...

10.54307/nwmj.2023.77486 article EN cc-by Northwestern Medical Journal 2023-02-01

The purpose of this study was to evaluate the relationship between presence pneumonia and blood parameters in casesof Coronavirus disease (COVID-19) examine their predictive characteristics terms pneumonia. We reviewed filerecords 151 pediatric patients with a diagnosis COVID-19 confirmed by real time-reverse transcription polymerase chainreaction test nasopharyngeal swabs. were divided into two groups based on direct chest X-ray computedtomography results [Group 1 (n:41), findings, Group 2...

10.4274/jpea.2023.200 article EN cc-by-nc-nd The Journal of Pediatric Academy 2023-03-31

Neurological involvement is very rare in patients with a diagnosis of Langerhans Cell Histiocytosis (LCH). During the course disease, headache can also be seen addition to systemic effects. A 6 years old girl was admitted hospital only without any symptoms and diagnosed LCH. Magnetic resonance imaging showed solid mass extending from sphenoid bone corpus left great wing sphenoid, orbital apex, posterior ethmoid cells, cavernous sinus, dural space. The correct decision for neuroimaging...

10.21673/anadoluklin.1239361 article EN Anadolu Kliniği Tıp Bilimleri Dergisi 2023-04-02

Aim: We aimed to reveal the similarities and differences between rare severe multisystem inflammatory syndrome (MIS-C) active familial Mediterranean fever (FMF) disease in children. Our study may help early recognition of MIS-C children distinguish it from other diseases with similar symptoms.Methods: evaluated demographic clinical characteristics, laboratory findings, treatments outcomes patients FMF.Results: The findings a total 66 hospitalized our pediatric clinic diagnosis FMF (n: 42)...

10.54307/nwmj.2023.38039 article EN cc-by Northwestern Medical Journal 2023-06-01

Epilepsy is the most common childhood neurological disorder that affects 0.5 to 1.0 % of children younger than 16 years age. Cognitive and behavioral impairments as well various psychiatric neurodevelopmental disorders can accompany this condition. Among adolescents, occipital epilepsy be easily overlooked because it mimic other epileptic syndromes symptoms may subtle. The initial complaint a patient suffering from could visual hallucinations. Child adolescent psychiatrists must aware...

10.17826/cumj.1322493 article EN Çukurova medical journal (Online)/Çukurova medical journal 2023-12-28
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