A5001464501- Dementia and Cognitive Impairment Research
- Nutritional Studies and Diet
- Diet and metabolism studies
- Palliative Care and End-of-Life Issues
- Frailty in Older Adults
- Geriatric Care and Nursing Homes
- Patient-Provider Communication in Healthcare
- Stroke Rehabilitation and Recovery
- Technology Use by Older Adults
- Nutrition and Health in Aging
- Chronic Disease Management Strategies
- Healthcare Decision-Making and Restraints
- Psychiatric care and mental health services
- Interprofessional Education and Collaboration
- Cerebral Palsy and Movement Disorders
- Health disparities and outcomes
- Health, psychology, and well-being
- COVID-19 and Mental Health
- Intensive Care Unit Cognitive Disorders
- Neuroscience and Music Perception
- Nutrition, Genetics, and Disease
- Music Therapy and Health
- Long-Term Effects of COVID-19
- Aging and Gerontology Research
- Child Nutrition and Feeding Issues
Karolinska Institutet
2017-2024
Mälardalen University
2012-2024
Karolinska University Hospital
2021-2024
University of Gävle
2023-2024
Imperial College London
2022
University of Eastern Finland
2022
ORCID
2021
Örebro University
2012-2015
Abstract Background Combining multimodal lifestyle interventions and disease-modifying drugs (novel or repurposed) could provide novel precision approaches to prevent cognitive impairment. Metformin is a promising candidate in view of the well-established link between type 2 diabetes (T2D) Alzheimer’s Disease emerging evidence its potential neuro-protective effects (e.g. vascular, metabolic, anti-senescence). MET-FINGER aims test FINGER 2.0 intervention, combining an updated multidomain...
<h3>Background and Objectives</h3> ATN (β-amyloid [Aβ], tau, neurodegeneration) system categorizes individuals based on their core Alzheimer disease (AD) biomarkers. An important potential future use for is therapeutic decision-making in clinical practice once disease-modifying treatments (e.g., anti-amyloid), become widely available. In this cross-sectional study, we applied estimated eligibility anti-amyloid treatment a real-life memory clinic with biomarker assessments integrated into the...
The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) showed cognitive benefits from a multidomain lifestyle intervention in at-risk older people. LipiDiDiet trial highlighted of medical food prodromal Alzheimer's disease (AD). However, the feasibility impact multimodal interventions combining with AD is unclear. MIND-ADmini was 6-month multinational (Sweden, Finland, Germany, France) proof-of-concept randomized controlled (RCT). Participants were...
Background: Interventions simultaneously targeting multiple risk factors and mechanisms are most likely to be effective in preventing cognitive impairment. This was indicated the Finnish Geriatric Intervention Study Prevent Cognitive Impairment Disability (FINGER) testing a multidomain lifestyle intervention among at-risk individuals. The importance of medical food at early symptomatic disease stage, prodromal Alzheimer’s (AD), emphasized LipiDiDiet trial. feasibility effects multimodal...
Social activities are important for health and act as a driver of cognitive reserve during aging. In this perspective paper, we describe challenges outline future (research) endeavors to establish better operationalization social in multidomain interventions prevent dementia.
Abstract Background Multimodal lifestyle interventions can benefit overall health, including cognition, in populations at-risk for dementia. However, little is known about the effect of patients with prodromal Alzheimer’s disease (AD). Even less dietary intake and adherence to recommendations within this population making it difficult design tailored them. Method A 6-month MIND-AD mini pilot randomized controlled trial (RCT) was conducted among 93 participants AD Sweden, Finland, Germany,...
This is the study plan of Karolinska NeuroCOVID study, a neurocognitive impairment after severe COVID-19, relating post-intensive care unit (ICU) cognitive and neurological deficits to biofluid markers MRI. The COVID-19 pandemic has posed enormous health challenges individuals health-care systems worldwide. An emerging feature that temporary extended impairment, exhibiting myriad symptoms signs. causes this symptomatology have not yet been fully elucidated.In we aim investigate patients...
Sedentary behavior (SB) is defined as a mean of >6 hours daytime sitting or lying down. SB has been shown to increase with older age and risk factor for disease. During the transition from working life retirement, changes in daily activities occur, risking increased SB. The aim present study was gain deeper understanding relation retirement experienced by persons retirement.The grounded phenomenological life-world perspective. Fourteen semi-structured interviews were conducted participants...
Alzheimer's disease (AD) is one of the world's leading public health challenges. One-third AD cases are attributable to modifiable vascular and lifestyle-related risk factors. The Multimodal Preventive Trial for Disease, MIND-AD
Abstract Background Communication in healthcare has been extensively studied, but most research focused on miscommunication and the importance of communication for patient safety. Previous interprofessional mainly relationships between physicians nurses non-psychiatric settings. Since is one core competencies psychiatric care, more other clinicians needed, should be explored from a broader perspective. This study aimed to explore describe outpatient unit. Method During spring 2022, data...
Abstract Background The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) multimodal lifestyle intervention yielded cognitive other health benefits in older adults at risk of decline. two-year multinational randomized controlled LETHE trial evaluates the feasibility a digitally supported, adapted FINGER among at-risk adults. Technology is used complement in-person activities, streamline delivery, personalize recommendations, collect digital...
Everyday person transfer situations involving persons with dementia and their caregivers can be reciprocally problematic. Group interviews professional were conducted, focusing on the caregivers’ experiences of singing during residents dementia, a qualitative content analysis was performed. The expressed that compared to everyday without singing, there obvious differences singing. When caregiver sang, communication mutually enhanced between residents. Caregivers reported seemed show true...
Everyday person transfer situations involving persons with dementia and their caregivers can be reciprocally problematic. Group interviews professional were conducted, focusing on the caregivers’ experiences of singing during residents dementia, a qualitative content analysis was performed. The expressed that com- pared to everyday without singing, there obvious differences singing. When caregiver sang, communication mutually enhanced between residents. Caregivers reported seemed show true...
Mobility problems and cognitive deficits related to transferring or moving persons suffering from dementia are associated with dependency. Physical assistance provided by staff is an important component of residents’ maintenance mobility in care facilities. Unfortunately, hands-on during transfers also a source confusion dementia, as well strain the caregiver. The bidirectional effect actions dyad involved transfer complicated evaluate. This study aimed develop assessment scale for measuring...
Background: Sarcopenia and cognitive impairment are two leading causes of disabilities. Objective: The objective was to examine the prevalence sarcopenia investigate association between diagnostic components (muscle strength, muscle mass, physical performance) in memory clinic patients. Methods: 368 patients were included (age 59.0±7.25 years, women: 58.7%), displaying three clinical phenotypes impairments, i.e., subjective (SCI, 57%), mild (MCI, 26%), Alzheimer’s disease (AD, 17%). defined...
Purpose: This study describes caregivers’ experiences of person transfer situations involving people with dementia. Method: Qualitative focus group interviews were conducted a total 10 caregivers; two groups five persons each, including men and eight women. The resulting data extracted condensed into meaning units codes using content analysis. Findings: One main theme was formulated that represents the dementia: “Reciprocal struggle in tasks”. Five categories formulated: “Becoming familiar...
Abstract Background Persons with dementia living in nursing homes need assistance moving and transfers; however, caregivers assisting persons their daily person transfers report strain-related complicated transfer-related behavioural problems. The reciprocity of complex dyadic behaviours is affected by environmental factors, the health status caregiver’s skills knowledge. aim this study was to explore tailored interventions guided a functional behaviour analysis for problematic transfer...
The study aimed to explore how home help service staff described their role in improving the abilities of older people, particular, women with chronic pain who are dependent on formal care, perform everyday activities. Three focus group interviews were conducted, and a qualitative inductive thematic content analysis was used. resulted one theme: struggling improve care recipients’ opportunities for independence but being inhibited by complex environmental factors. By encouraging recipients...
Aim: To study the inter- and intra-rater reliability of a newly developed assessment scale, Dyadic Interaction in Dementia Transfer Assessment Scale (DIDTAS). Methods: Two physiotherapists completed observational form DIDTAS while watching 20 video-films sit-to-stand-transfers or bedside transfers (i.e., caregiver-assisted transfers), videotaped dementia special care unit. Two-way analyses variance (ANOVAs) were used for calculating ICC values each item. Results: The results supported...
Background: Impaired mobility in people with severe dementia is well known. Physical therapists play a key role guiding professional caregivers on how to handle and transfer-related problems; however, it unknown the complexity of dementia-related impaired endurance, joint dysfunction, balance, gait dysfunction at same time, take into consideration person's decreased cognition, communication deficits, behaviour problems.Aims methods: The aim was explore effectiveness efficiency functional...
Abstract Background The positive results of the landmark Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability ‐ FINGER, 2‐year lifestyle‐based intervention up 11 years follow‐up ‐, followed by Multimodal Preventive Trial for Alzheimer’s Disease MIND‐ADmini, 6‐month + medical food, 1‐year provided foundation advance multimodal trials dementia prevention within World‐Wide FINGERS (WW‐FINGERS) network. Innovative should involve tailored approaches, combining...
Communication in healthcare extends beyond patient care, impacting the work environment and job satisfaction. Interprofessional communication is essential for fostering collaboration, but challenges arise from differences training, roles, hierarchies. The study aimed to explore psychiatric outpatient clinicians' experiences of interprofessional their perceptions how intersects organizational social healthcare. Qualitative research involved focus group interviews with clinicians five units...
Abstract Background The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) multimodal lifestyle intervention yielded cognitive other health benefits in older adults at risk of decline. two‐year multinational randomized controlled LETHE trial evaluates the feasibility a digitally supported, adapted FINGER among at‐risk adults. Technology is used complement in‐person activities, for delivery, personalize recommendations, collect digital biomarkers....