- Selenium in Biological Systems
- Plant Micronutrient Interactions and Effects
- Trace Elements in Health
- Skin Protection and Aging
- Dendrimers and Hyperbranched Polymers
- Heavy metals in environment
- Acne and Rosacea Treatments and Effects
- Autoimmune Bullous Skin Diseases
- RNA Interference and Gene Delivery
- Autoimmune and Inflammatory Disorders
- Dermatology and Skin Diseases
- melanin and skin pigmentation
- Hair Growth and Disorders
- Retinoids in leukemia and cellular processes
- Advancements in Transdermal Drug Delivery
- Cancer and Skin Lesions
- Genetic and rare skin diseases.
- Luminescence and Fluorescent Materials
- Fungal Infections and Studies
- Dermatologic Treatments and Research
- Infective Endocarditis Diagnosis and Management
- Mast cells and histamine
- Antioxidant Activity and Oxidative Stress
- Crop Yield and Soil Fertility
- Heavy Metals in Plants
Medical University of Lublin
2016-2022
University of Białystok
2017
Bydgoszcz University of Science and Technology
2002-2014
Poznan University of Medical Sciences
2014
Bronisław Markiewicz State Higher School of Technology and Economics in Jarosław
2014
University of Information Technology and Management in Rzeszow
2010-2013
Wojskowy Instytut Medyczny
2006
Acne is a very common and disfiguring disease that affects mostly adolescents and, to some extent, adults. The objective of our study was estimate the adverse effects after isotretinoin by treatment 3,525 patients due acne vulgaris in 5-year observation. Retrospective, comparative carried out Poland Romania from January 2012 August 2016. Inclusion criteria into this were moderate, severe, nodulocystic inflammatory vulgaris. Exclusion mild acne, pregnant, lactating women. Statistical analysis...
Polyamidoamine PAMAM dendrimer generation 3 (G3) was modified by attachment of biotin via amide bond and glucoheptoamidated addition α-D-glucoheptono-1,4-lacton to obtain a series conjugates with variable number residues. The composition determined detailed 1-D 2-D NMR spectroscopy reveal the residues, which were 1, 2, 4, 6, or 8, while glucoheptoamide residues substituted most remaining primary amine groups G3. then used as host molecules encapsulate 5-aminolevulinic acid. solubility acid...
Many factors influence the persistence of traces pharmaceuticals in aqueous environments.Most important are intensity light and presence inorganic ions as well organic matter.We studied impact some environmental (humic acids, NO 3 -and 2 -ions, solar intensity, ambient pH) on stability kinetics photo-reactions paracetamol, naproxen, diclofenac.It was stated that paracetamol photoresistant, while naproxen diclofenac were photoliable.An addition -ions or humic acid strongly inhibited...
Abstract The topical contact sensitiser diphenylcyclopropenone ( DCP ) remains one of the most effective treatment modalities for alopecia areata AA ). However, some patients (nonresponders) do not respond to this because they have an allergic reaction . aim study was investigate potential role imiquimod in inducing nonresponders. In all, 20 nonresponders were recruited from a group ‐treated patients. Of these patients, 10 treated with and alone. A significantly better therapeutic outcome...
Aim. This study aimed to examine the influence of maturation and dosage on sedative haemodynamic response observed in rabbits after administration dexmedetomidine. Material methods. The pharmacodynamics dexmedetomidine was studied 14 healthy New Zealand white at three periods maturation; stage 1–1.5 months old, 2–2.5 old 3–6.5 ones. administered dose ranged from 25 µg/kg 300 body weight. pedal withdrawal reflex used measure duration anaesthesia. heart rate mean arterial pressure were...
Abstract Lepidium meyenii , commonly known as Maca, is a Peruvian plant that grows high in the Andes, areas over 4,000 meters above sea level. Its composition contains almost all of essential amino acids and twenty fatty needed by man, well many vitamins, minerals several sterols glucosinolates. The specific unique unsaturated amides found only this are macaenes macamides. Most valuable ingredients contained within hypocotyls. Maca comes three forms, based on its root colour, yellow, red...
Statins are widely used to lower plasma concentrations of lipids, e.g. cholesterol. One the main effects statin treatment is inhibition hydroxymethyl glutaryl-coenzyme A reductase. The role fluvastatin, a frequently statin, was examined in potential modulation tyrosinase (key enzyme melanogenesis) synthesis. Levels mRNA induced by UVB irradiation B16F10 melanoma cell line were measured real time PCR. Fluvastatin increases production line. may potentially influence melanin synthesis and...
The aim of the research was to determine effect fertilisation applying various doses manure and nitrogen on selenium content soil against a background catalase dehydrogenase activity. experiment conducted using crop rotation system of: potato–winter wheat+intercrop –spring barley+undersown red clover+grasses. treated with organic in form under potato at 0, 20, 40, 60 80 t·ha −1, 120 kg N·ha −1. A supplement −1 resulted greatest significant increase total ∼100% compared from control plots. We...
Acne vulgaris is a chronic inflammatory skin disease of the pilosebaceous follicles that affects patients all ages.Use isotretinoin in early stages to prevent subsequent lesions acne, including prolonged treatment and acne scars at later age.A retrospective, comparative study was carried between January 2010 November 2018. The population consisted 90 children aged 9-18 years with acne. During by clinical evaluation done every month. Patients were divided into three groups according age. One...
Background: Oral isotretinoin is the only drug which promotes prolonged remission or cure of severe acne. The aim our study was to estimate exposure and evaluate effectiveness Polish Romanian pregnancy prevention. This a comparative two groups women. Methods: A retrospective, 569 women with acne vulgaris. included randomly selected during treatment follow-up. Group I rigorous prevention pregnancy; II without this rigor. Results: We did not register any pregnancies. 1.93% used oral...
(1) Background: Isotretinoin (ISO) is a systemic retinoid known for its teratogenic effects on embryos and fetuses. The aim of this study was to compare the pregnancy outcomes women who were exposed isotretinoin with those without such exposure from point view. (2) Methods: A total 1459 female patients three clinical hospitals in Poland Romania, segregated into two groups depending their ISO exposure, evaluated between January December 2019. Medical records screened identify congenital...
Abstract Betel quid is one of the most commonly used psychoactive substances in world, especially among Asian communities, just after caffeine, nicotine and alcohol. The mixture that chewed usually contains betel leaves, areca nut slaked lime, nonetheless, its ingredients preparation manner tend to vary. Areca four main alkaloids - arecoline, arecaidyne, guvacine guvacoline are responsible for effects. act chewing might have a negative impact on an overall health can cause pathological...
Cutaneous T cell lymphoma (CTCL) is a rare group of lymphoproliferative disorders characterized by localization lymphocytes to the skin.The most common subtype CTCL mycosis fungoides (MF) [1].Figure 3: Neck area with swollen lymph nodes and exfoliative dermatitis.