A5045866190- Pneumonia and Respiratory Infections
- Respiratory viral infections research
- Bacterial Infections and Vaccines
- SARS-CoV-2 and COVID-19 Research
- Viral gastroenteritis research and epidemiology
- Power System Reliability and Maintenance
- Kawasaki Disease and Coronary Complications
- Electric Power System Optimization
- Animal Virus Infections Studies
- Vaccine Coverage and Hesitancy
- Virus-based gene therapy research
- Sepsis Diagnosis and Treatment
- Urinary Tract Infections Management
- Optimal Power Flow Distribution
- Liver Disease Diagnosis and Treatment
- Immune Cell Function and Interaction
- Central Venous Catheters and Hemodialysis
- Pediatric Urology and Nephrology Studies
- Neonatal and Maternal Infections
- Ethics in Clinical Research
- Power System Optimization and Stability
- Gastrointestinal Tumor Research and Treatment
- Viral Infections and Immunology Research
- Asthma and respiratory diseases
- Patient-Provider Communication in Healthcare
Patan Academy of Health Sciences
2016-2024
Patan Hospital
2021
Kathmandu University
2010-2016
Neonatal sepsis, one of the leading causes mortality in neonatal intensive care units (NICU) developing countries like Nepal, is often not extensively studied. In order to decrease morbidity and associated with neonatologists should have a keen knowledge existing bacteriological flora their antibiotic susceptibility pattern. this study, we aim determine profile pattern culture positive sepsis NICU tertiary teaching hospital Nepal. This was retrospective cross-sectional study all blood cases...
Previously, the Vi-typhoid conjugate vaccine (Vi-TT) was found to be highly efficacious in Nepalese children under 16 years of age. We assessed immunogenicity Vi-TT at 9 and 12 months age response a booster dose 15
In Nepal, Streptococcus pneumoniae (pneumococcus) is a common cause of bacterial pneumonia in children, and major health concern. There are few data on the effect vaccination disease or colonisation with pneumococci nasopharynx children this setting. The 10-valent pneumococcal conjugate vaccine (PCV10) was introduced into routine infant immunisation schedule Nepal 2015. We aimed to investigate introduction PCV10 carriage Nepal.We did an observational cohort study Nepal. hospital surveillance...
Introductions: Urinary tract infection (UTI) is a common bacterial affecting children. A prompt recognition and accurate antimicrobial management are vital to prevent kidney damage. This study aims determine the pathogens their patterns of resistance in children presenting with UTI.Methods: was cross sectional done at Patan Hospital, Academy Health Sciences, from Nov 2012 Oct 2016. There were 88 between age group 1 14 years culture proven UTI. The antibiotic analysed.Results: Three most...
Invasive bacterial disease (IBD; including pneumonia, meningitis, sepsis) is a major cause of morbidity and mortality in children low-income countries.We analyzed data from surveillance study suspected community-acquired IBD <15 years age Kathmandu, Nepal, 2005 to 2013 before introduction pneumococcal conjugate vaccines (PCV). We detailed the serotype-specific distribution invasive (IPD) incorporated antigen PCR testing cerebrospinal fluid (CSF) with meningitis.Enhanced was undertaken during...
The rural areas in developing countries mostly rely on conventional non-commercial fuels like woods, forest byproducts, agricultural residue and animal wastes. But the requirements for commercial kerosene eats away their petty incomes. In this regard, paper investigates basis of a case study adequacy Hybrid Solar Wind Power System. Among various renewable resources, hybrid solar wind energy seems to be promising solutions provide reliable power supply with improved system efficiency...
SETTING: Patan Hospital, a tertiary care hospital in Lalitpur District, Nepal. OBJECTIVES: To describe the annual parenteral antibiotic consumption 1) defined daily dose (DDD) and DDD per 100 admissions; 2) calculate admissions proportions by pharmacological subgroup, chemical subgroup AWaRe categories; 3) patient expenditure on antibiotics as proportion of total drugs consumables between 2017 2019. DESIGN: This was cross-sectional study. RESULTS: Total increased 23% from 39,639.7 to...
Integration of wind turbines may have significant impacts on power system operation. Generation electricity from has received considerable attention. Induction machines are the one which widely used as generators in based generations. This paper analyzes impact integrating generation voltage collapse and loading parameters network Kathmandu valley, Nepal. These requirements simulated compared for study cases with without included into year 2008/09. The stability valley is determined by its...
The task of this research work is to determine an optimal network configuration according load growth. It determines where, when and how many new transmission lines should be installed. This study presents a methodology for expansion planning using DC power flow model. objectives are minimize the investment cost, line operation maintenance cost minimizes generation cost. Mixed Integer Linear Programming method used solve Transmission Line Expansion problem. Firstly Garver's Test System then...
Reduction in detection of asymptomatic carriage Haemophilus influenzae type b (Hib) can be used to assess vaccine impact. In Nepal, routine vaccination against Hib children at 6, 10, and 14 weeks age was introduced 2009. Before introduction, estimated 5.0% among aged <13 years with higher rates under 5. Large-scale evaluation has not been investigated since the introduction pentavalent diphtheria-tetanus-pertussis/Hib/hepatitis B (DTP-Hib-HepB) Nepal.A total 666 oropharyngeal swabs were...
In the era of growing antimicrobial resistance, there is a concern about effectiveness first-line antibiotics such as ampicillin in children hospitalized with community-acquired pneumonia. this study, we describe antibiotic use and treatment outcomes among under-five pneumonia admitted to tertiary care public hospital Nepal from 2017 2019. cross-sectional study involving secondary analysis data, were 659 patients 30% them had history prehospital use. Irrespective use, monotherapy (70%) was...
Hepatitis A virus infection is typically an acute self-limiting illness associated with general nonspecific symptoms such as fever, malaise, anorexia, nausea, vomiting, abdominal pain or discomfort,and diarrhea. This may have atypical manifestation like prolonged cholestasis. Despite havingvarying typical and manifestations a case present life-threatening bleedingfrom co-existing surgical cause perforation of Meckel’s diverticulum.
Inactivated, viral vector and mRNA vaccines have been used in the Nepali COVID-19 vaccination programme but there is little evidence on effectiveness of these this setting. The aim study to describe vaccine Nepal provide information infections with SARS-CoV-2 variants. This a hospital-based, prospective test-negative case-control conducted at Patan Hospital, Kathmandu. All patients >18 years age presenting Hospital COVID-19-like symptoms who received antigen/PCR test are eligible for...
Abstract Background Universal immunisation is the cornerstone of preventive medicine for children, The World Health Organisation (WHO) recommends diphtheria-tetanus-pertussis (DTP) vaccine administered at 6, 10 and 14 weeks age as part routine immunisation. However, globally, more than 17 unique DTP-containing schedules are in use. New vaccines other diseases continue to be introduced into infant schedule, resulting an increasingly crowded schedule. OptImms trial will assess whether antibody...
Background Cigarette smoking is one of the cardinal causes for development bronchial hyperresponsiveness among smokers. Objectives This study was perspectively designed to determine peripheral responsiveness sub-maximal exercise challenge in asymptomatic Methods The subjects were between age 18-25 years without any findings cardio-respiratory diseases. We performed 5 min step test at intensity 80 90% maximum predicted heart rate 42 young adult male smokers examine effect cigarette on airway...