Abdulsalam Alkhudhayri

ORCID: 0000-0003-0972-9474
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About
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Research Areas
  • Coccidia and coccidiosis research
  • Nanoparticles: synthesis and applications
  • Parasitic Infections and Diagnostics
  • Selenium in Biological Systems
  • Helminth infection and control
  • Insect Pest Control Strategies
  • Medicinal Plants and Neuroprotection
  • Bee Products Chemical Analysis
  • Healthcare and Venom Research
  • Anesthesia and Neurotoxicity Research
  • Insect and Pesticide Research
  • Gastrointestinal disorders and treatments
  • Hepatitis B Virus Studies
  • Animal Diversity and Health Studies
  • Brucella: diagnosis, epidemiology, treatment
  • T-cell and Retrovirus Studies
  • Ga2O3 and related materials
  • Animal Disease Management and Epidemiology
  • Helicobacter pylori-related gastroenterology studies
  • Graphene and Nanomaterials Applications
  • Advanced Photocatalysis Techniques
  • Burkholderia infections and melioidosis
  • Magnesium Oxide Properties and Applications
  • Neuroscience and Neuropharmacology Research
  • Moringa oleifera research and applications

University of Hafr Al-Batin
2021-2024

King Saud University
2020

Antimicrobial resistance is one of the largest medical challenges because rising frequency opportunistic human microbial infections across globe. This study aimed to extract chitosan from exoskeletons dead bees and load it with bee venom (commercially available as Apitoxin [Api]). Then, ionotropic gelation method would be used form nanoparticles that could a novel drug-delivery system might eradicate eight common pathogens (i.e., two fungal six bacteria strains). It also treat colon cancer...

10.3389/fmicb.2024.1345478 article EN cc-by Frontiers in Microbiology 2024-03-15

Although elemental selenium has been found to be effective against Eimeria, no study yet investigated the effects of nanoparticles (SeNPs) on Eimeria parasite. The aim this study, therefore, was evaluate ameliorative effect SeNPs compared with mice jejunum infected sporulated oocysts papillata.The were divided into 4 groups, first being non-infected, control group, and second, third, fourth groups orally inoculated 1,000 E. papillata. third also received, respectively, an oral dose 0.1 mg/kg...

10.2147/ijn.s162355 article EN cc-by-nc International Journal of Nanomedicine 2018-04-01

This investigation was designed to assess the cytotoxic and apoptotic effects of selenium nanoparticles. It explored nanoparticles in MCF-7 HepG2 cell lines. The morphology analyzed by transmission electron microscopy (TEM) verify their size crystalline properties. were almost spherical cubic shape (∼20 nm). Selenium tested for activity lines using MTT NRU assays. We found relative differences vulnerability both response nanoparticle-induced cytotoxicity. Specifically, cells exhibited...

10.1166/nnl.2020.3115 article EN Nanoscience and Nanotechnology Letters 2020-03-01

Eimeriosis is caused by a protozoan parasite of the genus Eimeria and infection affecting most domestic animal species. The aim this research was to comprehend impact selenium nanoparticles (SeNPs) on eimeriosis induced papillata in mouse jejunum, how they work as antioxidants anti-apoptotic agents against eimeriosis. numbers meronts, gamonts, developing oocysts E. reduced after infected mice were treated with SeNPs. levels malondialdehyde (MDA), nitric oxide (NO), other oxidative...

10.1590/0001-3765202020191107 article EN cc-by Anais da Academia Brasileira de Ciências 2020-01-01

In recent investigations, secondary bacterial infections were found to be strongly related mortality in COVID-19 patients. addition, Pseudomonas aeruginosa and Methicillin-resistant Staphylococcus aureus (MRSA) bacteria played an important role the series of that accompany infection COVID-19. The objective present study was investigate ability biosynthesized silver nanoparticles from strawberries (Fragaria ananassa L.) leaf extract without a chemical catalyst inhibit Gram-negative P....

10.3389/fmicb.2023.1142646 article EN cc-by Frontiers in Microbiology 2023-04-06

Coccidiosis affects both domestic and wild animals negatively impacting industries worldwide. Medicinal plants are widely used against parasites. Using infected mice with Eimeria papillata, we assessed the anticoccidial impact of Zingiber officinale extract (ZE). The in first group were just given distilled water, while second ZE. parasite's oocysts into third fourth groups. was ZE for five days. faeces reduced after treatment total parasitic stages treatments by about 50%. Also, gamonts,...

10.1016/j.sjbs.2022.02.025 article EN cc-by-nc-nd Saudi Journal of Biological Sciences 2022-02-18

Surra is a parasitic disease caused by the eukaryotic, unicellular hemoprotozoan, Trypanosoma evansi , which affects development of animal production and widespread among both domestic wild animals. As such, in this research, we studied antiparasitic activity ameliorative impact Eucalyptus camaldulensis leaf extracts (ELE) against T. -induced brain injury spleen immune response mice. result, found that ELE decreased amount trypanosomes blood improved weight loss infection. In addition,...

10.3389/fmicb.2022.833520 article EN cc-by Frontiers in Microbiology 2022-03-21

Despite previous studies showing that Helicobacter pylori influences iron consumption, it is unknown what causes deficiency anemia in response to H. infection. The goal of the study was find out whether having an infection with linked a drop-in serum level. Detection presented by serological test detect titers IgG and IgA blood serum. determination level performed using biochemistry spectrophotometry test. Additionally, full count done assess haemoglobin concentration establish patient...

10.1016/j.jksus.2022.102353 article EN cc-by Journal of King Saud University - Science 2022-10-06

This study targeted developing a novel Zinc oxide with alpha hematite nanoflowers (NFs)-loaded bee venom (Bv) (Bv-ZnO@αFe2O3 NFs) as bio-natural product from bees to combine both the advantages of combination magnetic properties and antimicrobial anti-biofilm on isolated coliform bacteria effluent wastewater treatment plants. About 24 isolates treated were multidrug resistant (MDR). The phylogenetic grouping Escherichia coli (E. coli) Klebsiella pneumonia (K. pneumonia) showed that largest...

10.3390/microbiolres14040102 article EN cc-by Microbiology Research 2023-09-27

Magnesium nanoparticles have been the focus of study over past few years because its functionality in body. Assessment impact magnesium oxide (MgNPs) on eimeriosis has yet to be conducted. The goal this was see how MgNPs affected parasite Eimeria papillata infected jejunum. To induce eimeriosis, mice were with sporulated oocysts. For treatment, 5 mg / Kg used for consecutive days. infection reduced number intestinal goblet cells and their associated genes MUC2 MUC4, as well increasing...

10.1016/j.sjbs.2021.09.034 article EN cc-by-nc-nd Saudi Journal of Biological Sciences 2021-09-17

The exploration of natural materials for the production nanoparticles against parasites is currently particular interest due to its ecofriendly nature. In this study, we described biosynthesis silver derived from methanolic garlic extract. Infrared spectroscopy and GC-Mass spectrometry were used screen phytochemical composition figure out how much active components. Allium sativum extract (ASE) ASE loaded in (Bio-AgNPs) treat helminthiasis vitro. Three doses (100, 50 25 mg/mL) three...

10.1590/fst.123622 article EN Food Science and Technology 2023-01-01

The zinc oxide (ZnO) nanostructures are highly influential material and exhibit numerous properties. Numerous physicochemical applications for instance electronic, catalyst, solar cells, hydrogen fuels energy evolution. Besides the large application in various directions very few reports available cytotoxic evaluations their compression with nano particles (NPs) nanrorods (NRs) against breast (MCF-7) cancer cells. ZnO-NPs NRs were produced through solution process a short time span well...

10.1016/j.jksus.2021.101797 article EN cc-by-nc-nd Journal of King Saud University - Science 2021-12-25

Human brucellosis is the most common zoonotic disease in world. It infectious Najran region, south western of Saudi Arabia. Several studies emphasized on role biochemical and hematological markers clinical diagnosis brucellosis, however to best our knowledge this first study that has been carried out city. This aimed assess utility peripheral blood early infected patients. As well as, determine contributing value differential brucellosis. A cross sectional (October 2019 May 2020) had out....

10.1016/j.jksus.2022.102138 article EN cc-by-nc-nd Journal of King Saud University - Science 2022-05-30

Abstract This study aimed to evaluate the prevalence and trends of transfusion-transmitted infections (TTIs) in two hospitals Riyadh, as well judge best type tests ensure blood transfusion safety. By using serological nucleic acid test (NAT) tests, these donors were screened for human immunodeficiency virus (HIV), hepatitis C (HCV), B (HBV), T-lymphotropic 1 (HTLV-1), 2 (HTLV-2), syphilis, malaria infection a first time donation. Out 58,898 units, 336 units reacted HBsAg, 5,318 HBcAbs, 506...

10.1515/chem-2022-0351 article EN cc-by Open Chemistry 2023-01-01

The current work displayed the efficacy of nanodisk shaped zinc oxide nanostructures (NDs-ZnONSs) processed via hydrothermal solution process and studies cytotoxicity against human breast cancer cells (MCF-7). NDs-ZnONSs were analyzed by using instruments such as X-ray diffraction pattern (XRD), Field emission scanning electron microscopy (FESEM), Fourier transform infra-red spectroscopy (FTIR). XRD FESEM shows crystallinity morphology states estimated width size each sheet diameter length...

10.1080/17458080.2023.2228494 article EN cc-by Journal of Experimental Nanoscience 2023-06-30
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