- Antimicrobial Resistance in Staphylococcus
- Bacterial biofilms and quorum sensing
- RNA and protein synthesis mechanisms
- Antibiotic Resistance in Bacteria
- Bacterial Identification and Susceptibility Testing
- Antifungal resistance and susceptibility
- Gut microbiota and health
- Urinary Tract Infections Management
- Reproductive tract infections research
- Streptococcal Infections and Treatments
- Nosocomial Infections in ICU
- Bacteriophages and microbial interactions
- Oral microbiology and periodontitis research
- Salivary Gland Disorders and Functions
- Mycobacterium research and diagnosis
- Microbial Natural Products and Biosynthesis
- Pneumonia and Respiratory Infections
- Infective Endocarditis Diagnosis and Management
- Orthopedic Infections and Treatments
- Microbial Metabolism and Applications
University of Catania
2010-2021
Abstract The healthy vaginal microbiota is dominated by Lactobacillus spp., which provide an important critical line of defense against pathogens, as well giving beneficial effects to the host. We characterized L . gasseri 1A‐TV, fermentum 18A‐TV, and crispatus 35A‐TV, from premenopausal women, for their potential probiotic activities. antimicrobial 3 strains combination clinical urogenital bacteria were evaluated together with activities metabolites produced cell‐free supernatants (CFSs)....
Despite 10 years of clinical use, linezolid resistance in Staphylococcus aureus and coagulase-negative staphylococci (CoNS) is still a rare phenomenon. This study reports the mechanisms strain types seen clusters linezolid-resistant CoNS from two different hospitals Italy during period 2008-09.Genes associated with were subjected to molecular analysis isolates characterized by PFGE macrorestriction using SmaI.Thirty-three methicillin-resistant comprising epidermidis (24), hominis (5)...
Recent evidence has demonstrated that salivary molecules, as well bacterial populations, can be perturbed by several pathological conditions, including neuro-psychiatric diseases. This relationship between brain functionality and saliva composition could exploited to unveil new mechanisms of elusive diseases, such Autistic Spectrum Disorder (ASD). We performed a combined approach miRNA expression profiling NanoString technology, followed validation experiments in qPCR, 16S rRNA microbiome...
Rifampicin is one of the major drugs used on its own and also in combination to treat numerous infections sustained by methicillin-resistant Staphylococcus aureus (MRSA). In Italy, rifampicin resistance (RIF-R) increasing multidrug-resistant-MRSA isolates (16.4%), with respect Europe (5.7%). our study, relationship between clones, rpoB mutations, susceptibility profiles 50 RIF-R MRSA isolated from hospitalized patients was evaluated. Antimicrobial testing performed broth microdilution...
ABSTRACT In order to assess the frequency of clinically relevant linezolid-resistant staphylococcal isolates, and role linezolid in maintaining coselecting multiple resistance mechanisms ( cfr , 23S rRNA, L3/L4 mutations), a prospective Italian study was performed from 2010 2011 confirm diffusion three major multidrug-resistant clones (ST2, ST5, ST23).
Abstract Methicillin‐resistant S. aureus has been reported as the main pathogen involved in chronic infections, osteomyelitis, and prosthetic joint infections. The host/pathogen interaction is dynamic requires several changes to promote bacterial survival. Here, we focused on internalization persistence behavior of well‐characterized Staphylococcus invasive strains belonging ST‐MRSA‐SCC mec clones. To overcome limitations cell culture method, comparatively analyzed ability within human MG‐63...
The commercial multi-pathogen probe-based real-time PCR SeptiFast (SF) was evaluated as a rapid and complementing tool for the microbiological diagnosis of bloodstream infections (BSIs) in series 138 matched blood samples from 65 patients with bacteraemia, hospitalized an intensive care unit, when antibiotics had already been administered. SF positive 32.6 % samples, whereas culture (BC) 21.7 (P < 0.05). identified more pathogens (11 versus 5; specificity, 90.7 %) reduced time aetiological...