A5073032229- Heart Failure Treatment and Management
- Cardiovascular Function and Risk Factors
- Potassium and Related Disorders
- Liver Disease and Transplantation
- Dialysis and Renal Disease Management
- Sepsis Diagnosis and Treatment
- Acute Kidney Injury Research
- Mechanical Circulatory Support Devices
- COVID-19 and healthcare impacts
- Metabolomics and Mass Spectrometry Studies
- Renal function and acid-base balance
- Cardiovascular and exercise physiology
- Electrolyte and hormonal disorders
- Cardiac Health and Mental Health
- Blood Pressure and Hypertension Studies
- Erythropoietin and Anemia Treatment
- Cardiac Arrest and Resuscitation
- Iron Metabolism and Disorders
- Acute Myocardial Infarction Research
- Liver Disease Diagnosis and Treatment
- Stuttering Research and Treatment
- Diabetes Treatment and Management
- Hemoglobinopathies and Related Disorders
- Ultrasound in Clinical Applications
- GDF15 and Related Biomarkers
Acute heart failure (AHF) critically deranges haemodynamic and metabolic homoeostasis. Iron is a key micronutrient for homoeostasis maintenance. We hypothesized that iron deficiency (ID) defined as depleted stores accompanied by unmet cellular requirements would in this setting predict the poor outcome. Among 165 AHF patients (age 65 ± 12 years, 81% men, 31% de novo HF), ID diagnosis we prospectively applied: low serum hepcidin reflecting (<14.5 ng/mL, 5th percentile healthy peers),...
In our retrospective study, we aimed to investigate the relationship between urinary chloride (uCl-) and selected clinical laboratory biomarkers, renal function, patient outcomes in acute heart failure (AHF) population. We divided 248 adult patients (≥ 18 years) with AHF into two groups: low uCl- (< 115 mmol/L) high uCl-. The mean age of group was 70.2 ± 12.6, 182 were male (73.4%). Clinical endpoints included in-hospital mortality, one-year a composite endpoint mortality rehospitalization...
INTROduCTIONAcute heart failure (AHF) is associated with multiorgan dysfunction, which may unfavorably affect prognosis.ObjECTIvEs We investigated the prevalence, clinical determinants, and prognostic consequences of abnormal liver function tests (LFTs) in population AHF. PATIENTs ANd mEThOdsWe conducted a retrospective analysis patients AHF, whom following LFTs were performed on admission: serum bilirubin, aspartate transaminase (AST), alanine (ALT), albumin.Abnormal defined as elevation...
Although renin-angiotensin-aldosterone system (RAAS) activation is believed to be the major driver of acute heart failure (AHF) episodes our understanding its prevalence and clinical relevance in contemporary settings incomplete.Serum renin aldosterone were measured at day-1 discharge patients (n = 211) that hospitalized between 2016 2017 for AHF a single cardiology center. The population was profiled based on upper limits normal (ULN) both biomarkers assessed linked with course outcomes.The...
The perception of acute heart failure (AHF) as a single entity is increasingly outdated, distinct patient profiles can be discerned. Key (HF) studies have previously highlighted the difference in both course and prognosis de novo AHF decompensated chronic HF (ADHF). Accordingly, with differing underlying pathophysiologies disease progression shown. We compared range selected biomarkers order to better describe profile ADHF, including inter alia—serum lactate, bilirubin, matrix...
Abstract Aims Despite attempts to improve the management of patients with acute heart failure (HF), virtually all therapeutic agents investigated in large clinical trials failed show any consistent reduction mortality and morbidity. Complexity syndrome HF seems be likely an underlying explanation. Traditionally, studied mixed patient populations HF, only recently, better characterization has been proposed. Dyspnoea is most common presenting symptom related hospital admission for HF. Whether...
Abstract Aims Patients with acute heart failure (AHF) are included into clinical trials regardless of differences in baseline characteristics. The aim this study was to assess patients AHF according the presence central and/or peripheral congestion at hospital admission and evaluate treatment response outcomes studied phenotypes. Methods results We investigated retrospectively 352 (mean age: 68 ± 13 years, 77% men) hospitalized due signs on admission. were divided type three groups: A,...
Introduction: Multi-organ damage often complicates an episode of acute heart failure (AHF) and worsens prognosis. It may result from hemodynamic disturbances leading to hypoperfusion tissue hypoxia. Lactate as a product anaerobic metabolism be used marker hypoxic stress. Aim: We aim determine the prevalence elevated serum lactate in AHF population, its relation hemodynamics, organ patient's outcome. Methods: An analysis patients admitted our hospital between Jan 2009-Oct 2010 whom derived...