To investigate the ameliorative effects and mechanism of Lycium barbarum polysaccharide (LBP) on growth performance, oxidative stress, lipid deposition in common carp (Cyprinus carpio) fed with high-fat diets, fish an initial weight 5.29 ± 0.12 g were divided into five experimental groups—including normal-fat diets—supplemented LBP (0.5, 1.0, 2.0 g/kg) for 8 weeks. The results showed that diets resulted significant decreases final body weight, gain rate, specific rate fish, as well causing a...

This study investigated the effects of Clostridium butyricum (CB) and sodium butyrate (SB) on growth performance, intestinal immune, gut microbiota mirror carp (Cyprinus carpio) fed with a high level soybean meal. Three hundred sixty healthy fingerlings (∼3.74 g) were divided into eight dietary treatments four replicates ten fish per replicate. Which include basal diet (Control group, C0); C0 supplemented three levels CB, 3 × 107 cfu/kg (C1), 108 (C2), 109 (C3); SB, 500 mg/kg (S1), 1000...

A bioflocculant-producing bacterium, Bacillus megaterium SP1, was isolated from biofloc in pond water and identified by using both 16S rDNA sequencing analysis a Biolog GEN III MicroStation System. The optimal carbon nitrogen sources for SP1 were 20 g L-1 of glucose 0.5 beef extract at 30°C pH 7. bioflocculant produced strain under culture conditions applied into aquaculture wastewater treatment. removal rates chemical oxygen demand (COD), total ammonia (TAN), suspended solids (SS) reached...

Varying dietary inclusion levels of fish protein hydrolysates (FPH) were applied in a feeding experiment with juvenile largemouth bass ( Micropterus salmoides ) to assess their effects on growth, intestinal antioxidant status, immunity, and microflora. FPH added 4 levels: 0 g/kg (control group, FPH-0), 10 (FPH-10), 30 (FPH-30), 50 (FPH-50) dry matter, respectively substituting 0, 5.3, 16.3, 27.3% meal meal. Quadruplicate groups 25 initial body weight 9.51 ± 0.03 g fed during the 56-day...

High-fat diet is regarded as crucial inducers of oxidative stress, inflammation, and metabolic imbalance. In order to investigate the ameliorative potential resveratrol against progression liver injury towards steatohepatitis, common carp (Cyprinus carpio) were distributed into six experimental groups fed with a normal-fat diet, high-fat supplemented (0.8, 1.6, 2.4, 3.2 g/kg diet) for 8 weeks. The decreased antioxidant capacities, well causing inflammatory response lipid deposition carp....

This study was aimed to evaluate the antimicrobial resistance and molecular mechanisms of 87 Vibrio parahaemolyticus isolates from cultured sea cucumbers (Apostichopus japonicus). The results showed that all were resistant ampicillin cephazolin, fewer them streptomycin (43·7%), cefuroxime sodium (18·4%), tetracycline (4·6%), sulphamethoxazole/trimethoprim (2·3%) four quinolones (2·3%). More than half (56·2%) displayed multiple at least three antimicrobials. genes detected in...

The effect of the different dietary carbohydrate types and levels on growth performance, haematological indices hepatic hexokinase (HK) glucokinase (GK) genes expression involved in control glucose metabolism, was studied juvenile mirror carp (Cyprinus carpio). Two carbohydrates (glucose starch) diets with two (250 500 g kg−1) were fed to triplicate groups 35 fish for 60 days. best weight gain rate specific observed 250 kg−1 diet starch (P < 0.05). Fish showed low feed utilization, highest...

The Amur grayling ( Thymallus arcticus grubei Dybowski, 1869), a species of potentially economic and research value, is renowned for its tender meat, exquisite flavor, high nutritional contents. This study was conducted to investigate the physiological adaptation mechanisms dietary lipids in fry (with average initial weight 4.64±0.03 g). involved 56-day feeding trial with diets containing varying lipid levels (9.07%, 12.17%, 15.26%, 18.09%, 21.16%, 24.07%, designated as GL1 through GL6,...

The aim of this study was to assess the response characteristics intestinal immune function and microflora pike perch (Sander luciperca) receiving cottonseed protein concentrate (CPC) as a substitute for fishmeal. A basal diet formulated contain 55% fish meal, then CPC used replace 0% (CPC0), 20% (CPC1), 40% (CPC2), 60% (CPC3) dietary meal. four diets were fed pikeperch with an initial body weight 3.55 ± 0.01 g 8 weeks. results revealed that there no significant effects levels on survival...

Significant disparities between the features of natural images and those inherent to histopathological make it challenging directly apply transfer pre-trained models from histopathology tasks. Moreover, frequent lack annotations in patch has driven researchers explore self-supervised learning methods like mask reconstruction for representations large amounts unlabeled data. Crucially, previous mask-based efforts have often overlooked spatial interactions among entities, which are essential...

Previous studies provide comprehensive evidence of the environmental hazards and intestinal toxicity microcystin-LR (MC-LR) exposure. However, little is known about mechanisms underlying injury intestine exposed to MC-LR. Juvenile common carp (Cyprinus carpio) were MC-LR (0 10 μg/L) for 15 days. The results suggest that organic anion-transporting polypeptides 3a1, 4a1, 2b1, 1d1 mediate entry into tissues. Lesion morphological features (vacuolization, deformation dilation endoplasmic...

To investigate the effects of alpha-ketoglutarate (AKG) supplementation in a low protein (LP) diet on growth performance, immune response, and intestinal health common carp ( Cyprinus carpio ), 600 were randomly divided into five dietary groups: normal (NP) containing 32% crude protein, an LP formulated with 28% AKG at 0.4%, 0.8%, 1.2% (dry matter). After 8-week trial period, results demonstrated that led to decrease barrier function. Compared group, final body weight gain rate LP+0.4% group...

Carbonate alkalinity is a major environmental stress factor affecting aquatic feed configuration, which easily causes oxidative and hypoimmunity for fish. Hence, the purpose of study to assess potential effect phosphorus on growth, intestinal oxidation resistance, physical barrier function, microflora Songpu mirror carp ( Cyprinus carpio Songpu) (initial average weight 2.95 ± 0.21 g) reared at high-concentration carbonate environment. A two-factor, three-level (2 × 3) design was applied, in...

The application of cottonseed protein concentrate (CPC) is an effective strategy to moderate the shortage fish meal (FM) for aquafeed industry. However, little attention has been paid effects replacing fishmeal with CPC on cyprinid fish. This study used common carp (

This study was conducted to determine the effects of dietary α-ketoglutarate (AKG) supplementation on antioxidant defense system and gene expression heat shock protein (HSP) 70 HSP 90 in hybrid sturgeons Acipenser schrenckii ♀ × A. baerii ♂ exposed ammonia-N stress. A 2 3 factorial experiment arranged, which each diet (0%, 1% AKG) randomly assigned 0.25 (control) 5 10 mg L−1 groups with three replicate aquaria for 72 h. The significantly increased serum ammonia concentrations intestinal Gln...

As an intermediate substance of the tricarboxylic acid cycle and a precursor glutamic synthesis, effect alpha-ketoglutarate on growth protein synthesis has been extensively studied. However, its prevention treatment pathogenic bacteria mechanism have not yet noticed. To evaluate effects intestinal antioxidant capacity immune response Songpu mirror carp, total 360 fish with average initial weight 6.54 ± 0.08 g were fed diets containing 1% for 8 weeks. At end feeding trial, challenged...

An 82-day study was conducted to assess the effect of dietary lipid levels on growth performance, feed utilization, deposition, and hepatopancreas lipometabolism large-sized common carp ( Cyprinus carpio ). Six isonitrogenous (300 g/kg protein) pelletized diets with different (30, 60, 90, 120, 150, 180 g/kg) were fed in triplicate fish groups 75 individuals (with an initial mean weight 247.00 ± 16.67 g). The results showed that there a significant increase gain (WG) rate (WGR), specific...