- Muscle Physiology and Disorders
- Animal Nutrition and Physiology
- Genetic Mapping and Diversity in Plants and Animals
- interferon and immune responses
- MicroRNA in disease regulation
- Genetic and phenotypic traits in livestock
- Rice Cultivation and Yield Improvement
- Mycotoxins in Agriculture and Food
- Meat and Animal Product Quality
- Peroxisome Proliferator-Activated Receptors
- Animal Genetics and Reproduction
- Plant Disease Resistance and Genetics
- Cancer-related molecular mechanisms research
- Adipose Tissue and Metabolism
- Molecular Biology Techniques and Applications
- Immune Response and Inflammation
- RNA Research and Splicing
- RNA modifications and cancer
- Biochemical Analysis and Sensing Techniques
- RNA and protein synthesis mechanisms
- Aquaculture disease management and microbiota
- CRISPR and Genetic Engineering
- Immune Cell Function and Interaction
- Viral gastroenteritis research and epidemiology
- Animal Virus Infections Studies
Jilin University
2009-2025
Tianjin University
2022-2025
Yantaishan Hospital
2025
Tianjin Hospital
2025
Henan Academy of Agricultural Sciences
2025
Affiliated Hospital of Jining Medical University
2023-2025
Sichuan Agricultural University
2015-2024
Chinese Academy of Sciences
2023-2024
ZheJiang Academy of Agricultural Sciences
2024
Guangdong Pharmaceutical University
2007-2024
The Rac GTP-binding proteins are members of the Rho family and regulate growth factor-stimulated actin assembly in a variety cells. formation phosphorylated inositol lipids has been implicated control processes initiating regulating such polymerization. Associations with enzymes involved lipid metabolism have described. Here we demonstrate direct specific interaction phosphatidylinositol (PI) 3-kinase. This is dependent upon being GTP-bound state requires an intact effector domain. In...
Soybean cyst nematode (SCN, Heterodera glycines Ichinohe) is one of the most fatal pests soybean (Glycine max (L.) Merr.) worldwide and causes huge loss yield each year. Multiple sources resistance are urgently needed for effective management SCN via development resistant cultivars. The aim present study was to investigate genetic architecture HG Type 0 (race 3) 1.2.3.5.7 4) in landraces released elite cultivars mostly from China. A total 440 diverse were screened 1.2.3.5.7. Exactly 131 new...
Scope: Myogenesis involves a series of complex cellular and developmental processes regulated by many genes, transcription factors non-coding RNAs. Recent studies have demonstrated the involvement circular RNAs (circRNAs) in myogenesis. While previous established role for some circRNAs, precise functions mechanisms circRNAs skeletal muscle development are still not completely understood chicken. Methods: To identify potential during chicken embryonic development, rRNA- libraries sequencing...
T-2 toxin is type A trichothecenes mycotoxin, which produced by fusarium species in cereal grains. has been shown to induce a series of toxic effects on the health human and animal, such as immunosuppression carcinogenesis. Previous study proven that caused hepatotoxicity chicken, but regulatory mechanism unclear. In present study, we assessed toxicological effect apoptosis autophagy hepatocytes. The total 120 1-day-old healthy broilers were allocated randomly into four groups reared for 21...
MicroRNAs are evolutionarily conserved, small non-coding RNAs that play critical post-transcriptional regulatory roles in skeletal muscle development. We previously found miR-9-5p is abundantly expressed chicken muscle. Here, we demonstrate a new role for as myogenic microRNA regulates The overexpression of significantly inhibited the proliferation and differentiation satellite cells (SMSCs), whereas inhibition had opposite effect. show insulin-like growth factor 2 mRNA-binding protein 3...
Several reproductive hormones were reported to be involved in regulating egg yolk precursor synthesis chickens; however, the mechanism that shows how liver-blood-ovary signal axis works relation age changes has not been yet. Therefore, this study, we observe morphology and histology of liver ovary determine serum biochemical parameters expression abundance critical genes from d90 153. Results show body weight significantly increased d132, while d139. Aside increase weight, other distinct...
The proliferation and differentiation of skeletal muscle satellite cells (SMSCs) play an important role in the development muscle. Our previous sequencing data showed that miR-21-5p is one most abundant miRNAs chicken Therefore, this study, spatiotemporal expression its effects on chickens were explored using vitro cultured SMSCs as a model. results study was highly expressed chickens. overexpression promoted evidenced by increased cell viability, number proliferative phase, mRNA protein...
The fertility of female animals is negatively correlated with increasing chronological age. In aging broiler breeder hens, there a decline in the functionality ovary and liver accompanied by hormonal or endocrine changes, reduction antioxidant capacity, decrease folliculogenesis. Therefore, improving reproductive function hens using dietary strategies great concern to poultry breeder. This study evaluated capacity quercetin (Q), vitamin E (VE), their combination (Q + VE) promote follicle...
Follistatin (FST) is a member of the tissue growth factor β family and secreted glycoprotein that antagonizes many members family, including activin A, differentiation 11, myostatin. The objective this study was to explore use an engineered follistatin therapeutic created by fusing FST315 lacking heparin binding activity N terminus murine IgG1 Fc (FST315-ΔHBS-Fc) as systemic agent in models muscle injury. Systemic administration molecule found increase body weight lean mass after weekly...
Mycotoxin contamination in agro-food systems has been a serious concern globally during the last few decades. Mycotoxins are toxic secondary metabolites produced by fungi when they grow products and feedstuff. Several detection techniques have developed recent years to detect mycotoxins food feed effectively. HPLC based very common usage laboratories for testing of mycotoxins. In years, immuno-based assays is widely used reported at large due its sensitivity limited time. Immuno assay-based...
The rice-fish coculture system (RFS) is one of the most important and environmentally friendly agricultural systems in world. With increasing amounts heavy metal contamination soil water, safe production RFS has been greatly threatened. However, there are no reports on uptake by rice fish a RFS. In this study, model cadmium (Cd)-contaminated with addition 0-40.00 mg kg-1Cd was simulated field. accumulation Cd increased as level increased. Regardless contamination, order root > stem ≈ leaf...
Fomitopsis pinicola is a common brown-rot fungal species found in northern hemisphere. It grows on many different gymnosperm and angiosperm trees. Recent studies show that it complex; three from North America one Europe have been recognized this complex. In the current study, six new complex were discovered East Asia, based morphological characters phylogenetic analyses inferred sequence data of internal transcribed spacer (ITS) regions, second subunit RNA polymerase II (RPB2), translation...
Low oxygen levels and extremely cold weather in high-altitude environments requires more energy intake to maintain body temperature animals. However, little is known about the characteristics of cecal ileac microbiota Tibetan chicken how high low altitude affect gut communities chicken. In present study, chickens (Group HA, 3572 m, 578.5 Pa) their introduced flatland counterparts LA, 580 894.6 cecum ileum identify possible bacterial species that are helpful for host environmental adaption....
Colorectal cancer (CRC) is a common malignancy of the digestive tract. Although chemotherapy considered most effective method for treatment CRC, these drugs have significant side effects. The identification antitumour active ingredients with high efficiency and fewer toxic effects from natural products important. polyphenols artificially cultivated Morchella sextelata (MSP) on CRC were analysed at cellular level. antiproliferative proapoptotic MSP HCT 116 HT‐29 cells determined by...
A 2-month experiment was conducted with three groups (control group, Group 1, and 2) to study the effect of gingerol on growth performance, digestive enzyme activities, antioxidation Macrobrachium nipponense. The results indicated that gingerol, when used as an additive at different feeding frequencies, had effects performance M. weight gain rate (WGR) 1 (fed once a week) 57.89 ± 6.53%, significantly higher than both control group 2 twice (P < 0.05). On 60th day experiment, longest...