Yan Wang

ORCID: 0000-0001-7465-5518
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About
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Research Areas
  • Plant-Microbe Interactions and Immunity
  • Genomics and Phylogenetic Studies
  • Plant Pathogenic Bacteria Studies
  • Legume Nitrogen Fixing Symbiosis
  • Plant Pathogens and Resistance
  • Plant Pathogens and Fungal Diseases
  • Plant Disease Resistance and Genetics
  • Plant Parasitism and Resistance
  • Microbial Community Ecology and Physiology
  • Plant Molecular Biology Research
  • Plant pathogens and resistance mechanisms
  • Plant Gene Expression Analysis
  • Plant Stress Responses and Tolerance
  • Plant Virus Research Studies
  • Mycorrhizal Fungi and Plant Interactions
  • Identification and Quantification in Food
  • Plant tissue culture and regeneration
  • Photosynthetic Processes and Mechanisms
  • Genetic diversity and population structure
  • Plant nutrient uptake and metabolism
  • Nematode management and characterization studies
  • Soybean genetics and cultivation
  • Genetic Mapping and Diversity in Plants and Animals
  • Machine Learning in Bioinformatics
  • Aquaculture disease management and microbiota

West Anhui University
2023-2025

Shandong University
2020-2025

Hunan Agricultural University
2022-2025

Xinjiang University
2008-2025

Zhejiang Provincial Institute of Communications Planning,Design & Research
2025

South China Agricultural University
2022-2025

Nanjing Agricultural University
2015-2024

Ministry of Agriculture and Rural Affairs
2021-2024

Xinjiang Academy of Agricultural Sciences
2009-2024

National Institute for Communicable Disease Control and Prevention
2015-2024

The extracellular space (apoplast) of plant tissue represents a critical battleground between plants and attacking microbes. Here we show that pathogen-secreted apoplastic xyloglucan-specific endoglucanase, PsXEG1, is focus this struggle in the Phytophthora sojae-soybean interaction. We soybean produces an glucanase inhibitor protein, GmGIP1, binds to PsXEG1 block its contribution virulence. P. sojae, however, secretes paralogous PsXEG1-like PsXLP1, has lost enzyme activity but GmGIP1 more...

10.1126/science.aai7919 article EN Science 2017-01-13

Activation of innate immunity by membrane-localized receptors is conserved across eukaryotes. Plant genomes contain hundreds such receptor-like genes and those encoding proteins with an extracellular leucine-rich repeat (LRR) domain represent the largest family. Here, we develop a high-throughput approach to study LRR on genome-wide scale. In total, 257 tobacco rattle virus-based constructs are generated target 386 403 identified in Nicotiana benthamiana for silencing. Using this toolkit,...

10.1038/s41467-018-03010-8 article EN cc-by Nature Communications 2018-02-05

Significance This work describes a facile system for incorporating noncanonical amino acids containing long side-chain thiols using an expanded genetic code. These begin to overcome the distance and geometric constraints of cysteine disulfide can pair with cysteines cross-link more remote sites in proteins. To demonstrate this notion, we constructed library random β-lactamase mutants these grew them at nonpermissive temperatures. We identified mutant enzyme that is cross-linked by one such...

10.1073/pnas.1605363113 article EN Proceedings of the National Academy of Sciences 2016-05-09

Lead (Pb), one of the most toxic heavy metals, can be absorbed and accumulated by plant roots then enter food chain resulting in potential health risks for human beings. The radish (Raphanus sativus L.) is an important root vegetable crop with fleshy taproots as edible parts. Little known about mechanism which radishes respond to Pb stress at molecular level. In this study, Next Generation Sequencing (NGS)-based RNA-seq technology was employed characterize de novo transcriptome identify...

10.1371/journal.pone.0066539 article EN cc-by PLoS ONE 2013-06-20

Abstract The radish ( Raphanus sativus L.) is an important root vegetable crop. In this study, the metabolite profiling analysis of roots exposed to lead (Pb) and cadmium (Cd) stresses has been performed using gas chromatography-mass spectrometry (GC-MS). score plots principal component (PCA) partial least squares-discriminate (PLS-DA) showed clear discrimination between control Pb- or Cd-treated samples. metabolic indicated Pb Cd stress could cause large alteration mainly on sugars, amino...

10.1038/srep18296 article EN cc-by Scientific Reports 2015-12-17

Immune response during pathogen infection requires extensive transcription reprogramming. A fundamental mechanism of transcriptional regulation is histone acetylation. However, how pathogens interfere with this process to promote disease remains largely unknown. Here we demonstrate that the cytoplasmic effector PsAvh23 produced by soybean Phytophthora sojae acts as a modulator acetyltransferase (HAT) in plants. binds ADA2 subunit HAT complex SAGA and disrupts its assembly interfering...

10.1016/j.cub.2017.02.044 article EN cc-by-nc-nd Current Biology 2017-03-16

Salt stress is one of the most representative abiotic stresses that severely affect plant growth and development. MicroRNAs (miRNAs) are well known for their significant involvement in responses to stresses. Although miRNAs implicated salt response have been widely reported numerous species, regulatory roles adaptive radish (Raphanus sativus L.), an important root vegetable crop worldwide, remain largely unknown.Solexa sequencing two sRNA libraries from NaCl-free (CK) NaCl-treated (Na200)...

10.1186/s12864-015-1416-5 article EN cc-by BMC Genomics 2015-03-16

Phytophthora pathogens secrete an array of specific effector proteins to manipulate host innate immunity promote pathogen colonization. However, little is known about the targets effectors and mechanisms by which increase susceptibility. Here we report that soybean sojae uses essential PsAvh262 stabilize endoplasmic reticulum (ER)-luminal binding immunoglobulin (BiPs), act as negative regulators plant resistance Phytophthora. By stabilizing BiPs, suppresses ER stress-triggered cell death...

10.1038/ncomms11685 article EN cc-by Nature Communications 2016-06-03

Bacterial pneumonia is a common disease in dairy herds worldwide, which brings great economic losses to farmers. Sodium butyrate (SB), an inhibitor of histone deacetylase, plays important role limiting inflammation. The purpose this study was investigate the protective effects SB on lipopolysaccharide (LPS)-induced acute lung injury (ALI) mice and explore potential mechanism protection. A total 30 ICR were randomly divided into three groups (n = 10): phosphate-buffered saline (PBS)...

10.1021/acs.jafc.8b06359 article EN Journal of Agricultural and Food Chemistry 2019-01-20

Abstract Cultivated strawberry (Fragaria × ananassa), a perennial herb belonging to the family Rosaceae, is complex octoploid with high heterozygosity at most loci. However, there no research on haplotype of genome. Here we aimed obtain high-quality genome cultivated cultivar, “Yanli”, using single molecule real-time sequencing and high-throughput chromosome conformation capture technology. The “Yanli” was 823 Mb in size, long terminal repeat assembly index 14.99. phased into two haplotypes,...

10.1093/hr/uhad002 article EN cc-by Horticulture Research 2023-01-01

Summary High‐quality radish ( Raphanus sativus ) genome represents a valuable resource for agronomical trait improvements and understanding evolution among Brassicaceae species. However, existing assembly remains fragmentary, which greatly hampered functional genomics research genome‐assisted breeding. Here, using NAU‐LB inbred line, we generated reference of 476.32 Mb with scaffold N50 56.88 by incorporating Illumina, PacBio BioNano optical mapping techniques. Utilizing Hi‐C data, 448.12...

10.1111/pbi.14011 article EN cc-by-nc-nd Plant Biotechnology Journal 2023-01-17

Abstract The soil microbiota is critical to plant performance. Improving the ability of plant-associated probiotics thus essential for establishing dependable and sustainable crop yields. Although fertilizer applications may provide an effective way steering microbes, it still unknown how positive effects soil-borne can be maximized their are mediated. This work aims seek ecological mechanisms involved in cabbage growth using bio-organic fertilizers. We conducted a long-term field experiment...

10.1038/s41522-023-00416-1 article EN cc-by npj Biofilms and Microbiomes 2023-07-05
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