A5072771340- Luminescence and Fluorescent Materials
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Nanoplatforms for cancer theranostics
- Molecular Sensors and Ion Detection
- Advanced biosensing and bioanalysis techniques
- Perovskite Materials and Applications
- Organic Light-Emitting Diodes Research
- Photodynamic Therapy Research Studies
- Organic Electronics and Photovoltaics
- Porphyrin and Phthalocyanine Chemistry
- Photochromic and Fluorescence Chemistry
- Advanced Photocatalysis Techniques
- Sulfur Compounds in Biology
- HER2/EGFR in Cancer Research
- Conducting polymers and applications
- Crystallography and molecular interactions
- Lung Cancer Treatments and Mutations
- Advanced Breast Cancer Therapies
- Electrochemical Analysis and Applications
- Polydiacetylene-based materials and applications
- Genetic and phenotypic traits in livestock
- Radical Photochemical Reactions
- Machine Learning in Materials Science
- Blood Coagulation and Thrombosis Mechanisms
Institute of Applied Physics and Computational Mathematics
2013-2025
Zhejiang University of Technology
2016-2025
Renmin Hospital of Wuhan University
2022-2025
Xiangyang Central Hospital
2020-2025
Hunan University
2025
Inner Mongolia University
2007-2024
National University of Mongolia
2024
Baotou Medical College
2023-2024
Zhejiang University
2008-2023
Shandong Provincial Hospital
2023
Research on materials with pure organic room temperature phosphorescence (RTP) and their application as single-molecule white light emitters is a hot area relies the design of highly efficient RTP luminogens. Herein, facile strategy heavy-atom-participated anion-π+ interactions proposed to construct RTP-active salt compounds (1,2,3,4-tetraphenyloxazoliums different counterions). Those heavy-atom counterions (bromide iodide ions) exhibit outstanding due external heavy atom effect via...
Recent years have witnessed the significant role of anion-π+ interactions in many areas, which potentially brings opportunity for development aggregation-induced emission (AIE) systems. Here, a new strategy that utilized to block detrimental π-π stacking was first proposed develop inherent-charged AIE Two AIE-active luminogens, namely, 1,2,3,4-tetraphenyloxazolium (TPO-P) and 2,3,5-triphenyloxazolium (TriPO-PN), were successfully synthesized. Comprehensive techniques such as single-crystal...
Tumor hypoxia seriously impairs the therapeutic outcomes of type II photodynamic therapy (PDT), which is highly dependent upon tissue oxygen concentration. Herein, a facile strategy acceptor planarization and donor rotation proposed to design I photosensitizers (PSs) photothermal reagents. Acceptor can not only enforce intramolecular charge transfer redshift NIR absorption but also PSs from photochemical pathways. Donor optimizes conversion efficiency (PCE). Accordingly, three...
Fluorescent nanoparticles (NPs) based on luminogens with aggregation-induced emission characteristic (AIEgens), namely AIE dots, have received wide attention because of their antiquenching attitude in and reactive oxygen species (ROS) generation when aggregated. However, few reports are available how to control optimize fluorescence ROS ability. Herein, it is reported that enhancing the intraparticle confined microenvironment an effective approach advanced permitting boosted cancer...
Abstract Pathogen infections and cancer are two major human health problems. Herein, we report the synthesis of an organic salt photosensitizer (PS), called 4TPA‐BQ, by a one‐step reaction. 4TPA‐BQ presents aggregation‐induced emission features. Owing to reactive oxygen species generated sufficiently small Δ E ST , shows satisfactorily high 1 O 2 generation efficiency 97.8 %. In vitro in vivo experiments confirmed that exhibited potent photodynamic antibacterial performance against...
Acrylonitriles with aggregation-induced emission (AIE) characteristics have been found to show promising applications in two-photon biomedical imaging. Generally, elaborate synthetic efforts are required achieve different acrylonitriles distinct functionalities. In this work, we first reported the synthesis of two group-functionalized AIE-active (TPAT-AN-XF and 2TPAT-AN) obtained simply by mixing same reactants at temperatures using a facile transition metal-free method. These AIE luminogens...
Lipid droplets are highly associated with obesity, diabetes, inflammatory disorders, and cancer. A reliable two-photon dye for specific lipid imaging in live cells tissues at ultralow concentration has rarely been reported. In this work, four new aggregation-induced emission luminogens (AIEgens) based on the naphthalene core were designed synthesized droplet staining. The molecules, namely, NAP AIEgens, exhibit large Stokes shift (>110 nm), high solid-state fluorescence quantum yield (up to...
Phototheranostics with second near-infrared (NIR-II) imaging and photothermal effect have become a burgeoning biotechnology for tumor diagnosis precise treatment. As important parameters of phototheranostic agents (PTAs), fluorescence quantum yield (QY) conversion efficiency (PCE) are usually considered as pair contradictions that is difficult to be simultaneously enhanced. Herein, fluorination strategy designing A-D-A type PTAs synchronously improved QY PCE proposed. Experimental results...
Polycyclic aromatic hydrocarbons (PAHs) with boron-nitrogen (BN) moieties have attracted tremendous interest due to their intriguing electronic and optoelectronic properties. However, most of the BN-fused π-systems reported date are difficult modify exhibit traditional aggregation-caused quenching (ACQ) characteristics. This phenomenon greatly limits scope application. Thus, continuing efforts seek novel, structurally distinct functionally diverse structures highly desirable. Herein, we...
Stimulated emission depletion (STED) nanoscopy has broadened our horizons to unravel mysterious functions of cellular structures on an unparalleled nanometer scale. Nevertheless, intense laser power is a general prerequisite for STED super-resolution imaging with satisfactory resolution, inevitably leading severe photobleaching fluorophores, irreparable photodamage biosamples, and impaired quality. Herein, by modulating distinct acceptor units, series donor–acceptor–acceptor structured...
Abstract 2D materials, especially superlattices with tailored geometries, represent an emerging class of promising electrocatalysts for sustainable energy conversion. However, the development has been largely confined to self‐assembled layered structures, and it remains a great challenge rationally design distances between neighboring metal sites at atomic level match adsorption configurations key species in target reaction pathways. In this work, general strategy is reported synthesizing Ru...
Abstract Development of new aggregation‐induced emission (AIE) luminogens has been a hot research topic because they thoroughly solve the notorious aggregation‐caused quenching effect confronted in conventional fluorogens and their promising applications in, for example, organic light‐emitting diodes, chemo‐ biosensors bioimaging. Many AIE (AIEgens) have prepared but most them are silole, tetraphenylethene, distyrylanthracene, derivatives. In this work, based on skeleton tetraphenylpyrazine...
An aggregation induced emission (AIE) based bioimaging probe, TPE-Gal, was designed for light-up imaging of β-galactosidase in living cells. The applicability TPE-Gal endogenous activity confirmed OVCAR-3
Carbon monoxide (CO) is a significant gasotransmitter that naturally modulates inflammatory responses. Visualization of CO in situ would help to reveal its physiological/pathological functions. Unfortunately, most existing fluorescent probes show aggregation-caused quenching (ACQ) properties. Herein, we report the reaction-based probe (BTCV-CO) with aggregation-induced emission (AIE) characteristics for detection and imaging. This ratiometric AIE showed excellent stability, high sensitivity...
Many aggregation-induced emission (AIE) materials are featured by the diphenylethene (DPE) moiety which exhibits rich photophysical and photochemical activities. The understanding of these activities behind AIE is essential to guide design fluorescent with improved performance. Herein fusing a flexible DPE rigid spiro scaffold, we report class novel deep-blue material solid-state quantum yield (ΦF) up 99.8%. Along phenomenon, identified reversible photocyclization (PC) on visible chromism,...
Abstract Organic luminescent materials are one of the research hotspots worldwide. The efficiency these can be tuned by introducing noncovalent interactions. Ion−π interactions, mainly including anion−π interactions and cation−π relatively new but powerful with extensive applications in supramolecular chemistry. use ion−π to fabricate highly is initiated since they were introduced develop aggregation‐induced emission luminogens 2017. Then, this field undergoing through challenging very...
The performances of second near-infrared (NIR-II) organic phototheranostic agents (OPTAs) depend on both molecular structure and packing when used as nanoparticles (NPs). Herein, we proposed a facile structural isomerization-induced 3D spatial donor (D)-acceptor (A) interlocked network for achieving NIR-II OPTAs. Two isomers, 4MNVDPP 6MNVDPP were synthesized formulated into NPs. 6MNVDPP, which has larger electrostatic potential difference, exhibits compact D-A in the crystal form, while...
Lipid droplets (LDs) containing cytosolic and nuclear LDs have recently received increasing attention because of their diverse biological roles in living systems. However, developing fluorescent probes for super-resolution visualization these subcellular still remains challenging due to insufficient fluorescence brightness poor membrane permeability. Herein, we rationally synthesized a series ultrabright solvatochromic based on benzoboranils (BBAs) LD-specific imaging using structured...
The low oxygen dependence of type I photosensitizers (PSs) has made them a popular choice for treating solid tumors. However, the drawbacks poor water solubility, short emission wavelength, stability, and inability to distinguish cancer cells from normal limit application most PSs in clinical therapy. Thereby, developing novel overcoming these problems is an urgent but challenging task. Herein, by utilizing distinctive structural characteristics anion-π+ interactions, highly water-soluble PS...
Type I photosensitizers (PSs) with an aggregation-induced emission (AIE) feature have received sustained attention for their excellent theranostic performance in the treatment of clinical diseases. However, development AIE-active type PSs strong reactive oxygen species (ROS) production capacity remains a challenge due to lack in-depth theoretical studies on aggregate behavior and rational design strategies. Herein, we proposed facile oxidization strategy enhance ROS generation efficiency...
Abstract While second near-infrared (NIR-II) fluorescence imaging is a promising tool for real-time surveillance of surgical operations, the previously reported organic NIR-II luminescent materials in vivo are predominantly activated by expensive lasers or X-ray with high power and poor illumination homogeneity, which significantly limits their clinical applications. Here we report white-light activatable agent taking advantages strong intramolecular/intermolecular D-A interactions...
ADVERTISEMENT RETURN TO ISSUEPREVLetterNEXTFree-Radical-Initiated Coupling Reaction of Alcohols and Alkynes: Not C−O but C−C Bond FormationZhong-Quan Liu*†, Liang Sun‡, Jian-Guo Wang‡, Jie Han‡, Yan-Kai Zhao†, Bo Zhou†View Author Information Institute Organic Chemistry, Gannan Normal University, Ganzhou, Jiangxi 341000, P. R. China, State Key Laboratory Applied Chemistry Department Lanzhou 730000, China[email protected]†Lanzhou University.‡Gannan University.Cite this: Org. Lett. 2009, 11, 6,...