A5066944598- Bone fractures and treatments
- Hip and Femur Fractures
- Orthopaedic implants and arthroplasty
- Pelvic and Acetabular Injuries
- Emergency and Acute Care Studies
- Orthopedic Surgery and Rehabilitation
- Elbow and Forearm Trauma Treatment
- Hip disorders and treatments
- Orthopedic Infections and Treatments
- Radioactivity and Radon Measurements
- Sports injuries and prevention
- RNA Interference and Gene Delivery
- Systemic Sclerosis and Related Diseases
- Axon Guidance and Neuronal Signaling
- Bone and Joint Diseases
- Healthcare and Environmental Waste Management
- Sympathectomy and Hyperhidrosis Treatments
- Healthcare cost, quality, practices
- Hippo pathway signaling and YAP/TAZ
- Musculoskeletal synovial abnormalities and treatments
- Wnt/β-catenin signaling in development and cancer
- Trauma and Emergency Care Studies
- Total Knee Arthroplasty Outcomes
- Climate Change and Health Impacts
- Sarcoma Diagnosis and Treatment
Elisabeth-TweeSteden Ziekenhuis
2018-2023
Noordwest Ziekenhuisgroep
2020
Clinical Orthopaedics and Related Research
2020
Amsterdam UMC Location Vrije Universiteit Amsterdam
2013-2016
Groene Hart Ziekenhuis
2013
Leiden University
2013
Leiden University Medical Center
2011-2012
Medisch Centrum Alkmaar
2012
Osteosarcoma (OS) is the most common bone tumour in children and adolescents. Despite aggressive therapy regimens, treatment outcomes are unsatisfactory. Targeted delivery of drugs can provide higher effective doses at site tumour, ultimately improving efficacy existing therapy. Identification suitable receptors for drug targeting an essential step design targeted OS. We conducted a comparative analysis surface proteome human OS cells osteoblasts using cell biotinylation combined with...
Sixty-two centres in 16 countries contributed with 2,694 open fractures cases to an international, multi-centric, retrospective cohort study involving different healthcare settings. The INTELLECT results show that there are significant disparities on the management of lower limb internationally. A timely, multidisciplinary, guideline-directed care is a protective factor for developing infective complications, non-union and requiring amputation.
// Jantine Posthuma De Boer 1 , Pim W. van Egmond 2 Marco N. Helder 1,3 Renée X. de Menezes 4 Anne-Marie Cleton-Jansen 5 Jeroen A.M. Beliën 6 Henk M. Verheul 7 Barend J. Royen Gert-Jan J.L. Kaspers 8 Victor Beusechem Department of Orthopaedic Surgery, VU University Medical Center, Amsterdam, the Netherlands Medisch Centrum Alkmaar (MCA), 3 Research Institute MOVE/Skeletal Tissue Engineering Group Amsterdam (STEGA), Epidemiology and Biostatistics, Pathology, Leiden Center (LUMC), RNA...
Abstract Purpose Evidence for a hospital volume–outcome relationship in hip fracture surgery is inconclusive. This study aimed to analyze the association between volume as continuous parameter and several processes outcomes of care. Methods Adult patients registered nationwide Dutch Hip Fracture Audit (DHFA) 2018 2020 were included. The annual turnaround times (time on emergency ward, < 48 h length stay), orthogeriatric co-treatment case-mix adjusted in-hospital 30 days mortality was...
PURPOSE: Worldwide, many displaced distal forearm fractures in children are treated by closed reduction under local anesthesia and cast immobilization. If mal-alignment of the fracture persists after initial attempt, final will be performed general anesthesia, followed The purpose this study was to analyze results minimally invasive fixation with K-Wire or ESIN compared plaster We hypothesize that primary percutaneous prevents secondary redisplacement reduces number interventions. METHODS:...
The failure scenario in total hip arthroplasty (THA), younger patients, is dependent on the fixation and wear of acetabular component. In selected cases, where endoprosthetic replacement femoral head unavoidable for limb salvage or functional recovery, hemiarthroplasty can be chosen as an alternative. purpose this study to evaluate treatment strategy young patients with osteonecrosis a tumour proximal femur.Between 1985 2008, 42 hemiarthroplasties (unipolar bipolar) were performed than 65...
Forearm fractures in children are common. When conservative treatment fails, internal fixation with Elastic Stable Intramedullary Nailing (ESIN) become the first choice operative of diaphyseal forearm shaft fractures. Refractures intramedullary nail situ known to occur but formal guidelines guide management such lacking. We present a well-documented case radius midshaft refracture 12-year-old boy situ, managed by closed reduction. Literature is reviewed for this type complication, 30 similar...
The Dutch Hip Fracture Audit (DHFA), a nationwide hip fracture registry in the Netherlands, registers patients and aims to improve quality of care since 2016. This study shows trends data during first 5 years acquisition within DHFA, as well over time for designated indicators (QI).All registered DHFA between 1-1-2016 31-12-2020 were included. Data quality-registry case coverage completeness-and baseline characteristics are reported. Five QI analysed: Time surgery < 48 h, assessment...
The most recent diagnostic criteria for periprosthetic joint infection (PJI) include the use of alpha-defensin (AD) lateral-flow (LF) test, but hip and knee arthroplasties were usually combined in previous studies. This prospective study was designed to examine accuracy AD-LF test diagnosis PJI chronic painful total (THA).Patients with prospectively enrolled between March 2018 May 2020. Exclusion included acute or an insufficient amount synovial fluid. modified Musculoskeletal Infection...
Endovascular intervention is not previously described in patients with exacerbated Raynaud ’ s phenomenon (RP). A 45-year-old male secondary RP and CREST (Calcinosis cutis, Raynaud’s phenomenon, Esophageal dysmotility, Sclerodactyly Telangiectasia) a smoking history, who was noncompliant the non-interventional treatment, presented necrosis of right hand RP. An intra-arterial digital subtraction angiography (DSA) showed occlusion distal ulnar radial arteries. Initial pharmacological therapy...